<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>1027-2852</journal-id>
<journal-title><![CDATA[Biotecnología Aplicada]]></journal-title>
<abbrev-journal-title><![CDATA[Biotecnol Apl]]></abbrev-journal-title>
<issn>1027-2852</issn>
<publisher>
<publisher-name><![CDATA[Editorial Elfos Scientiae]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S1027-28522013000200008</article-id>
<title-group>
<article-title xml:lang="en"><![CDATA[A uniform digital identifier for scientific articles from manuscript through citation]]></article-title>
<article-title xml:lang="es"><![CDATA[Identificador digital uniforme para los artículos científicos desde el manuscrito hasta la citación]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Rodríguez]]></surname>
<given-names><![CDATA[Ernesto G]]></given-names>
</name>
<xref ref-type="aff" rid="A01"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Valdés]]></surname>
<given-names><![CDATA[Raúl A]]></given-names>
</name>
<xref ref-type="aff" rid="A01"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Ferrer]]></surname>
<given-names><![CDATA[Marta E]]></given-names>
</name>
<xref ref-type="aff" rid="A01"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Peña]]></surname>
<given-names><![CDATA[Dania A]]></given-names>
</name>
<xref ref-type="aff" rid="A01"/>
</contrib>
</contrib-group>
<aff id="A01">
<institution><![CDATA[,Centro de Ingeniería Genética y Biotecnología, CIGB Editorial Elfos Scientiae ]]></institution>
<addr-line><![CDATA[La Habana ]]></addr-line>
<country>Cuba</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>06</month>
<year>2013</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>06</month>
<year>2013</year>
</pub-date>
<volume>30</volume>
<numero>2</numero>
<fpage>142</fpage>
<lpage>144</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://scielo.sld.cu/scielo.php?script=sci_arttext&amp;pid=S1027-28522013000200008&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.sld.cu/scielo.php?script=sci_abstract&amp;pid=S1027-28522013000200008&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.sld.cu/scielo.php?script=sci_pdf&amp;pid=S1027-28522013000200008&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="en"><p><![CDATA[A uniform digital identifier (UDI) is presented for scientific manuscripts from editorial receipt through bibliographic citation. The UDI replaces conventional pagination and allows citing the manuscript upon acceptance, remaining as article's metadata after the assignation of bibliographic information (year, volume and issue). It provides explicit information on the journal, type of article, manuscript editorial ID code, acceptance date, and, if peer-reviewed (i.e., original research) the period in months of that process. Additionally, the language of publication can be added as ISO 639-1. Significantly, it provides uniform tracking of manuscripts from submission, functioning as locator for all the article versions, and increases the explicit information on editorial processing provided when citing the article in bibliographic references. The last one will favor the bibliometric analysis of editorial peer-review directly from reference lists, adding value to them and also to bibliographic database metadata.]]></p></abstract>
<abstract abstract-type="short" xml:lang="es"><p><![CDATA[Se propone un identificador digital uniforme (IDU) para manuscritos científicos desde la recepción editorial hasta la citación bibliográfica. El UDI reemplaza la paginación tradicional y permite citar el manuscrito tras su aceptación, y permanece como metadato del artículo después de asignarle a este la información bibliográfica (año, volumen y número). Este identificador proporciona información explícita sobre la revista, el tipo de artículo, el código de identificación de procesamiento editorial, la fecha de aceptación y, en caso de que el artículo sea evaluado por pares, el periodo de revisión en meses. Adicionalmente, se puede indicar el idioma del artículo mediante el código ISO 639-1. De forma significativa, el UDI permite el seguimiento uniforme del los artículos durante todo su ciclo de vida desde el envío, funciona como localizador de todas sus versiones e incrementa la información explícita sobre el procesamiento editorial, disponible como metadato al citarlo dentro de listas de referencias bibliográficas. Este último aspecto favorecería el análisis bibliométrico de los periodos de revisión por pares editorial a partir de las listas de referencias, y les añadiría valor a estas y a sus metadatos depositados en las bases de datos bibliográficas.]]></p></abstract>
<kwd-group>
