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Revista Cubana de Reumatología

versión On-line ISSN 1817-5996


BERMUDEZ MARRERO, Witjal Manuel et al. Systemic Lupus Erythematosus, Ten years of follow up. Rev Cuba Reumatol [online]. 2019, vol.21, n.2, e87.  Epub 01-Ago-2019. ISSN 1817-5996.


Systemic Lupus Erythematosus is a relatively frequent disease of universal distribution. Its incidence varies according to the characteristics of the studied population such as age, gender and ethno. It is a chronic and autoimmune disease, which cause is not clear at all.


to characterize clinically and epidemiologically the patients with systemic lupus erythematosus.


A descriptive investigation of 112 patients with diagnosis of systemic lupus erythematosus assisted at Arnaldo Milián Castro University Hospital was carried out from January 2008 to December 2017.


patients between 30 and 39 years of age were the most representative with a higher incidence in the female sex. High blood pressure prevailed as previous history and coffee as toxic habit. There was a higher affection of the osteomyoarticular system followed by skin and mucosa. The combination of Prednisone and Azathioprine was the most used treatment. Infections were the main cause of death.


systemic Lupus Erythematosus is present with major frequency in female young patients, with a high risk of systemic affection as well as presenting a life-threatening evolution secondary to infections.

Palabras clave : systemic lupus erythematosus; autoimmune; autoantibodies; aoutoantigens.

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