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La esquistosomiasis como factor de riesgo del cáncer de vejiga. Hospital Central de Nampula, Mozambique


 
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Revista Médica Electrónica

 ISSN 1684-1824

LEON-RAMOS, Osmany Lázaro et al. Schistosomiasis as a risk factor for bladder cáncer. Central Hospital of Nampula, Mozambique. []. , 45, 1, pp. 70-82.   28--2023. ISSN 1684-1824.

Introduction:

schistosomiasis is the most important trematode infection globally. Squamous cell carcinoma constitutes 2% of all the histological types of bladder cancer; however, the incidence of this variety of cancer in squistosomiasis-endemic countries is higher.

Objective:

to evaluate the relationship between squistosomiasis and bladder cancer in patients from the Central Hospital of Nampula.

Materials and methods:

a cross-sectional descriptive observational study was carried in the period between January 2014 and December 2020. Patients were divided into age-groups, by 10-year intervals. Biopsy samples of bladder tumors were taken, classified by histological type, in addition to findings related to squistosomiasis infestations and bladder cancer presentation forms. The universe consisted of 184 patients and the sample of 135 cases.

Results:

it was found that the largest number of patients with bladder cancer is male; squamous cell carcinoma is the most frequent histological type, representing 84.3% of the total. Cystitis, schistosome and their eggs were present in almost all the biopsies performed. Its most frequent presentation forms were hematuric and painful cystitis.

Conclusions:

bladder cancer showed higher incidence at the ages between 30 and 69 years. The squamous cell carcinoma was the most frequent, and its relationship with cystitis and schistosome infection was present in more than 90% of biopsies.

: bladder cancer; schistosomiasis; cystitis; hematuria.

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