<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>0864-2176</journal-id>
<journal-title><![CDATA[Revista Cubana de Oftalmología]]></journal-title>
<abbrev-journal-title><![CDATA[Rev Cubana Oftalmol]]></abbrev-journal-title>
<issn>0864-2176</issn>
<publisher>
<publisher-name><![CDATA[Editorial Ciencias Médicas]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S0864-21762019000400004</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Caracterización de la membrana basal, los plexos nerviosos y el grosor corneal mediante microscopia confocal en pacientes diabéticos]]></article-title>
<article-title xml:lang="en"><![CDATA[Characterization of basal membrane, nervous plexus and corneal thickness by confocal microscopy in diabetic patients]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Gutiérrez Castillo]]></surname>
<given-names><![CDATA[Marietta]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Castillo Pérez]]></surname>
<given-names><![CDATA[Alexeide de la C.]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Ramos López]]></surname>
<given-names><![CDATA[Meysi]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Pérez Parra]]></surname>
<given-names><![CDATA[Zaadia]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Ramos Pereira]]></surname>
<given-names><![CDATA[Yanay]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Barroso Lorenzo]]></surname>
<given-names><![CDATA[Raúl]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Instituto Cubano de Oftalmología &#8220;Ramón Pando Ferrer&#8221;  ]]></institution>
<addr-line><![CDATA[La Habana ]]></addr-line>
<country>Cuba</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>12</month>
<year>2019</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>12</month>
<year>2019</year>
</pub-date>
<volume>32</volume>
<numero>4</numero>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://scielo.sld.cu/scielo.php?script=sci_arttext&amp;pid=S0864-21762019000400004&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.sld.cu/scielo.php?script=sci_abstract&amp;pid=S0864-21762019000400004&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.sld.cu/scielo.php?script=sci_pdf&amp;pid=S0864-21762019000400004&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[RESUMEN  Objetivo:  Identificar las características morfológicas y morfométricas de las capas de la córnea mediante microscopia confocal en pacientes diabéticos.  Métodos:  Se realizó un estudio descriptivo, comparativo, en 90 ojos, 60 de ellos pertenecientes a pacientes diabéticos (30 tipo 1 y 30 tipo 2) y 30 a pacientes supuestamente sanos. El estudio se realizó en el Instituto Cubano de Oftalmología &#8220;Ramón Pando Ferrer&#8221; entre enero del año 2012 y enero de 2017.  Resultados:  El espesor del epitelio, el estroma y el endotelio corneal fue mayor en los ojos de diabéticos tipo 1 con una media de 54,6; 506,7 y 26,7 micras respectivamente. La membrana basal epitelial se observó en el 20 % de los ojos de pacientes con diabetes mellitus tipo 1, y en el 10 % de los diabéticos tipo 2. El grupo de diabéticos tipo 1 mostró uno y dos plexos nerviosos por campo de microscopia confocal para el 33,3 % cada uno. En los diabéticos tipo 2, predominó un plexo nervioso (40 %) y en pacientes sanos predominaron 4 plexos nerviosos (66,7 %). Ambos grupos de pacientes diabéticos presentaron plexos verticales tortuosos (40 % y 53,3 % respectivamente) y plexos nerviosos oblicuos en el grupo de pacientes supuestamente sanos (80 %).  Conclusiones:  El estudio de la córnea por microscopia confocal en pacientes diabéticos evidencia mayor espesor corneal total y por capas, membrana basal visible, disminución del plexo nervioso sub-basal con disposición vertical y tortuosidad de las fibras.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[ABSTRACT  Objective:  To identify the morphological and morphometric characteristics of the corneal layers by confocal microscopy in diabetic patients.  Methods:  A descriptive and comparative study was carried out in 90 eyes, 60 of which belonged to diabetic patients (30 type 1 and 30 type 2) and 30 to supposedly healthy patients. The study was conducted at Ramón Pando Ferrer Cuban Institute of Ophthalmology, between January 2012 and January 2017.  Results:  Epithelial thickness, stroma and corneal endothelium was greater in the eyes of type 1 diabetics with a mean of 54.6, 506.7 and 26.7 microns, respectively. The epithelial basement membrane was observed in 20% of the eyes of patients with type 1 diabetes mellitus, and in 10% of type 2 diabetics. The group of type 1 diabetics showed one and two nerve plexuses per confocal microscopy field for 33.3% each. In type 2 diabetics, one nerve plexus (40%) predominated, while in healthy patients, four nerve plexuses (66.7%) predominated. Both groups of diabetic patients presented tortuous vertical plexuses (40% and 53.3%, respectively) and oblique nerve plexuses in the group of supposedly healthy patients (80%).  Conclusions:  The study of the cornea by confocal microscopy in diabetic patients showed greater total and layered corneal thicknesses, visible basal membrane, decrease in the sub-basal nerve plexus with vertical arrangement, and tortuous fiber.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[Microscopia confocal]]></kwd>
<kwd lng="es"><![CDATA[córnea]]></kwd>
<kwd lng="es"><![CDATA[diabetes mellitus]]></kwd>
<kwd lng="en"><![CDATA[Confocal microscopy]]></kwd>
<kwd lng="en"><![CDATA[cornea]]></kwd>
<kwd lng="en"><![CDATA[diabetes mellitus]]></kwd>
</kwd-group>
</article-meta>
</front><back>
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