1727-8120 1727-8120 S1727-81202023000200001 Cuba Cuba Cuba 00 08 2023 00 08 2023 23 2

1 2006 2 2017 21 3 3 3 2018 4 2018 13 42 42 5 2019 6 2012 31 1 1 7 2019 15 3 3 8 Declaration of Helsinki 2013 310 20 20 9 2014 20 ^s1 ^s1 1 10 2020 24 1 1 11 2020 12 2020 39 1 1 13 2021 35 1 1 14 2020 37 1 1 15 2022 22 02 02 16 2019 58 271 271 17 2015 19 5 5 18 2018 21 5 5