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Revista Habanera de Ciencias Médicas

On-line version ISSN 1729-519X

Abstract

MORALES LEON, José Angel et al. Quality control of pharmaceutical formulations obtained from cassia uniflora mill. Rev haban cienc méd [online]. 2011, vol.10, n.4, pp.532-539. ISSN 1729-519X.

Introduction: Cassia uniflora Mill has a high biological availability; It is used in treatments for spasmodic pains, cutaneous eruptions and some infections of bacteriological origin. The most useful parts are its leaves and seeds. Objectives: To determine the specifications of quality control for tinctures made up from leaves and seeds of Cassia uniflora Mill at 20%. Material and methods: Tincture at 20% was made up of the powders of leaves and seeds, using as menses a hydroethanolic solution. Determination of quality control specifications of the tinctures were made taking into account four parameters: pH, refraction index, total solids and relative density. Results: Data obtained in the quality control of the tinctures at 20% are among the ranks of quality established by the standards. Discussion: Quality parameters show that tinctures at 20% from leaves and seeds of Cassia uniflora Mill had no relevant changes that could affect its pharmacological quality, therefore they have a certain degree of stability. Conclusions: The specifications of the quality control made to the tinctures indicate that under the conditions applied the elaborated products are innocuous, so they are totally guaranteed for therapeutically use.

Keywords : Cassia uniflora Mill; quality control; pH; relative density; pharmaceutical formulations; tincture; innocuousness.

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