<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>1025-0255</journal-id>
<journal-title><![CDATA[Revista Archivo Médico de Camagüey]]></journal-title>
<abbrev-journal-title><![CDATA[AMC]]></abbrev-journal-title>
<issn>1025-0255</issn>
<publisher>
<publisher-name><![CDATA[Universidad de Ciencias Médicas de Camagüey]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S1025-02552019000600802</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Cartílago y gonartrosis]]></article-title>
<article-title xml:lang="en"><![CDATA[Cartilage and knee osteoarthritis]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Alvarez-López]]></surname>
<given-names><![CDATA[Alejandro]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Fuentes-Véjar]]></surname>
<given-names><![CDATA[Rodrigo]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Soto-Carrasco]]></surname>
<given-names><![CDATA[Sergio Ricardo]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Nguyen-Pham]]></surname>
<given-names><![CDATA[Tuan]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[García-Lorenzo]]></surname>
<given-names><![CDATA[Yenima de la Caridad]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Universidad de Ciencias Médicas de Camagüey Hospital Universitario Manuel Ascunce Domenech Servicio de Ortopedia y Traumatología]]></institution>
<addr-line><![CDATA[Camagüey ]]></addr-line>
<country>Cuba</country>
</aff>
<aff id="Af2">
<institution><![CDATA[,Universidad Católica de la Santísima Concepción Facultad de Medicina Servicio de Cirugía General]]></institution>
<addr-line><![CDATA[Concepción ]]></addr-line>
<country>Chile</country>
</aff>
<aff id="Af3">
<institution><![CDATA[,Hospital de Amistad entre Vietnam y Cuba Servicio de Ortopedia y Traumatología ]]></institution>
<addr-line><![CDATA[Dong Hoy ]]></addr-line>
<country>Viet Nam</country>
</aff>
<aff id="Af4">
<institution><![CDATA[,Universidad de Ciencias Médicas de Camagüey Policlínico Universitario Tula Aguilera Departamento de Medicina General Integral]]></institution>
<addr-line><![CDATA[Camagüey ]]></addr-line>
<country>Cuba</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>12</month>
<year>2019</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>12</month>
<year>2019</year>
</pub-date>
<volume>23</volume>
<numero>6</numero>
<fpage>802</fpage>
<lpage>813</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://scielo.sld.cu/scielo.php?script=sci_arttext&amp;pid=S1025-02552019000600802&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.sld.cu/scielo.php?script=sci_abstract&amp;pid=S1025-02552019000600802&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.sld.cu/scielo.php?script=sci_pdf&amp;pid=S1025-02552019000600802&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[RESUMEN  Fundamento: el cartílago articular es un tejido avascular, aneural y alinfático que desempeña un importante papel en la articulación, su afección más frecuente es la de tipo degenerativa.  Objetivo:  actualizar los conocimientos sobre el cartílago articular normal, envejecido y con cambios degenerativos.  Métodos: la búsqueda y análisis de la información se realizó en un periodo de tres meses (primero de octubre al 31 de diciembre de 2018) y se emplearon las siguientes palabras: cartilage AND osteoarthritis, cartilage AND knee osteoarthritis, cartilage a partir de la información obtenida se realizó una revisión bibliográfica de un total de 164 artículos publicados en las bases de datos PubMed, Hinari, SciELO y Medline mediante el gestor de búsqueda y administrador de referencias EndNote, de ellos se utilizaron 50 citas seleccionadas para realizar la revisión, de ellas 48 de los últimos cinco años.  Resultados: se mencionan los aspectos macro y microscópicos del tejido, así como su organización por zonas y áreas. Se describen los cambios que ocurren en el proceso degenerativo a diferentes niveles y en el envejecimiento.  Conclusiones: el cartílago articular es la estructura anatómica más afectada en la articulación por el proceso degenerativo. Se encuentra organizado por zonas y áreas, las que se afectan a medida que avanza la enfermedad. El origen de la destrucción del cartílago es enzimático y repercute en las demás estructuras como el tejido sinovial y hueso subcondral. Es importante conocer las diferencias entre el envejecimiento y la afección degenerativa de este tejido.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[ABSTRACT  Background:  articular cartilage is an important avascular, alinphatic and aneural tissue in joints, it is mainly affected by degenerative disease.  Objective:  to update knowledge about normal, aging and degenerative articular cartilage.  Methods:  a three months research and analysis were conducted from October 1st, 2018 to December 31th, 2018. Our review included 164 articles published in PubMed, Hinari, SciELO and Medline databases by using EndNote. The words used were cartilage AND osteoarthritis, cartilage AND knee osteoarthritis, cartilage. Fifty citations were selected, 48 of all them within the last five years, were used to write the present paper.  Results:  macro and microscopic features of articular cartilage were mentioned as well as its organization in zones and areas. Degenerative process was described at different levels, and in aging.  Conclusions:  articular cartilage is the most affected tissue in osteoarthritis. Cartilage is organized by zones and areas which are affected as degenerative disease progresses. The start point of osteoarthritis is enzymatic and gradually affects synovial tissue and sub-chondral bone. It is important to know the main differences between aging and degenerative cartilages.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[CARTÍLAGO ARTICULAR]]></kwd>
<kwd lng="es"><![CDATA[OSTEOARTRITIS/enzimología]]></kwd>
<kwd lng="es"><![CDATA[ARTROPATÍAS]]></kwd>
<kwd lng="es"><![CDATA[OSTEOARTRITIS DE LA RODILLA]]></kwd>
<kwd lng="es"><![CDATA[MEMBRANA SINOVIAL]]></kwd>
<kwd lng="en"><![CDATA[CARTILAGE, ARTICULAR]]></kwd>
<kwd lng="en"><![CDATA[OSTEOARTHRITIS/enzymology]]></kwd>
<kwd lng="en"><![CDATA[JOINT DISEASES]]></kwd>
<kwd lng="en"><![CDATA[OSTEOARTHRITIS, KNEE]]></kwd>
<kwd lng="en"><![CDATA[SYNOVIAL MEMBRANE]]></kwd>
</kwd-group>
</article-meta>
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