<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>0034-7531</journal-id>
<journal-title><![CDATA[Revista Cubana de Pediatría]]></journal-title>
<abbrev-journal-title><![CDATA[Rev Cubana Pediatr]]></abbrev-journal-title>
<issn>0034-7531</issn>
<publisher>
<publisher-name><![CDATA[Centro Nacional de Información de Ciencias MédicasEditorial Ciencias Médicas]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S0034-75312021000400018</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Síndrome inflamatorio multisistémico en niños asociado a COVID-19]]></article-title>
<article-title xml:lang="en"><![CDATA[Multisystemic Inflammatory Syndrome in Children Associated With COVID-19]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Pérez Torres]]></surname>
<given-names><![CDATA[Edilberto]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
<xref ref-type="aff" rid="Aaf"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Ríos Urpay]]></surname>
<given-names><![CDATA[Eddy Percy]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Hospital Nacional Ramiro Priale Priale  ]]></institution>
<addr-line><![CDATA[ Huancayo]]></addr-line>
<country>Perú</country>
</aff>
<aff id="Af2">
<institution><![CDATA[,Universidad Nacional del Centro del Perú  ]]></institution>
<addr-line><![CDATA[ Huancayo]]></addr-line>
<country>Peru</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>12</month>
<year>2021</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>12</month>
<year>2021</year>
</pub-date>
<volume>93</volume>
<numero>4</numero>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://scielo.sld.cu/scielo.php?script=sci_arttext&amp;pid=S0034-75312021000400018&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.sld.cu/scielo.php?script=sci_abstract&amp;pid=S0034-75312021000400018&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.sld.cu/scielo.php?script=sci_pdf&amp;pid=S0034-75312021000400018&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[RESUMEN  Introducción: La afectación de la COVID-19 en niños es leves o asintomática, en la mayoría de los casos, pero un pequeño porcentaje presenta enfermedades graves que requieren ingreso en la unidad de cuidados intensivos pediátricos, uno de ellos es el síndrome inflamatorio multisistémico en niños asociado a COVID-19, caracterizado por fiebre, reactantes de fase aguda elevado y afectación de varios órganos.  Objetivo:  Informar dos casos con síndrome inflamatorio multisistémico en niños asociado a COVID-19, en la Ciudad de Huancayo - Perú.  Presentación de los casos:  Caso 1: paciente varón de 3 años, con un tiempo de enfermedad de 12 días que inicio con síntomas de vías respiratorias superiores y fiebre por tres días y con malestar general y 4 días antes del ingreso presenta fiebre en forma persistente, dolor abdominal tipo cólico asociado a vómitos, también inicia con exantema purpúrica en miembros inferiores. Cuenta como antecedente padre con prueba de PCR - RT para COVID-19 positivo 3 semanas antes del ingreso del menor. Caso 2: paciente varón de 10 años, con antecedente de neumonía por COVID-19, 15 días antes del ingreso, acude con un tiempo de enfermedad de 3 días caracterizado por fiebre, fatiga y palpitaciones que se exacerban con la actividad física.  Conclusión: El síndrome inflamatorio multisistémico en niños asociado a COVID-19 es una enfermedad nueva que requiere un manejo multidisciplinario en una unidad de cuidados intensivos pediátricos.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[ABSTRACT  Introduction: The condition of COVID-19 in children is mild or asymptomatic in most cases, but a small percentage has serious diseases that require admission to the pediatric intensive care unit, one of them is the multisystemic inflammatory syndrome in children associated with COVID-19, characterized by fever, high acute phase reactants and involvement of various organs.  Objective:  To report two cases with multisystemic inflammatory syndrome in children associated with COVID-19, in Huancayo City - Peru.  Case report:  Case 1: A 3-year-old male patient had 12-day illness period that began with upper respiratory symptoms, fever for three days, general discomfort and 4 days before admission, he showed with persistent fever, colicky abdominal pain associated with vomiting, also he had a purpuric rash on the lower limbs. As a background, his father tested positive for the PCR-RT test for COVID-19, 3 weeks before the child's admission. Case 2: A 10-year-old male patient, with a history of COVID-19 pneumonia, 15 days before admission, he had a 3-day illness period characterized by fever, fatigue and palpitations that exacerbated by physical activity.  Conclusions:  The multisystemic inflammatory syndrome in children associated with COVID-19 is a new disease that requires multidisciplinary management in a pediatric intensive care unit.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[síndrome inflamatorio multisistémico]]></kwd>
<kwd lng="es"><![CDATA[niños]]></kwd>
<kwd lng="es"><![CDATA[COVID-19]]></kwd>
<kwd lng="en"><![CDATA[multisystemic inflammatory syndrome]]></kwd>
<kwd lng="en"><![CDATA[children]]></kwd>
<kwd lng="en"><![CDATA[COVID-19]]></kwd>
</kwd-group>
</article-meta>
</front><back>
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