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Revista Habanera de Ciencias Médicas

versión On-line ISSN 1729-519X


LORDUY GOMEZ, Jaime et al. Prognostic factors for mortality caused by an infectious agent in a high complexity hospital in Cartagena-Colombia. Rev haban cienc méd [online]. 2021, vol.20, n.3, e3647.  Epub 16-Jun-2021. ISSN 1729-519X.


The identification of the main epidemiological clinical factors that determine the causes of mortality in hospitalized patients is a pressing need, mainly when the efforts made at present do not allow us to take actions based on the identification of the causes of the aforementioned event.


To identify the prognostic factors for mortality caused by infectious agents in a high complexity hospital in the city of Cartagena, Colombia.

Material and Methods:

A retrospective case-control study was conducted in 86 cases and 258 control samples that met the eligibility criteria, at the 1: 3 ratio. Bivariate analyses and a subsequent multivariate analysis that included binary logistic regression methods were also performed.


In the multivariate analysis, the risk of mortality is determined by variables such as male sex (ORa 1,695 95 % CI: 1.005-2.856); cancer (ORa 2,389 95 % CI 1,230-4,642); immunosuppression (ORa 3.211 95 % CI 1.004-10.26); mechanical ventilation (ORa 2.541 95 % CI 1.128-5.722); stay in the ICU (ORa 2,331 95 % CI 1,227-4,425) and infection caused by carbapenemase-producing bacteria (ORa 4,778 95 % CI 1,313-17.38).


Male patients with cancer or any other form of immunosuppression who require the use of a mechanical ventilator or admission to the intensive care unit who also develop infections caused by carbapenemase-producing bacteria, are at greater risk of death from an infectious agent.

Palabras clave : Drug resistance; bacterial; cross-infection; gram-negative bacterial infections; gram-positive bacteria infections; mortality.

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