<kwd lng="en"><![CDATA[persistent identifier]]></kwd>
<kwd lng="en"><![CDATA[uniform digital identifier]]></kwd>
<kwd lng="en"><![CDATA[journal article]]></kwd>
<kwd lng="en"><![CDATA[electronic publication]]></kwd>
<kwd lng="en"><![CDATA[scientific and technical publications]]></kwd>
<kwd lng="es"><![CDATA[identificador persistente]]></kwd>
<kwd lng="es"><![CDATA[identificador digital uniforme]]></kwd>
<kwd lng="es"><![CDATA[artículo de revista]]></kwd>
<kwd lng="es"><![CDATA[publicación electrónica]]></kwd>
<kwd lng="es"><![CDATA[publicaciones científicas y técnicas]]></kwd>
</kwd-group>
</article-meta>
</front><body><![CDATA[ <DIV class="Sect"   >        <P   align="right" ><font size="2" color="#000000" face="Verdana, Arial, Helvetica, sans-serif"><b>FOCUS</b>      </font></P >   <FONT size="+1" color="#000000">        <P   > </P >       <P   >&nbsp;</P >       <P   ><font size="2" face="Verdana, Arial, Helvetica, sans-serif"><b><font size="4">A      uniform digital identifier for scientific articles from manuscript through      citation </font></b></font></P >       <P   >&nbsp;</P >       <P   ></P >       <P   > </P >       <P   ><b><font size="3" face="Verdana, Arial, Helvetica, sans-serif">Identificador      digital uniforme para los art&iacute;culos cient&iacute;ficos desde el manuscrito      hasta la citaci&oacute;n </font></b></P >       <P   > </P >       ]]></body>
<body><![CDATA[<P   > </P >       <P   >&nbsp;</P >       <P   >&nbsp;</P >       <P   ><font size="2" face="Verdana, Arial, Helvetica, sans-serif"><b>Ernesto G Rodr&iacute;guez,      Ra&uacute;l A Vald&eacute;s, Marta E Ferrer, Dania A Pe&ntilde;a </b></font></P >       <P   ><font size="2" face="Verdana, Arial, Helvetica, sans-serif">Editorial Elfos Scientiae,      Centro de Ingenier&iacute;a Gen&eacute;tica y Biotecnolog&iacute;a, CIGB.      Ave. 31 e/ 158 y 190, Cubanac&aacute;n, Playa, CP 11 600, La Habana, Cuba.      </font></P >       <P   >&nbsp;</P >       <P   >&nbsp;</P >   </font>   <hr>   <FONT size="+1" color="#000000"> <b><font size="2" face="Verdana, Arial, Helvetica, sans-serif">ABSTRACT    </font></b>        <P align="left"   ><font size="2" face="Verdana, Arial, Helvetica, sans-serif">A uniform digital      identifier (UDI) is presented for scientific manuscripts from editorial receipt      through bibliographic citation. The UDI replaces conventional pagination and      allows citing the manuscript upon acceptance, remaining as article&rsquo;s      metadata after the assignation of bibliographic information (year, volume      and issue). It provides explicit information on the journal, type of article,      manuscript editorial ID code, acceptance date, and, if peer-reviewed (i.e.,      original research) the period in months of that process. Additionally, the      language of publication can be added as ISO 639-1. Significantly, it provides      uniform tracking of manuscripts from submission, functioning as locator for      all the article versions, and increases the explicit information on editorial      processing provided when citing the article in bibliographic references. The      last one will favor the bibliometric analysis of editorial peer-review directly      from reference lists, adding value to them and also to bibliographic database      metadata. </font></P >       <P   ><font size="2" face="Verdana, Arial, Helvetica, sans-serif"><b>Keywords:</b>      persistent identifier, uniform digital identifier, journal article, electronic      publication, scientific and technical publications. </font></P >   </font>    <hr>   <FONT size="+1" color="#000000">       <P   > </P >       ]]></body>
<body><![CDATA[<P   ><b><font size="2" face="Verdana, Arial, Helvetica, sans-serif">RESUMEN </font></b></P >       <P   ><font size="2" face="Verdana, Arial, Helvetica, sans-serif">Se propone un identificador      digital uniforme (IDU) para manuscritos cient&iacute;ficos desde la recepci&oacute;n      editorial hasta la citaci&oacute;n bibliogr&aacute;fica. El UDI reemplaza      la paginaci&oacute;n tradicional y permite citar el manuscrito tras su aceptaci&oacute;n,      y permanece como metadato del art&iacute;culo despu&eacute;s de asignarle      a este la informaci&oacute;n bibliogr&aacute;fica (a&ntilde;o, volumen y n&uacute;mero).      