Introduction:

Coronaviruses are a large family of viruses that can cause diseases in both animals and humans. The SARS-CoV-2 is a new virus that belongs to the Orthocoronavirinae subfamily. The infection can be mild, moderate or severe regarding the form of presentation and the accompanying symptoms. When there are no complications, the viral infection of the upper respiratory tract is accompanied by nonspecific symptoms like fever, cough, sore throat, nasal congestion, general malaise, headaches and muscle pain.

Objective:

To describe the extra-pulmonary manifestations of the novel coronavirus infection SARS-CoV-2.

Material and Methods:

A bibliographic review from a total of 56 references was made; articles and information in Spanish and English languages available from databases such as PubMed/MedLine, SciELO, Scopus and other open access journals were used.

Development:

Different authors have reported extra-pulmonary manifestations in patients with COVID-19. Nausea, vomiting, diarrhea and hepatic lesions among others have been reported in the digestive system; arterial hypotension, arrhythmias and myocarditis have been found in the cardiovascular system; acute kidney injury has been observed in the renal system; hyponatremia was reported in a case in the endocrine-metabolic system; epilepsy, anosmia, cerebrovascular disease and others have been observed in the neurological system; additionally, cutaneous manifestations have been observed as exanthematic lesions.

Conclusions:

Besides the lung manifestations typical of pneumonia that the novel coronavirus infection SARS-CoV-2 causes, extra-pulmonary manifestations can be present in other systems such as: the digestive, cardiovascular, endocrine-metabolic, neurological, and renal ones. Skin lesions can also occur.

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