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Revista Cubana de Anestesiología y Reanimación
versão On-line ISSN 1726-6718
Resumo
GONZALEZ LOPEZ, Armando et al. Usefulness of ondansetron versus dexamethasone as postoperative antiemetic prophylaxis during major gynecologic surgery. Rev cuba anestesiol reanim [online]. 2020, vol.19, n.3, e629. Epub 01-Out-2020. ISSN 1726-6718.
Introduction:
Postoperative nausea and vomiting are an unwanted sequel during the anesthetic recovery stage.
Objective:
To evaluate the usefulness of dexamethasone compared with ondansetron for the prevention of postoperative nausea and vomiting after major gynecological surgical procedures, under general orotracheal anesthesia.
Method:
A prospective, analytical and observational study was carried out with 84 patients older than 19 years of age, at Miguel Enríquez Hospital Clinical-Surgical Hospital, from October 2018 to September 2019, divided sequentially, in order of arrival at the surgical unit, into two groups. The group 1 was administered dexamethasone (4 mg intravenously), and the group 2 was administered ondansetron (4 mg), 30 min before the end of the surgery.
Results:
The average risk of postoperative nausea and vomiting prevailed significantly among patients aged 41-50 years. Excellent and good conditions predominated (p>0.05) in terms of effectiveness of prophylactic treatment. Headache prevailed significantly in the group 2. Most of the patients did not present adverse events.
Conclusions:
Ondansetron and dexamethasone are useful for postoperative nausea and vomiting prophylaxis among patients who received major gynecological surgery, under general orotracheal anesthesia, a reason why it is considered a safe treatment, with mild adverse events and easy control.
Palavras-chave : postoperative nausea and vomiting; dexamethasone; ondansetron.