Este identificador proporciona informaci&oacute;n expl&iacute;cita sobre la      revista, el tipo de art&iacute;culo, el c&oacute;digo de identificaci&oacute;n      de procesamiento editorial, la fecha de aceptaci&oacute;n y, en caso de que      el art&iacute;culo sea evaluado por pares, el periodo de revisi&oacute;n en      meses. Adicionalmente, se puede indicar el idioma del art&iacute;culo mediante      el c&oacute;digo ISO 639-1. De forma significativa, el UDI permite el seguimiento      uniforme del los art&iacute;culos durante todo su ciclo de vida desde el env&iacute;o,      funciona como localizador de todas sus versiones e incrementa la informaci&oacute;n      expl&iacute;cita sobre el procesamiento editorial, disponible como metadato      al citarlo dentro de listas de referencias bibliogr&aacute;ficas. Este &uacute;ltimo      aspecto favorecer&iacute;a el an&aacute;lisis bibliom&eacute;trico de los      periodos de revisi&oacute;n por pares editorial a partir de las listas de      referencias, y les a&ntilde;adir&iacute;a valor a estas y a sus metadatos      depositados en las bases de datos bibliogr&aacute;ficas. </font></P >       <P   ><font size="2" face="Verdana, Arial, Helvetica, sans-serif"><b>Palabras clave:</b>      identificador persistente, identificador digital uniforme, art&iacute;culo      de revista, publicaci&oacute;n electr&oacute;nica, publicaciones cient&iacute;ficas      y t&eacute;cnicas. </font></P >   </font>    <hr>   <FONT size="+1" color="#000000">        <P   > </P >       <P   >&nbsp;</P >       <P   >&nbsp;</P >       <P   ><font size="2" face="Verdana, Arial, Helvetica, sans-serif"><B><font size="3">INTRODUCTION      </font></b></font></P >       <P   ><font size="2" face="Verdana, Arial, Helvetica, sans-serif">The generation of      information persistent identifiers (PIs) has characterized the last 20 years      of scientific literature and information sciences. Among the most widely known      and established variants are the uniform resource identifier (URI) [1], the      digital object identifier (DOI) [2, 3], the publisher item identifier (pii)      [4] and more recently the application identifiers (AIs) [5]. The first two      are intended for locating digitally the manuscript or the article, the pii      for tracking the manuscript during the editorial process and AIs to interconnect      physical objects with business related information. In the case of URI, DOI      and pii, all of them are based on previous PIs as the international standard      serial number (ISSN)[6] for periodicals or the international serial book number      (ISBN) [7]. </font></P >       <P   ><font size="2" face="Verdana, Arial, Helvetica, sans-serif">PIs have not been      limited to locate electronic contents, but has also expanded to other types      of identifiers for uniform tagging of scientific article metadata as the author      ID for authority control [8] (e.g., ResearcherID [9], and more recently, the      Scopus Sciverse&rsquo;s ORCID [10]) and articles version identifiers as CrossMark      [11]. </font></P >       <P   ><font size="2" face="Verdana, Arial, Helvetica, sans-serif">PIs aimed at identifying      scientific manuscripts irrupted in bibliographic guidelines and speedup scientific      articles consultation and citation as e-prints upon editorial acceptance.      However, bibliographic guidelines have derived in a myriad of citation variants      which are optional and the citation format generally differs for the same      article based on journals&rsquo; instructions for authors and bibliographic      style guidelines. This required the availability of tracking systems for article&rsquo;s      versions. At the same time, some of these identifiers require payment to be      assigned (DOI), and others (pii) are restrained to a publishing consortium.      For a more complicated picture, many journals have incorporated, rather than      migrated to, digital publishing, with authors mostly favoring citation of      the printed version of the article as the most traditional one. This has led      strictly electronic journals to use unique codes for the articles instead      of pagination (e.g., PLoS journals [12]) and exclusively to identify the article      during the editorial process (the case of pii), all of them coexisting at      a given time. </font></P >       ]]></body>
