<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>0864-2176</journal-id>
<journal-title><![CDATA[Revista Cubana de Oftalmología]]></journal-title>
<abbrev-journal-title><![CDATA[Rev Cubana Oftalmol]]></abbrev-journal-title>
<issn>0864-2176</issn>
<publisher>
<publisher-name><![CDATA[Editorial Ciencias Médicas]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S0864-21762020000100002</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Queratoplastia penetrante con y sin terapia antiviral en la queratopatía herpética]]></article-title>
<article-title xml:lang="en"><![CDATA[Penetrating keratoplasty with and without antiviral therapy in herpetic keratopathy]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Mokey Castellanos]]></surname>
<given-names><![CDATA[Miguel O.]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Álvarez Rivero]]></surname>
<given-names><![CDATA[Mirta Beatriz]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Hospital Clínico Quirúrgico &#8220;Hermanos Ameijeiras&#8221;  ]]></institution>
<addr-line><![CDATA[La Habana ]]></addr-line>
<country>Cuba</country>
</aff>
<aff id="Af2">
<institution><![CDATA[,Hospital Pediátrico Docente &#8220;Borras-Marfán&#8221;  ]]></institution>
<addr-line><![CDATA[La Habana ]]></addr-line>
<country>Cuba</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>03</month>
<year>2020</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>03</month>
<year>2020</year>
</pub-date>
<volume>33</volume>
<numero>1</numero>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://scielo.sld.cu/scielo.php?script=sci_arttext&amp;pid=S0864-21762020000100002&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.sld.cu/scielo.php?script=sci_abstract&amp;pid=S0864-21762020000100002&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.sld.cu/scielo.php?script=sci_pdf&amp;pid=S0864-21762020000100002&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[RESUMEN  Objetivo:  Identificar el resultado óptico o terapéutico de la queratoplastia penetrante en pacientes con queratopatía herpética.  Métodos:  Se realizó una investigación descriptiva, transversal, donde se expusieron los resultados del alcance de la queratoplastia penetrante por queratopatía herpética, operados en el Hospital Clínico Quirúrgico &#8220;Hermanos Ameijeiras&#8221;, de La Habana.  Resultados:  La muestra fue de 33 queratoplastias penetrantes. Con fines ópticos sumaron 24 (72,7 %) y tectónicas 9 (27,3 %). En 5 de estas la agudeza visual fue menor o igual a 0,3. En el total de la muestra, 9 opacificaron, 11 sufrieron complicaciones posquirúrgicas, 8 recurrieron en queratoplastias penetrantes ópticas y 6 en queratoplastias penetrantes terapéuticas. Se rechazaron 7 queratoplastias penetrantes ópticas (33,3 %) y 4 queratoplastias penetrantes terapéuticas (4 %). Presentaron complicaciones 5 (25 %) con queratoplastias penetrantes ópticas y 6 (55,6 %) con queratoplastias penetrantes terapéuticas. En el posquirúrgico 22 (66,6 %) tenían agudeza visual mayor o igual a 0,3 (p= 0,0000).  Conclusiones:  La inactividad de la enfermedad viral corneal beneficia el pronóstico del injerto por queratopatía herpética en las opacidades de las queratoplastias con fines ópticos. Queda demostrado que el uso de antivirales pre y posoperatorios disminuye la recidiva de la enfermedad herpética sobre el injerto y el rechazo, al lograr mejor agudeza visual y mayor viabilidad. La severidad inflamatoria posquirúrgica se asocia con la enfermedad viral activa o afección de origen inmune al realizar el trasplante, conexos a las complicaciones post queratoplastia.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[ABSTRACT  Objective:  Identify the optical or therapeutic outcome of penetrating keratoplasty in patients with herpetic keratopathy.  Methods:  A descriptive cross-sectional study was conducted in which a presentation was made of the results of the scope of penetrating keratoplasties for herpetic keratopathy performed at Hermanos Ameijeiras Clinical Surgical Hospital in Havana.  Results:  The sample was 33 penetrating keratoplasties: 24 optical (72.7%) and 9 tectonic (27.3%). Visual acuity was lower than or equal to 0.3 in 5 of them. Of the total sample, 9 opacified, 11 had postoperative complications, 8 recurred in optical penetrating keratoplasties, and 6 in therapeutic penetrating keratoplasties. Rejection occurred in 7 optical penetrating keratoplasties (33.3%) and 4 therapeutic penetrating keratoplasties (4%). Complications were observed in 5 (25%) optical penetrating keratoplasties and 6 (55.6%) therapeutic penetrating keratoplasties. In the postoperative period 22 (66.6%) had a visual acuity greater than or equal to 0.3 (p= 0.0000).  Conclusions:  Inactivity of corneal viral disease benefits the prognosis of grafting due to herpetic keratopathy in opacities of optical keratoplasties. Pre- and postoperative antivirals were found to reduce the recurrence of herpetic disease on the graft and rejection, achieving better visual acuity and greater viability. Postoperative inflammatory severity is associated to an active viral disease or an immune disorder at the time of the grafting resulting in post keratoplasty complications.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[Queratopatía herpética]]></kwd>
<kwd lng="es"><![CDATA[queratoplastia penetrante, trasplante corneal penetrante]]></kwd>
<kwd lng="en"><![CDATA[Herpetic keratopathy]]></kwd>
<kwd lng="en"><![CDATA[penetrating keratoplasty]]></kwd>
<kwd lng="en"><![CDATA[penetrating corneal transplant]]></kwd>
</kwd-group>
</article-meta>
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