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Revista Cubana de Reumatología

versión On-line ISSN 1817-5996


REYES LLERENA, Gil Alberto et al. Rheumatic Diseases and Metabolic Complications in HIV/AIDS Patients with Highly Efficient Antiretroviral Treatment. Rev Cuba Reumatol [online]. 2018, vol.20, n.3, e650. ISSN 1817-5996.


HIV/AIDS infection is one of the main health problems worldwide, with high morbidity and mortality. Different epidemiological studies have confirmed that 36.3 million people worldwide were living with HIV until 2015. So far, 78 million have been infected since 1981, the year in which the epidemic began, and 25% of patients do not know they are infected, which spreads infection.


To carry out a literature review about HIV/AIDS infection, its complications in rheumatic metabolic manifestations, and its response to highly efficient antiretroviral treatment.


A literature search was carried out in the databases PudMed/MEDLINE, Cumed and Lilac, as well as in the regional information sources SciELO and ScienceDirect, using the key phrases manifestaciones reumáticas y VIH-SIDA [rheumatic manifestations and HIV-AIDS], complicaciones metabólicas y VIH-SIDA [metabolic complications and HIV-AIDS], tratamiento antirretroviral de alta eficiencia y VIH-SIDA [high-efficiency antiretroviral treatment and HIV-AIDS], in order to recover the articles about HIV-AIDS and rheumatic and metabolic complications and their response to highly efficient antiretroviral treatment.


78 articles and nine texts dealing about the aforementioned topics were recovered; of them, 55 documents that are part of our bibliographical references were useful for our purposes, which were grouped according to the different topics proposed for this study. We reached useful conclusions for our scientific community.


Rheumatic and autoimmune diseases have been diagnosed very frequently in patients infected with HIV/AIDS in Cuba and worldwide during the era prior to highly efficient antiretroviral treatment. Its incorporation into the therapeutic approach has increased the survival expectations of these patients, in addition to the substantial decrease in the appearance of clinical symptoms and conditions, especially the inflammatory arthritic conditions, seronegative spondyloarthropathies, psoriasis and opportunistic infections.

Palabras clave : rheumatic diseases; metabolic complications; HIV/AIDS; highly efficient antiretroviral treatment.

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