<body><![CDATA[<P   align="justify" ><font size="2" face="Verdana, Arial, Helvetica, sans-serif">Simultaneously, bibliographic      formats have evolved to use those identifiers for citation. For example, in      the Vancouver citation style [13], a standard journal citation provides: i)      author names, limited to six; ii) article title; iii) journal name; iv) publishing      date (year), sometimes the electronic immediate publishing date which is optional;      and v) archivistic metadata (volume, issue and pagination). All these characterize      the act of publishing and indicate the location of the article within a journal      collection. Nevertheless, pagination has lost its original aim to some extent      in strictly electronic journals, since the order of a given resource within      a digital collection is determined by location rather by sequence, and is      searched selectively rather than sequentially. Furthermore, unless consulting      the journal table of contents, the most probable way to find the article would      be metadata-based retrieval or through journal website searches. </font></P >   <FONT size="+1">        <P   align="justify" ><font size="2" face="Verdana, Arial, Helvetica, sans-serif">Noteworthy, PIs for      scientific articles aid on tracking them at the preprint stage, but lack explicit      information on the source, even when used as locator (DOI). This brings a      space to optimize the information expected or useful for researchers and editorial      boards when consulting the reference lists of articles, to make them more      meaningful. </font></P >       <P   align="justify" ><font size="2" face="Verdana, Arial, Helvetica, sans-serif">In order to satisfy      all the abovementioned requirements, a new system for bibliographic citation      of scientific articles, denominated uniform digital identifier (UDI) is stated      here. </font></P >       <P   align="justify" >&nbsp;</P >       <P   ><font size="2" face="Verdana, Arial, Helvetica, sans-serif"><B><font size="3">RESULTS      AND DISCUSSION </font> </b></font></P >   <FONT size="+1">        <P   align="justify" ><font size="2" face="Verdana, Arial, Helvetica, sans-serif">After analyzing all      the alternatives, and upon study of bibliographic style guidelines, a new      system was proposed which unifies all the points of views on editorial processing      information, that provided to readers on the nature of citation and aid on      locating the articles. The structure of the identifier was established taking      into account the general properties of manuscripts processed and published      in the <I>Biotecnolog&iacute;a Aplicada</I> journal, and further challenged      with the bibliographic requirements of the Vancouver style guidelines. </font></P >   <FONT size="+1">        <P   align="justify" ><font size="2" face="Verdana, Arial, Helvetica, sans-serif">The uniform digital      identifier (UDI) structure is shown in the <a href="#fig1">figure</a>. It      comprises from left to right: the initials identifying journal name, a letter      indicating the journal&rsquo;s section, the sequential manuscript ID number,      acceptance date (for peer-reviewed articles, or the receipt date for the non-peer-reviewed      ones), two digits for the extent in month of the peer-review process, and      finally, the two letter 639-1 ISO code for language identification [14]. </font></P >       <P   align="center" ><img src="/img/revistas/bta/v30n2/f0108213.gif" width="387" height="434"><a name="fig1"></a></P >       
<P   align="justify" ><font size="2" face="Verdana, Arial, Helvetica, sans-serif">The journal section      letter and the sequential manuscript ID number supports tracking the manuscript      from receipt to citation, unifying the life cycle of the article, a connection      traditionally lost after publishing. The sequential number was set to three      digits, regarding that submissions would never exceed 999 manuscripts for      a given journal per month. The two-digit standard acceptance date (month and      year) coincides with the publication date in the case of strictly electronic      journals, and eliminates citation mistakes due to different acceptance and      publication years. Traditionally, these data remain internal in the manuscript      and are troublesome to retrieve, depending on consultation for bibliometric      analyses. In this way, the meaning of reference lists is expanded for bibliometrics,      and supports the related editorial processing times becoming metadata. Moreover,      it is also possible to calculate corrected Price indexes. </font></P >       <P   align="justify" ><font size="2" face="Verdana, Arial, Helvetica, sans-serif">The inclusion of      the peer-review period in months brings two parameters: i) the extension of      peer-review, required for editorial processing calculations; ii) the character      of the article (reviewed or not, in this last case, 00) and, therefore, if      citable; and also supports calculating submission date. </font></P >       ]]></body>
