SciELO - Scientific Electronic Library Online

 
vol.19 issue2Gender differences in the clinical and angiographic presentation of Acute Coronary SyndromeClinical-epidemiological characteristics of COVID-19 author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Services on Demand

Journal

Article

Indicators

  • Have no cited articlesCited by SciELO

Related links

  • Have no similar articlesSimilars in SciELO

Share


Revista Habanera de Ciencias Médicas

On-line version ISSN 1729-519X

Abstract

GIRALT-HERRERA, Alejandro; ROJAS-VELAZQUEZ, Jesús Miguel  and  LEIVA-ENRIQUEZ, Jessica. Relationship between COVID-19 and Hypertension. Rev haban cienc méd [online]. 2020, vol.19, n.2, e3246.  Epub Apr 22, 2020. ISSN 1729-519X.

Introduction:

The first three months of 2020 have been influenced by the spreading of a pandemic caused by the SARS-coronavirus 2, which causes COVID-19 infection that in some cases is associated with acute respiratory distress syndrome.

Objective:

To identify the relationship between COVID-19 and hypertension.

Material and Methods:

A bibliographic review was carried out using database search engines. In addition, reference literature in Cardiology was used as well as information from official government websites such as WHO/PAHO and other scientific societies.

Development:

Coronaviruses enter into target cells through a spike S protein, whose S1 surface unit is coupled to the angiotensin-converting enzyme 2 as a receptor. In the different revised series, the clear relationship between the history of arterial hypertension and the unfavorable evolution is observed in patients with COVID-19. In an extensive literature search, there is no scientific evidence for discontinuation of angiotensin-converting enzyme inhibitors or angiotensin receptor blockers in hypertensive patients with COVID-19.

Conclusions:

The angiotensin-converting enzyme acts as a SARS-CoV2 receptor. Hypertensive individuals have a less favorable evolution course of the condition caused by this virus. Discontinuation of treatment with angiotensin-converting enzyme inhibitors or angiotensin receptor blockers is not advisable in hypertensive patients with COVID-19.

Keywords : COVID-19; SARS-CoV 2; 2019-Ncov; SARS; coronavirus; hypertension.

        · abstract in Spanish     · text in Spanish     · Spanish ( pdf )