Abstract

BARRETO ARGILAGOS, Guillermo; RODRIGUEZ TORRENS, Herlinda de la Caridad  and  BARRETO RODRIGUEZ, Herlinda de la Caridad. Cooper as Inductor of Antibiotic-Resistance in Enterotoxigenic Escherichia coli. Rev. prod. anim. [online]. 2016, vol.28, n.1, pp.34-38. ISSN 2224-7920.

Cupric sulfate has been used as growth promoter in swine productions for a long time instead of the ecological risks involved. The paper had the objective of evaluating the effect of cooper as inductor of antibiotic-resistance in enterotoxigenic Escherichia coli. The reference strains A-1 (O149: K91: K88ac) and E68-I (O141: K85: K88ab) were cultivated on Mueller-Hinton Agar plates following the gradient concentration technique with ranges increased weekly from 5 till 50 mg/mL of CuSO4. Both bacteria were streaked during three weeks in parallel to controls cultured in pure medium without the inductor. At the end of the experiment the sensibility of bought groups to Gentamicin, Kanamycin, Tetracycline, Chloramphenicol, Carbenicilin and Nalidix Acid was measured. The variants treated with cooper exhibited halos referred as resistant to the antibiotics evaluated instead all the controls were sensitive. The results demonstrated the capability of cooper to develop bacterial antibiotic-resistance in vitro, another trait to be considered by producers when salts of this metal are used as growth promoters, because together with its ecological damage a lose in the effectiveness of antimicrobials employed in human and veterinary chemotherapy is developed.

Keywords : antimicrobials; environment; enteropathogens; growth promoters; swine; tolerance.

        · abstract in Spanish     · text in Spanish     · Spanish ( pdf )