<body><![CDATA[<P   align="justify" ><font size="2" face="Verdana, Arial, Helvetica, sans-serif">The UDI was structured      modular to indicate the original character of the article on its present form,      directly from the list of references, in which will reinforce the dominance      of bibliographic databases and allow automated statistics. Moreover, it aids      on the assignation of authorship by cross-field match of author names to articles&rsquo;      metadata, helping on authority control. It can also be created for existing      journal collections, cost-free. </font></P >       <P   align="justify" ><font size="2" face="Verdana, Arial, Helvetica, sans-serif">Once established,      the UDI was challenged with the Vancouver bibliographic style. It is consistent      with the coexistence of both article&acute;s versions: accepted and published;      in the last, it is compatible with the full bibliographic format. For this,      the traditional print pagination was replaced by the UDI. In case of printed      editions, the page number can be indicated in the table of contents or even      added as a modular number. </font></P >       <P   align="justify" ><font size="2" face="Verdana, Arial, Helvetica, sans-serif">Example citations      are: </font></P >       <P   ><font size="2" face="Verdana, Arial, Helvetica, sans-serif"><I>Accepted preprint      </I></font></P >       <P   align="justify" ><font size="2" face="Verdana, Arial, Helvetica, sans-serif">Rodr&iacute;guez      EG, Vald&eacute;s RA, Ferrer ME, Pe&ntilde;a DA. A uniform digital identifier      for scientific articles from manuscript through citation. Biotechnol Apl.      BAF339-041300EN. </font></P >       <P   ><font size="2" face="Verdana, Arial, Helvetica, sans-serif"><I>Bibliographic      citation </I></font></P >       <P   align="justify" ><font size="2" face="Verdana, Arial, Helvetica, sans-serif">Rodr&iacute;guez      EG, Vald&eacute;s RA, Ferrer ME, Pe&ntilde;a DA. A uniform digital identifier      for scientific articles from manuscript through citation. Biotechnol Apl.      2013; 30(2):BAF339-041300EN. </font></P >       <P   align="justify" > </P >       <P   align="justify" ><font size="2" face="Verdana, Arial, Helvetica, sans-serif">This format provides      all the three relevant publication dates from the single citation act: submission,      online publishing and archivistic recording (bibliographic data). The code      provides a probability of 9038952 non-overlapping combinations, including      time related parameters, as calculated for <I>Biotecnolog&iacute;a Aplicada</I>      (8 article types/sections &times; 999 sequential ID submission codes per month      top &times; 87 years left from the 21rst century &times; 13 values available      for peer-review period including 12 months and also the 00 value for non-reviewed      articles or under open peer-review if unpublished). The peer-review period      can exceed 12 months, regardless first submission or not. In the case of resubmission,      it can be indicated by an additional R letter prior to the acceptance date,      which can also provide information on iterative peer-review, something missing      in bibliographic citation styles enforced. </font></P >       <P   align="justify" ><font size="2" face="Verdana, Arial, Helvetica, sans-serif">The UDI may also      avoid metadata dispersion, something that is not completely eliminated with      the optional use of pii and DOI when they replace the entire bibliographic      information, and at the same time, the article can be tracked easily by open      or database-directed bibliographic searches. Very significantly, it provides      information on the article&acute;s editorial processing at those two publication      stages, which can be visually inspected and also automatically harvested.      Moreover, it solves the limitations of current bibliographic formats on lacking      data about the citation character of the document source, which is not indicated      uniformly in the title (for example, for letters and editorials within brackets).      In this sense, the UDI is highly valuable by indicating not only the citation      character of the references, but also supporting its classification in primary      or secondary sources of information within the lists of references, relevant      for establishing the intellectual base of the article considered. The lack      of all the information included in the UDI as part of reference lists has      limited a unified study of scientific literature and the integrative characterization      of bibliometric trends since the intellectual background perspective. For      article types, a more homogeneous convention could be established by limiting      R for reviews and O for original research articles, respectively (<a href="#fig1">Figure</a>),      the other article type one-letter definitions being more flexible based on      the journal sections. </font></P >       ]]></body>
