Resumen

REYES PEREZ, Angélica Ma. et al. Kidney function study in HIV / AIDS patients attending at the Pedro Kourí Institute from april to september 2019. Rev. CENIC Cienc. Biol [online]. 2021, vol.52, n.3, pp.296-308.  Epub 01-Dic-2021. ISSN 2221-2450.

Chronic kidney disease (CKD) in Human Immunodeficiency Virus (HIV) infection has increased in recent years. Approximately 1% to 2% of the global population with HIV presented end-stage of CKD. The objective of this study was to assess the possible alterations of renal function in patients with HIV - acquired immunodeficiency syndrome (aids) through basic renal study. A cross-sectional analytical study was carried out in the period between April and September 2019 at the Pedro Kourí Institute. Age, gender, renal parameters (urea, creatinine, serum urates, protein excretion and Addis count), time, type and adherence to antiretroviral treatment (ARVTc) were studied in 83 CKD patients from 152 in medical attention. No probabilistic sample was considered in sequential and convenience schedule. The body mass indices of each patient were calculated to estimate renal function and the patients were staged accordingly. Percentages, means and Odds ratio were calculated with a 95 % confidence interval. The patients expelled proteins in the urine were 65,05 % and it was the predominant alteration of renal function. The 72,60% were stratified between grade I-II of CKD. Nitrogen compounds were within reference values. A direct correlation was found between age and creatinine, periods of ARVTc with age, Addis and hematies in Addis and an inverse correlation between creatinine and the theoretical Glomerular Filtration Index was observed. Proteinuria was not associated to ARVTc to which 69 patients showed good adherence. Alterations in renal function of HIV / aids patients not related to ART were found, which suggests the need for renal function monitoring in the follow-up of these patients.

Palabras clave : HIV /aids; Chronic kidney disease; proteinuria; kidney function tests.

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