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Revista Cubana de Reumatología

versión On-line ISSN 1817-5996


REMEDIOS BATISTA, Susel Elisabet; PROENZA CLARO, Mayelin  y  RODRIGUEZ RAMIREZ, Lourdes Gladis. Systemic Sclerosis and neoplastic purpose of a study at Holguin province. Rev Cuba Reumatol [online]. 2020, vol.22, n.2, e762.  Epub 01-Ago-2020. ISSN 1817-5996.

The systemic sclerosis (SS) is a disease of unknown cause, that the fact that they fix the extra-cell womb characterizes itself for a production exaggerated of molecules. The decrease in the production of nitric oxide for the microvasculature’s endothelial cells seems to play a central role in the pathogenesis of the disease. The results attained in 44 patients' study of series of cases of universe and inmunosupresor with cyclophosphamide according to therapeutic applied conduct shows of 31, with low incidence of the causes neoplastic in the death like secondary reactions and to treatment you went from motivation for the presentation of this work, that you reflected the possible relation between the systemic sclerosis and the neoplastic. It was concluded that the relation between auto-immunity and cancer can stem from an etiological common origin (genetic, hormonal, metabolic or environmental factors) or a mechanism of syndrome paraneoplastic. The disease is earthly of risk for neoplastic funny remark, the same way that the neoplastic can induce SS.

Palabras clave : systemic sclerosis; neoplastic; apoptotic.

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