<body><![CDATA[<P   align="justify" ><font size="2" face="Verdana, Arial, Helvetica, sans-serif">Additionally, the      UDI does not discard any previous bibliographic element, integrating all of      them, and, at the same time, allows version location for the article since      it is assigned by the journal. It also unifies the multi-language character      of publications as <I>Biotecnolog&iacute;a Aplicada</I>, for articles simultaneously      published in two or more languages, but retaining the single article identity.      </font></P >       <P   align="justify" ><font size="2" face="Verdana, Arial, Helvetica, sans-serif">In summary, the future      practice on using UDI would mark a valuable contribution to information sciences,      by unifying the whole submission-publishing-citation life cycle of scientific      articles. </font></P >       <P   align="justify" >&nbsp;</P >       <P   > </P >   <FONT size="+1">        <P   ><font size="3"><b><font face="Verdana, Arial, Helvetica, sans-serif">REFERENCES      </font></b></font></P >       <!-- ref --><P   align="justify" ><font size="2" face="Verdana, Arial, Helvetica, sans-serif">1. Green B, Bide      M. Unique Identifiers: a brief introduction. London: Book Industry Communication      ; 1999. Available from: <FONT color="#0000FF"><a href="http://www.bic.org.uk/files/pdfs/uniquid.pdf" target="_blank">http://www.bic.org.uk/files/pdfs/uniquid.pdf</a><FONT color="#000000">.          </font></font></font></P >   <FONT size="+1"><FONT size="+1"><FONT size="+1"><FONT color="#0000FF"><FONT color="#000000">        <P   align="justify" ><font size="2" face="Verdana, Arial, Helvetica, sans-serif">2. International      DOI Foundation. The DOI&reg; system. Available from: <A href="http://www.doi.org/" target="_blank">      <FONT color="#0000FF">www.doi.org</font></A><FONT color="#0000FF"><FONT color="#000000">.      </font></font></font></P >   <FONT color="#0000FF"><FONT color="#000000"><FONT color="#0000FF">        <P   align="justify" ><font color="#000000" size="2" face="Verdana, Arial, Helvetica, sans-serif">3.      Paskin N. Digital Object Identifier (DOI&reg;) System. In: Bates MJ, Maack      MN, editors. Encyclopedia of Library and Information Sciences. 3rd ed. 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Available from: <FONT color="#0000FF"><a href="http://www.gs1.org/barcodes/technical/application_identifiers" target="_blank">http://www.gs1.org/barcodes/technical/application_identifiers</a>.          </font></font></P >   <FONT color="#0000FF"><FONT color="#000000">        <P   align="justify" ><font size="2" face="Verdana, Arial, Helvetica, sans-serif">6. What is an ISSN?      Paris: Centre International de l&rsquo;ISSN. c2008 [cited 2013 May 3]. ISSN      International Centre; [1 screen]. Available from: <A href="http://www.issn.org/2-22635-What-is-an-ISSN.php" target="_blank">      <FONT color="#0000FF">http://www.issn.org/2-22635-What-is-an-ISSN.php</font></A><FONT color="#0000FF"><FONT color="#000000">.      </font></font></font></P >   <FONT size="+1"><FONT size="+1"><FONT color="#0000FF"><FONT color="#000000">        <!-- ref --><P   align="justify" ><font size="2" face="Verdana, Arial, Helvetica, sans-serif">7. International      ISBN Agency [Internet]. 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<body><![CDATA[<P   align="justify" >&nbsp;</P >       <P   align="justify" >&nbsp;</P >   <FONT color="#0000FF">        <P   align="justify" > </P >       <P   align="justify" ><i><font color="#000000" size="2" face="Verdana, Arial, Helvetica, sans-serif">Ernesto      G Rodr&iacute;guez</font></i><font color="#000000" size="2" face="Verdana, Arial, Helvetica, sans-serif">.      Editorial Elfos Scientiae, Centro de Ingenier&iacute;a Gen&eacute;tica y Biotecnolog&iacute;a,      CIGB. Ave. 31 e/ 158 y 190, Cubanac&aacute;n, Playa, CP 11 600, La Habana,      Cuba. E-mail: <A href="mailto:ernesto.galban@cigb.edu.cu"> <FONT color="#0000FF">ernesto.galban@cigb.edu.cu</font></A><FONT color="#0000FF">.      </font></font></P >   </font></font></font></font></font></font></font></font></font></font></font></font></font></font></font></font></font></font></font></font></font></font></font></font></font></font></font></font></font></font></font></DIV >      ]]></body><back>
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