SciELO - Scientific Electronic Library Online

 
vol.17 número5Siria Pérez Fabas: notoria jefa de enfermeríaConsumo de antihipertensivos en el Hospital “Manuel Fajardo”. 2013-2017 índice de autoresíndice de materiabúsqueda de artículos
Home Pagelista alfabética de revistas  

Servicios Personalizados

Revista

Articulo

Indicadores

  • No hay articulos citadosCitado por SciELO

Links relacionados

  • No hay articulos similaresSimilares en SciELO

Compartir


Revista Habanera de Ciencias Médicas

versión On-line ISSN 1729-519X

Resumen

LA ROSA HERNANDEZ, Deyanira et al. Serologic markers of viral and autoimmune liver diseases in celiac patients treated at the Institute of Gastroenterology. Rev haban cienc méd [online]. 2018, vol.17, n.5, pp.669-680. ISSN 1729-519X.

Introduction:

The spectrum of hepatic involvement in celiac disease is very broad and includes viral and autoimmune hepatopathies.

Objective:

To characterize the behavior of serologic markers of viral and autoimmune hepatopathies in adult celiac patients treated at the Institute of Gastroenterology.

Materials and Methods:

A cross-sectional observational study was conducted in 43 adult celiac patients treated at the Institute of Gastroenterology of Havana from March 2016 to March 2017. Prior informed consent, biochemical and serologic studies were carried out in all cases, in order to identify hepatitis B and C virus infections and humoral immune response to liver and systemic autoantibodies. Frequency distributions were used for statistical analysis, and Fisher's exact test was used for the comparison between groups.

Results:

58.1% of the patients presented hypophosphatasemia and hypertransaminasemia in 14%, with no coincidence between the cases recorded. The 100% of the celiac patients were negative for hepatitis C virus. The positivity of liver autoantibodies was recorded between 2,3% and 14% of the patients evaluated. There was a significant association between hypertransaminasemia and the presence of serum antibodies against tissue transglutaminase.

Conclusions:

The expression markers of liver autoimmunity in celiac patients was frequent, but not the presence of markers of viral hepatopathy.

Palabras clave : celiac disease; hypertransaminasemia; viral hepatitis; autoimmune liver disease.

        · resumen en Español     · texto en Español     · Español ( pdf )