SciELO - Scientific Electronic Library Online

 
vol.37 issue3Evaluation of technological efficiency handmade elaboration of a fresh enzymatic clotting cheese author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Services on Demand

Journal

Article

Indicators

  • Have no cited articlesCited by SciELO

Related links

  • Have no similar articlesSimilars in SciELO

Share


Tecnología Química

On-line version ISSN 2224-6185

Abstract

MONTES-GONZALEZ, Yanelys; HIDALGO-GUERRERO, Luis Carlos  and  MAYO-ABAD, Orestes. Sterilization of solutions for parenterals products. Problem analysis. RTQ [online]. 2017, vol.37, n.3, pp.367-379. ISSN 2224-6185.

The solutions for the formulation of parenteral products must be sterile before the aseptic formulation process. For this reason, different methods of sterilization referred in the literature are analyzed. Thermodynamic criteria that rule the sterilization are presented. Furthermore, previous experiences in the sterilization of solutions for the formulation of parental products in an autoclave are analyzed, that take large time of processing and only low volumes of solution can be handled. Using jacketed stirred tanks for the sterilization may solve the problem and, therefore, criteria for the design of the later that allow to process high volumes of solution for the formulation of parenteral products are shown.

Keywords : sterilization; jacketed tanks; parenterals products.

        · abstract in Spanish     · text in Spanish     · Spanish ( pdf )

 

Creative Commons License All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License