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Revista Cubana de Química

versão On-line ISSN 2224-5421

Resumo

BERENGUER-RIVAS, Clara Azalea et al. Chemical composition and in- vitro antioxidant activity of extracts of Adelia ricinella L.. Rev Cub Quim [online]. 2018, vol.30, n.2, pp.191-209. ISSN 2224-5421.

Adelia ricinella L. is a plant used as analgesic, antipyretic and emenagogue. In this research, three extracts from the aerial parts of the plant were prepared by Soxhlet extraction, using 95 % ethanol, 50 % and water as solvents. The main secondary metabolites were determined from qualitative and quantitative points of view. Antioxidant activity was measured using in-vitro radical scavenging methods facing ABTS and DPPH radicals. The qualitative analysis shows alkaloids, coumarins, reducing sugars, phenols, carbohydrates and flavonoids, quantifying a higher content of the last four metabolites in the ethanol 50 % extract. Similarly, the 50 % ethanol extract was the most active, determining an average inhibitory concentration (IC50) of 0,29 ± 0,01 mg/mL against ABTS and 0,53 ± 0,02 mg/mL when faced to DPPH. These evidences show that extract prepared from A. ricinella could be useful for the treatment of diseases related by oxidative stress.

Palavras-chave : Adelia ricinella L; chemical composition; total phenols; flavonoids; antioxidant activity.

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