<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>1561-3194</journal-id>
<journal-title><![CDATA[Revista de Ciencias Médicas de Pinar del Río]]></journal-title>
<abbrev-journal-title><![CDATA[Rev Ciencias Médicas]]></abbrev-journal-title>
<issn>1561-3194</issn>
<publisher>
<publisher-name><![CDATA[Editorial Ciencias Médicas]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S1561-31942022000300004</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Evolución de defectos óseos periodontales tratados con plasma rico en plaquetas]]></article-title>
<article-title xml:lang="en"><![CDATA[Evolution of periodontal defects bone treated with platelets rich-plasm]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Peña-Sisto]]></surname>
<given-names><![CDATA[Maritza]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Universidad de Ciencias Médicas de Santiago de Cuba Hospital Clínico Quirúrgico Juan Bruno Zayas Alfonso ]]></institution>
<addr-line><![CDATA[Santiago de Cuba ]]></addr-line>
<country>Cuba</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>06</month>
<year>2022</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>06</month>
<year>2022</year>
</pub-date>
<volume>26</volume>
<numero>3</numero>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://scielo.sld.cu/scielo.php?script=sci_arttext&amp;pid=S1561-31942022000300004&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.sld.cu/scielo.php?script=sci_abstract&amp;pid=S1561-31942022000300004&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.sld.cu/scielo.php?script=sci_pdf&amp;pid=S1561-31942022000300004&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[RESUMEN  Introducción:  los factores bioactivos y entre ellos, los concentrados plaquetarios, son empleados como terapia para la reparación y cicatrización de los tejidos periodontales por su potencial regenerativo.  Objetivo:  evaluar la evolución de defectos óseos periodontales tratados con plasma rico en plaquetas, en pacientes con periodontitis, en Santiago de Cuba, en el período 2017-2019.  Método:  se realizó un estudio longitudinal prospectivo en Santiago de Cuba, desde diciembre del 2017 hasta diciembre del 2019, en pacientes de ambos sexos, entre 30 y 59 años de edad, con diagnóstico de periodontitis que requerían tratamiento quirúrgico, seleccionándose una muestra de 45 pacientes que presentaban al menos un sitio con defectos intraóseos periodontales, de 4 o más milímetros de profundidad, que cumplían con el diagnóstico y los criterios para utilizar Plasma Rico en Plaquetas. Se utilizaron variables clínicas, radiográficas y de respuesta, expresadas en frecuencias absolutas/relativas y media aritmética, con desviación estándar y validación con la prueba t.  Resultados:  el 93,3 % de los casos lograron signos clínicos de normalidad del tejido blando intervenido a los 7 días. El sangrado al sondaje, a los seis meses de evolución, solo persistió en el 4,4 % de los casos. La comparación de medias de movilidad dentaria, profundidad al sondaje y pérdida de inserción clínica antes y después del tratamiento, disminuyeron significativamente.  Conclusiones:  la evolución de los parámetros periodontales evaluados en los defectos óseos, tras la aplicación de plasma rico en plaquetas, como parte del tratamiento quirúrgico en las periodontitis, fue satisfactoria en casi la totalidad de los casos, con mejoría clínica.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[ABSTRACT  Introduction: bioactive factors, including platelet concentrates, are used as therapy for the repair and healing of periodontal tissues due to their regenerative potential.  Objective: to evaluate the evolution of periodontal bone defects treated with platelet-rich plasma, in patients with periodontitis, in Santiago de Cuba, during the period 2017-2019.  Methods: a prospective longitudinal study was conducted in Santiago de Cuba, from December 2017 to December 2019, in patients of both sexes, between 30 and 59 years old, with a diagnosis of periodontitis requiring surgical treatment, choosing a sample of 45 patients presenting at least one site with periodontal intra-osseous defects, 4 or more millimeters deep, who met the diagnosis and criteria for using Platelet-Rich Plasma. Clinical, radiographic and response variables were used, expressed in absolute/relative frequencies and arithmetic mean, with standard deviation and t-test validation.  Results: the 93,3 % of the cases achieved clinical signs of normality of the operated soft tissue at 7 days. Bleeding on probing at six months of evolution persisted in only 4,4 % of the cases. The comparison of mean tooth mobility, probing depth and clinical insertion loss before and after treatment decreased significantly.  Conclusions: the evolution of periodontal parameters evaluated in bone defects after the application of platelet-rich plasma as part of the surgical treatment of periodontitis was satisfactory in almost the totality of the patients, with clinical improvement.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[PERIODONCIA]]></kwd>
<kwd lng="es"><![CDATA[PLASMA RICO EN PLAQUETAS]]></kwd>
<kwd lng="es"><![CDATA[REGENERACIÓN ÓSEA]]></kwd>
<kwd lng="es"><![CDATA[MEDICINA REGENERATIVA]]></kwd>
<kwd lng="en"><![CDATA[PERIODONTICS]]></kwd>
<kwd lng="en"><![CDATA[PLATELET-RICH PLASMA]]></kwd>
<kwd lng="en"><![CDATA[BONE REGENERATION]]></kwd>
<kwd lng="en"><![CDATA[REGENERATIVE MEDICINE]]></kwd>
</kwd-group>
</article-meta>
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<ref id="B20">
<label>20</label><nlm-citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname><![CDATA[Cruz]]></surname>
<given-names><![CDATA[MC]]></given-names>
</name>
<name>
<surname><![CDATA[Castro]]></surname>
<given-names><![CDATA[RY]]></given-names>
</name>
</person-group>
<article-title xml:lang=""><![CDATA[Resultados de los concentrados plaquetarios en la regeneración ósea guiada]]></article-title>
<source><![CDATA[Rev Cubana Invest Bioméd]]></source>
<year>2020</year>
<volume>39</volume>
<numero>2</numero>
<issue>2</issue>
</nlm-citation>
</ref>
</ref-list>
</back>
</article>
