<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>2078-7170</journal-id>
<journal-title><![CDATA[CorSalud]]></journal-title>
<abbrev-journal-title><![CDATA[CorSalud]]></abbrev-journal-title>
<issn>2078-7170</issn>
<publisher>
<publisher-name><![CDATA[Cardiocentro Ernesto Che Guevara]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S2078-71702019000200146</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Repolarización ventricular en la terapia oncológica]]></article-title>
<article-title xml:lang="en"><![CDATA[Ventricular repolarization in cancer therapy]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Dorantes Sánchez]]></surname>
<given-names><![CDATA[Margarita]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Bazán Milián]]></surname>
<given-names><![CDATA[Manuel]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Instituto de Cardiología y Cirugía Cardiovascular Servicio de Arritmias y Estimulación Cardíaca ]]></institution>
<addr-line><![CDATA[La Habana ]]></addr-line>
<country>Cuba</country>
</aff>
<aff id="Af2">
<institution><![CDATA[,Instituto Nacional de Oncología y Radiobiología Departamento de Cardiología ]]></institution>
<addr-line><![CDATA[La Habana ]]></addr-line>
<country>Cuba</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>06</month>
<year>2019</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>06</month>
<year>2019</year>
</pub-date>
<volume>11</volume>
<numero>2</numero>
<fpage>146</fpage>
<lpage>152</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://scielo.sld.cu/scielo.php?script=sci_arttext&amp;pid=S2078-71702019000200146&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.sld.cu/scielo.php?script=sci_abstract&amp;pid=S2078-71702019000200146&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.sld.cu/scielo.php?script=sci_pdf&amp;pid=S2078-71702019000200146&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[RESUMEN Se discuten los procesos de despolarización y repolarización ventriculares, con su falta de uniformidad y su heterogeneidad, tanto en pacientes con corazón sano como en aquellos enfermos, cuestión de rangos. Se analizan las mediciones que expresan las características de la repolarización ventricular: el intervalo QT y otras mediciones incluso más fidedignas como el intervalo TPICO-TFINAL, su dispersión y otras. Se precisa la existencia del signo y del síndrome de QT largo, así como los tres procesos básicos de la arritmogenia: la heterogeneidad, la alternancia y la dispersión, con las diferencias de los potenciales de acción en las tres zonas del miocardio ventricular. Se precisan los factores de riesgo del QT largo (común con esta terapia), de las arritmias ventriculares (en especial la torsión de puntas, extremadamente rara en estos casos) y se discute la necesidad de valorar datos clínicos, eléctricos, comorbilidades, conflictos agregados y las medidas a tomar en estos pacientes.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[ABSTRACT Ventricular depolarization and repolarization processes are discussed, including their differences and heterogeneity both in patients with a healthy/sick heart, a matter of ranges. Measurements expressing the characteristics of ventricular repolarization are analyzed: the QT interval and other even more reliable measurements such as the TPEAK-TEND interval, its dispersion and others. We emphasize on the existence of the long QT syndrome (and sign) and the three basic processes of arrhythmogenesis: heterogeneity, alternation and dispersion, with differences in action potentials in the three zones of the ventricular myocardium. The risk factors of long QT (common in this therapy) and ventricular arrhythmias (especially torsades de pointes, extremely rare in these cases) are highlighted. The need to assess clinical and electrical features, comorbidities, aggregate conflicts, and management of these patients is also discussed.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[Repolarización ventricular]]></kwd>
<kwd lng="es"><![CDATA[Terapia oncológica]]></kwd>
<kwd lng="es"><![CDATA[Antineoplásicos]]></kwd>
<kwd lng="es"><![CDATA[Arritmias cardíacas]]></kwd>
<kwd lng="es"><![CDATA[Intervalo QT]]></kwd>
<kwd lng="en"><![CDATA[Ventricular repolarization]]></kwd>
<kwd lng="en"><![CDATA[Cancer therapy]]></kwd>
<kwd lng="en"><![CDATA[Antineoplastic agents]]></kwd>
<kwd lng="en"><![CDATA[Cardiac arrhythmias]]></kwd>
<kwd lng="en"><![CDATA[QT interval]]></kwd>
</kwd-group>
</article-meta>
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