Introduction:

The identification of the main epidemiological clinical factors that determine the causes of mortality in hospitalized patients is a pressing need, mainly when the efforts made at present do not allow us to take actions based on the identification of the causes of the aforementioned event.

Objective:

To identify the prognostic factors for mortality caused by infectious agents in a high complexity hospital in the city of Cartagena, Colombia.

Material and Methods:

A retrospective case-control study was conducted in 86 cases and 258 control samples that met the eligibility criteria, at the 1: 3 ratio. Bivariate analyses and a subsequent multivariate analysis that included binary logistic regression methods were also performed.

Results:

In the multivariate analysis, the risk of mortality is determined by variables such as male sex (ORa 1,695 95 % CI: 1.005-2.856); cancer (ORa 2,389 95 % CI 1,230-4,642); immunosuppression (ORa 3.211 95 % CI 1.004-10.26); mechanical ventilation (ORa 2.541 95 % CI 1.128-5.722); stay in the ICU (ORa 2,331 95 % CI 1,227-4,425) and infection caused by carbapenemase-producing bacteria (ORa 4,778 95 % CI 1,313-17.38).

Conclusions:

Male patients with cancer or any other form of immunosuppression who require the use of a mechanical ventilator or admission to the intensive care unit who also develop infections caused by carbapenemase-producing bacteria, are at greater risk of death from an infectious agent.

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