<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>0138-6557</journal-id>
<journal-title><![CDATA[Revista Cubana de Medicina Militar]]></journal-title>
<abbrev-journal-title><![CDATA[Rev Cub Med Mil]]></abbrev-journal-title>
<issn>0138-6557</issn>
<publisher>
<publisher-name><![CDATA[Centro Nacional de Información de Ciencias MédicasEditorial Ciencias Médicas]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S0138-65572020000100003</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Monoterapia con sildenafilo en pacientes con hipertensión pulmonar grave]]></article-title>
<article-title xml:lang="en"><![CDATA[Sildenafil monotherapy in patients with severe pulmonary hypertension]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Vega Candelario]]></surname>
<given-names><![CDATA[Rodolfo]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Universidad de Ciencias Médicas de Ciego de Ávila Hospital Provincial Docente "Roberto Rodríguez Fernández" ]]></institution>
<addr-line><![CDATA[Morón, Ciego de Ávila ]]></addr-line>
<country>Cuba</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>03</month>
<year>2020</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>03</month>
<year>2020</year>
</pub-date>
<volume>49</volume>
<numero>1</numero>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://scielo.sld.cu/scielo.php?script=sci_arttext&amp;pid=S0138-65572020000100003&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.sld.cu/scielo.php?script=sci_abstract&amp;pid=S0138-65572020000100003&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.sld.cu/scielo.php?script=sci_pdf&amp;pid=S0138-65572020000100003&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[RESUMEN  Introducción:  El tratamiento con inhibidores de la fosfodiesterasa 5 a pacientes con cardiopatías adquiridas y congénitas, con hipertensión pulmonar, puede mejorar la calidad y pronóstico de vida, tanto en cardiopatías quirúrgicas como no quirúrgicas, con hipertensión pulmonar grave.  Objetivos:  Analizar los resultados de la monoterapia con sildenafilo en pacientes quirúrgicos y no quirúrgicos, con cardiopatías congénitas y adquiridas e hipertensión pulmonar grave.  Método:  Estudio descriptivo en 60 pacientes que recibieron sildenafilo para hipertensión arterial pulmonar grave, secundaria a cardiopatías adquiridas izquierdas, congénitas. Se observó: dosis, duración del tratamiento, tolerancia, evolución clínica y ecocardiográfica, clase funcional y tratamiento quirúrgico según resultados del cateterismo cardiaco.  Resultados:  En el período entre diciembre de 2017 a diciembre de 2018 se operaron con hipertensión arterial pulmonar grave, 20 enfermos con trastornos valvulares cardíacos izquierdos, 8 congénitos y 3 tumores cardíacos primarios, con administración de sildenafilo en dosis de 100 a 150 miligramos diarios. Hubo otros 29 pacientes con cardiopatías, que aunque no eran quirúrgicos, mejoraron su calidad y pronóstico de vida.  Conclusiones:  Resultó útil la indicación de sildenafilo, para mejorar la calidad y el pronóstico de vida, tanto en pacientes quirúrgicos como no quirúrgicos con cardiopatías e hipertensión pulmonar grave.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[ABSTRACT  Introduction:  Treatment with phosphodiesterase 5 inhibitors in patients with acquired and congenital heart disease, with pulmonary hypertension, can improve the quality and prognosis of life, both in surgical and non-surgical heart disease, with severe pulmonary hypertension.  Objectives:  To analyze the results of sildenafil monotherapy in surgical and non-surgical patients, with congenital and acquired heart disease and severe pulmonary hypertension.  Method:  Descriptive study in 60 patients who received sildenafil for severe pulmonary arterial hypertension, secondary to congenital left acquired heart disease. It was observed: dose, duration of treatment, tolerance, clinical and echocardiographic evolution, functional class and surgical treatment according to cardiac catheterization results.  Results:  In the period between December 2017 and December 2018, 20 patients with left heart valvular disorders, 8 congenital and 3 primary cardiac tumors, with sildenafil daily administration doses of 100 to 150 milligrams, were operated with severe pulmonary arterial hypertension. There were 29 other patients with heart disease, which although they were not surgical, improved their quality and prognosis of life.  Conclusions:  The prescription of sildenafil was useful to improve the quality and prognosis of life, both in surgical and non-surgical patients with heart disease and severe pulmonary hypertension.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[cardiopatía congénita]]></kwd>
<kwd lng="es"><![CDATA[cardiopatía adquirida]]></kwd>
<kwd lng="es"><![CDATA[hipertensión pulmonar]]></kwd>
<kwd lng="es"><![CDATA[monoterapia con sildenafilo]]></kwd>
<kwd lng="es"><![CDATA[calidad de vida]]></kwd>
<kwd lng="es"><![CDATA[pronóstico de vida]]></kwd>
<kwd lng="en"><![CDATA[congenital heart disease]]></kwd>
<kwd lng="en"><![CDATA[acquired heart disease]]></kwd>
<kwd lng="en"><![CDATA[pulmonary hypertension]]></kwd>
<kwd lng="en"><![CDATA[monotherapy with sildenafil, quality of life]]></kwd>
<kwd lng="en"><![CDATA[life forecast]]></kwd>
</kwd-group>
</article-meta>
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