<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>1028-4818</journal-id>
<journal-title><![CDATA[Multimed]]></journal-title>
<abbrev-journal-title><![CDATA[Multimed]]></abbrev-journal-title>
<issn>1028-4818</issn>
<publisher>
<publisher-name><![CDATA[Centro Provincial de Información de Ciencias Médicas]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S1028-48182020000400836</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Parámetros clínicos, bioquímicos y metabólicos predictores de complicaciones micro y macrovasculares en diabéticos tipo 2]]></article-title>
<article-title xml:lang="en"><![CDATA[Clinical, biochemical and metabolic parameters predictive of micro and macrovascular complications in type 2 diabetics]]></article-title>
<article-title xml:lang="pt"><![CDATA[Parâmetros clínicos, bioquímicos e metabólicos preditivos de complicações micro e macrovasculares em diabéticos tipo 2]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Sarduy Rodríguez.]]></surname>
<given-names><![CDATA[Ariel]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Cruz Manzano.]]></surname>
<given-names><![CDATA[Elio]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Milanés Ojea.]]></surname>
<given-names><![CDATA[María Rosario]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Mompié Gómez.]]></surname>
<given-names><![CDATA[Gonzalo Rafael]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Universidad de Ciencias Médicas de Granma Filial de Ciencias Médicas ]]></institution>
<addr-line><![CDATA[Bayamo Granma]]></addr-line>
<country>Cuba</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>08</month>
<year>2020</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>08</month>
<year>2020</year>
</pub-date>
<volume>24</volume>
<numero>4</numero>
<fpage>836</fpage>
<lpage>852</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://scielo.sld.cu/scielo.php?script=sci_arttext&amp;pid=S1028-48182020000400836&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.sld.cu/scielo.php?script=sci_abstract&amp;pid=S1028-48182020000400836&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.sld.cu/scielo.php?script=sci_pdf&amp;pid=S1028-48182020000400836&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[RESUMEN  Introducción:  la diabetes mellitus (DM) es una enfermedad endocrino - metabólica, vascular, crónica, producida por una interacción variable de factores genéticos y ambientales. Actualmente la DM2 es considerada por algunos autores como pandémica, sin la existencia de signos de reducción de las tasas de incidencia.  Objetivo:  identificar los parámetros clínicos, bioquímicos y metabólicos predictores de complicaciones micro y macrovasculares en personas con diabetes mellitus tipo 2.  Método:  se realizó un estudio analítico de tipo casos y controles con pacientes ingresados en el Centro de Atención al Diabético de Bayamo (CAD), Granma, desde el año 2010 al 2017, 81 con alguna complicación microvascular, 40 con alguna complicación macrovascular y 162 sin ninguna complicación.  Resultados:  en el análisis univariado se observó que el tiempo de evolución de la enfermedad y la HTA descontrolada fueron los factores de riesgo para el desarrollo de una complicación microvascular, mientras que a estas se le unieron el tabaquismo y le hipercolesterolemia como factores de riesgo para el desarrollo de complicaciones macrovasculares. Las variables que mostraron una relación independiente con el riesgo de desarrollar alguna complicación microvascular fueron el tiempo de evolución de la enfermedad y la HTA descontrolada, mientras que para el desarrollo de complicaciones macrovasculares fueron el tiempo de evolución de la enfermedad y el tabaquismo.  Conclusiones:  el tiempo de evolución de la diabetes y la HTA descontrolada y el tiempo de evolución de la enfermedad y el tabaquismo se asocian de forma independiente con la aparición de complicaciones microvasculares y macrovasculates respectivamente.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[ABSTRACT  Introduction:  diabetes mellitus (DM) is an endocrine-metabolic, vascular, chronic disease, produced by a variable interaction of genetic and environmental factors. Currently DM2 is considered by some authors as pandemic, without the existence of signs of reduction of incidence rates.  Objective:  to identify clinical, biochemical and metabolic parameters predictors of micro and macrovascular complications in people with type 2 diabetes mellitus.  Method:  an analytical case and control study was conducted with patients admitted to the Bayamo Diabetic Care Center (CAD), Granma, from 2010 to 2017, 81 with some microvascular complications, 40 with some macrovascular complications and 162 without any complications.  Results:  the univariate analysis found that disease progression time and uncontrolled HTA were the risk factors for the development of a microvascular complication, while these were joined by smoking and hypercholesterolemia as risk factors for the development of macrovascular complications. The variables that showed an independent relationship with the risk of developing some microvascular complications were the time of disease evolution and uncontrolled HTA, while for the development of macrovascular complications were the time of disease evolution and smoking.  Conclusions:  the time of evolution of diabetes and uncontrolled HTA and the time of disease and smoking evolution are independently associated with the emergence of microvascular and macrovasculate complications respectively.]]></p></abstract>
<abstract abstract-type="short" xml:lang="pt"><p><![CDATA[RESUMO  Introdução:  diabetes mellitus (DM) é uma doença endócrina-metabólica, vascular, crônica, produzida por uma interação variável de fatores genéticos e ambientais. Atualmente o DM2 é considerado por alguns autores como pandemia, sem a existência de sinais de redução das taxas de incidência.  Objetivo:  identificar preditores de parâmetros clínicos, bioquímicos e metabólicos de complicações micro e macrovasculares em pessoas com diabetes mellitus tipo 2.  Método:  estudo analítico de caso e controle foi realizado com pacientes internados no Centro de Atendimento Diabético Bayamo (CAD), Granma, de 2010 a 2017, 81 com algumas complicações microvasculares, 40 com algumas complicações macrovasculares e 162 sem complicações.  Resultados:  a análise univariada constatou que o tempo de progressão da doença e o HTA descontrolado foram os fatores de risco para o desenvolvimento de uma complicação microvascular, enquanto estes foram acompanhados pelo tabagismo e hipercolesterolemia como fatores de risco para o desenvolvimento de complicações macrovasculares. As variáveis que apresentaram relação independente com o risco de desenvolver algumas complicações microvasculares foram o tempo de evolução da doença e HTA descontrolada, enquanto para o desenvolvimento de complicações macrovasculares foi o tempo de evolução da doença e tabagismo.  Conclusões:  o tempo de evolução do diabetes e do HTA descontrolado e o tempo de evolução da doença e do tabagismo estão independentemente associados ao surgimento de complicações microvasculares e macrovasculadas, respectivamente.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[Diabetes mellitus tipo 2]]></kwd>
<kwd lng="es"><![CDATA[Complicaciones microvasculares]]></kwd>
<kwd lng="es"><![CDATA[Complicaciones macrovasculares]]></kwd>
<kwd lng="es"><![CDATA[Factores de riesgo]]></kwd>
<kwd lng="en"><![CDATA[Diabetes mellitus type 2]]></kwd>
<kwd lng="en"><![CDATA[Microvascular complications]]></kwd>
<kwd lng="en"><![CDATA[Macrovascular complications]]></kwd>
<kwd lng="en"><![CDATA[Risk factors]]></kwd>
<kwd lng="pt"><![CDATA[Diabetes mellitus tipo 2]]></kwd>
<kwd lng="pt"><![CDATA[Complicações microvasculares]]></kwd>
<kwd lng="pt"><![CDATA[Complicações macrovasculares]]></kwd>
<kwd lng="pt"><![CDATA[Fatores de risco]]></kwd>
</kwd-group>
</article-meta>
</front><back>
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