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Revista Cubana de Ciencias Informáticas

versão On-line ISSN 2227-1899

Resumo

SANTIESTEBAN-TOCA, Cosme E  e  LOPEZ APARICIO, Liuben. Information retrieval system for proteins and peptides. Rev cuba cienc informat [online]. 2017, vol.11, n.3, pp.09-20. ISSN 2227-1899.

ABSTRACT The rise of research in the area of proteins has led to the development of large online databases. The main drawback of these databases is the download of individual proteins, which increases with the size of the search. However, we don´t have tools capable to extend the functionalities of search engines like PDBSelect, with respect to peptidical chains analysis and allowing to work both online or offline. In this paper, we present a tool that enables the search of peptidical chains inside the set of proteins and homologies between proteins and peptides. This tool facilitates the selection and screening of protein, among other features of interest. Extending PDBSelect functionality by allowing the search of peptide chains within the set of proteins and search homologies between proteins and peptides. The tool can work online or offline with the PDB. The analysis of a case of study helped to show how, in just six easy steps, it is possible to obtain a set of protein and peptide subsequences that allow researchers to conduct further research with these.

Palavras-chave : Bioinformatics tool; search; peptides; proteins; sequences alignment; proteins database.

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