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Revista Cubana de Anestesiología y Reanimación
versión On-line ISSN 1726-6718
Resumen
HERNANDEZ ORTEGA, Rudy et al. Economic impact of remote ischemic preconditioning on myocardial revascularization. Rev cuba anestesiol reanim [online]. 2013, vol.12, n.2, pp.108-115. ISSN 1726-6718.
Background: to condition the heart to improve its endogenous cardioprotective capacity using brief remote ischemia provides a novel potential approach to myocardial protection during cardiac surgery. Objective: to identify the economic impact of remote ischemic preconditioning in surgically revascularized patients. Methods: an experimental prospective longitudinal study was conducted in two groups of 100 people who underwent revascularization by coronary artery graft. A tourniquet was placed on the non-dominant arm in those who were included in the test study group, alternating three insufflations with three desinsufflations with a pressure of 200 mmHg, each one being maintained for five minutes. This procedure was performed prior to, during and after the greater ischemic event that corresponds to the pinching of the coronary artery. Results: an important decrease of the consumption of inotropic, vasoactive and other drugs was achieved, saving an important sum, decreasing hospital costs, and also proving a reduction in the incidence of lethal ventricular arrhythmias, low cardiac output and postoperative death which were, in all cases, below the prediction previously made for these complications. Conclusions: remote ischemic preconditioning can be an important tool to be considered in the antischemic protection of myocardial revascularization that can diminish morbimortality and hospital costs.
Palabras clave : remote ischemic preconditioning; post-reperfusion injury; CABG; coronary artery; CK-MB; morbimortality; hospital costs.