Abstract

GIL-FROMETA, Susana et al. Phytochemical, and antimicrobial evaluation of the essential oil and extracts of the leaves of amyris elemifera l. (yellow coaba). Rev Cub Quim [online]. 2019, vol.31, n.3, pp.427-439. ISSN 2224-5421.

Amyris elemifera L. is an aromatic plant that grows in Cuba within neither chemical nor pharmacological scientific profile, therefore; this study pretends to explore it chemical composition and antimicrobial activity. With this purpose, the ethanolic extracts (EE) was liquid-liquid fractioned with hexane (HF), ethyl acetate (EaF) and butanol fractions (BF) were obtained and chemically characterized. This extract as well as it fractions were evaluated together with the essential oil (EO) extracted by hydro distillation in their antimicrobial activity through the microdilution methodology against two bacteria, one yeast and three parasite strains. Phenols, Alkaloids, Flavonoids, Triterpenes and steroids, Cumarins, Quinones, free amino acid were detected within the EE and it fractions. The EE, HF, EaF and the EO are good anti-parasitic substances with IC50under 20µgmL-1, while BF wasn’t active. The selectivity index of EaF against Lehismania infantum classified as acceptable opening a gate to deeper future studies.

Keywords : Amyris elemifera; Screenig; essential oil; antimicrobial activity; Lehismania infantum.

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