<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>0138-6557</journal-id>
<journal-title><![CDATA[Revista Cubana de Medicina Militar]]></journal-title>
<abbrev-journal-title><![CDATA[Rev Cub Med Mil]]></abbrev-journal-title>
<issn>0138-6557</issn>
<publisher>
<publisher-name><![CDATA[Centro Nacional de Información de Ciencias MédicasEditorial Ciencias Médicas]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S0138-65572021000400004</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Caracterización de pacientes con enfermedad pulmonar obstructiva crónica en la unidad de cuidados intensivos]]></article-title>
<article-title xml:lang="en"><![CDATA[Characterization of patients with chronic obstructive pulmonary diseases at the Intensive Care Unit]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[García Gómez]]></surname>
<given-names><![CDATA[Alberto]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Ramírez Cruz]]></surname>
<given-names><![CDATA[Narciso]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Agüero Carbonell]]></surname>
<given-names><![CDATA[Yaqueline]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Hernández Torres]]></surname>
<given-names><![CDATA[Alexis]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Massó Vicet]]></surname>
<given-names><![CDATA[Yusel]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Martínez Llano]]></surname>
<given-names><![CDATA[Yamilka]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Hospital Militar Central &#8220;Dr. Carlos J. Finlay&#8221;  ]]></institution>
<addr-line><![CDATA[ La Habana]]></addr-line>
<country>Cuba</country>
</aff>
<aff id="Af2">
<institution><![CDATA[,Hospital Clínica de 42  ]]></institution>
<addr-line><![CDATA[ La Habana]]></addr-line>
<country>Cuba</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>12</month>
<year>2021</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>12</month>
<year>2021</year>
</pub-date>
<volume>50</volume>
<numero>4</numero>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://scielo.sld.cu/scielo.php?script=sci_arttext&amp;pid=S0138-65572021000400004&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.sld.cu/scielo.php?script=sci_abstract&amp;pid=S0138-65572021000400004&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.sld.cu/scielo.php?script=sci_pdf&amp;pid=S0138-65572021000400004&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[RESUMEN  Introducción: La enfermedad pulmonar obstructiva crónica se caracteriza por la limitación del flujo aéreo, no completamente reversible, progresiva y asociada a respuesta inflamatoria anormal de los pulmones.  Objetivos: Caracterizar a pacientes con antecedentes de enfermedad pulmonar obstructiva crónica, ingresados en cuidados intensivos.  Métodos: Se realizó un estudio descriptivo, retrospectivo en una serie de 347 pacientes con enfermedad pulmonar obstructiva crónica ingresados en cuidados intensivos. Se estudiaron las variables edad, sexo, causa de ingreso, estado al egreso, valor de la escala APACHE II al ingreso, ventilación mecánica invasiva, traqueostomía, y causa directa de muerte según necropsias realizadas. Se calcularon distribuciones de frecuencia absoluta y relativa, medidas de tendencia central y para comparación, las pruebas de ji cuadrado y t de Student, con un nivel de significación del 5 %.  Resultados: La edad media fue de 72,1 ± 8,2 años. Predominaron el sexo femenino (52,7 %) y el grupo de edad de 60-79 años (67,1 %). La proporción sexo femenino/ masculino fue de 1,1:1,0. Egresaron fallecidos 64,8 % de los pacientes. Hubo diferencias significativas entre la edad media de los fallecidos y los vivos (p = 0,001). La causa de ingreso clínico tuvo el mayor número de ingresos (86,7 %). La media del valor del APACHE II fue superior en los fallecidos (21,0 vs. 15,2). El 81,3 % de los pacientes recibió ventilación mecánica, y al 17,3 % se le realizó traqueostomía. La principal causa de muerte fue la bronconeumonía bacteriana (67,2 %).  Conclusiones:  Los pacientes con enfermedad pulmonar obstructiva crónica ingresados en la unidad de cuidados intensivos tienen alta mortalidad y está asociada a tres principales causas directas de muertes: bronconeumonía bacteriana, tromboembolismo pulmonar y el choque séptico.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[ABSTRACT  Introduction:  COPD is characterized by limitation of the airflow, progressive, partially reversible and associated to an abnormal inflammatory responsive of the lungs.  Objective: To characterize patients with COPD admitted at the Intensive Care Unit.  Methods: A descriptive, retrospective study was carried out in a series of 347 patients with chronic obstructive pulmonary disease admitted to intensive care. The variables age, sex, cause of admission, discharge status, APACHE II scale value at admission, invasive mechanical ventilation, tracheostomy, and direct cause of death according to autopsies performed were studied. Absolute and relative frequency distributions, measures of central tendency, and for comparison, the chi-square and Student's t tests were calculated, with a significance level of 5%.  Results: The mean age was of 72,1 ± 8,2 years. The female sex (52.7%) and the age group of 60-79 years (67.1%) predominated. The female / male sex ratio was 1.1: 1.0. 64.8% of the patients were discharged dead. There were significant differences between the mean age of the deceased and the living (p = 0.001). The cause of clinical admission had the highest number of admissions (86.7%). The mean APACHE II value was higher in the deceased (21.0 vs. 15.2). 81.3% of the patients received mechanical ventilation, and 17.3% underwent a tracheostomy. The main cause of death was bacterial bronchopneumonia (67.2%).  Conclusions: Patients with chronic obstructive pulmonary disease admitted to the intensive care unit have high mortality and it is associated with three main direct causes of death: bacterial bronchopneumonia, pulmonary thromboembolism and septic shock.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[enfermedad pulmonar obstructiva crónica]]></kwd>
<kwd lng="es"><![CDATA[unidad de cuidados intensivos]]></kwd>
<kwd lng="es"><![CDATA[mortalidad]]></kwd>
<kwd lng="en"><![CDATA[chronic obstruct pulmonary disease]]></kwd>
<kwd lng="en"><![CDATA[intensive care unit]]></kwd>
<kwd lng="en"><![CDATA[mortality]]></kwd>
</kwd-group>
</article-meta>
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