<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>2709-7927</journal-id>
<journal-title><![CDATA[Acta Médica del Centro]]></journal-title>
<abbrev-journal-title><![CDATA[Acta méd centro]]></abbrev-journal-title>
<issn>2709-7927</issn>
<publisher>
<publisher-name><![CDATA[Hospital Provincial Clínico Quirúrgico Universitario Arnaldo Milián Castro]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S2709-79272021000100072</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Agrandamiento gingival medicamentoso en pacientes que padecen hipertensión, cardiopatías y epilepsia]]></article-title>
<article-title xml:lang="en"><![CDATA[Medicated gingival enlargement in patients suffering from hypertension, heart disease and epilepsy]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Montes de Oca González]]></surname>
<given-names><![CDATA[Ana Mary]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[González Falcón]]></surname>
<given-names><![CDATA[Marisol]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Veitia Cabarrocas]]></surname>
<given-names><![CDATA[Felisa]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Lahera Fernádez]]></surname>
<given-names><![CDATA[Ena Luisa]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Díaz López]]></surname>
<given-names><![CDATA[Odalis Beatriz]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Hernández González]]></surname>
<given-names><![CDATA[Ana Beatriz]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Universidad de Ciencias Médicas de Villa Clara  ]]></institution>
<addr-line><![CDATA[Santa Clara Villa Clara]]></addr-line>
<country>Cuba</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>03</month>
<year>2021</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>03</month>
<year>2021</year>
</pub-date>
<volume>15</volume>
<numero>1</numero>
<fpage>72</fpage>
<lpage>80</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://scielo.sld.cu/scielo.php?script=sci_arttext&amp;pid=S2709-79272021000100072&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.sld.cu/scielo.php?script=sci_abstract&amp;pid=S2709-79272021000100072&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.sld.cu/scielo.php?script=sci_pdf&amp;pid=S2709-79272021000100072&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[RESUMEN  Introducción:  el agrandamiento gingival medicamentoso es el efecto indeseado más extendido de la medicación sistémica sobre los tejidos periodontales, se implican con mayor frecuencia los medicamentos: fenitoína, ciclosporina y nifedipina, y no existe consenso respecto a las cifras exactas de prevalencia.  Objetivo:  caracterizar el agrandamiento gingival medicamentoso en pacientes que padecen hipertensión, cardiopatía y epilepsia del Consultorio del Médico de la Familia 21-8 del Policlínico &#8220;XX Aniversario&#8221;.  Método:  se realizó un estudio descriptivo observacional de corte transversal. Se seleccionaron los casos por muestreo no probabilístico intencional por criterios, la muestra quedó conformada por 46 personas. Se aplicaron métodos teóricos y empíricos que incluyeron la aplicación de índices epidemiológicos. La información se agrupó en tablas de contingencias y frecuencias.  Resultados:  la prevalencia de agrandamiento gingival fue de 4,3% sin distinción de edad ni sexo y afectó a los que padecen epilepsia. La fenitoína y la carbamazepina fueron los medicamentos que lo produjeron, se identificaron los factores de riesgo: edad, sexo, tiempo y dosis de consumo del fármaco, higiene bucal y estado periodontal.  Conclusiones:  la prevalencia de agrandamiento gingival fue baja, con severidad grado 2 y 3, exclusiva de pacientes epilépticos tratados con carbamazepina y fenitoína. Afectó por igual a jóvenes de ambos sexos. La higiene bucal deficiente y la enfermedad periodontal inflamatoria crónica estuvieron presentes.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[ABSTRACT  Introduction:  medicated gingival enlargement is the most widespread undesirable effect of systemic medication on periodontal tissues, the most frequently implicated drugs are phenytoin, cyclosporine and nifedipine, and there is no consensus on exact prevalence figures.  Objective:  to characterize medicinal gingival enlargement in patients suffering from hypertension, cardiopathy and epilepsy at the Family Physician's Office 21-8 of the &#8220;XX Aniversario&#8221; Polyclinic.  Method:  a cross-sectional, descriptive, observational study was conducted. Cases were selected by intentional non-probabilistic sampling by criteria, the sample was made up of 46 people. Theoretical and empirical methods were applied that included the application of epidemiological indices. The information was grouped in tables of contingencies and frequencies.  Results:  the prevalence of gingival enlargement was 4.3% without distinction of age or sex and it affected those who suffer from epilepsy. Phenytoin and carbamazepine were the drugs that produced it, risk factors were identified: age, sex, time and dose of drug consumption, oral hygiene and periodontal condition.  Conclusions:  prevalence of gingival enlargement was low, with severity grade 2 and 3, exclusive of epileptic patients treated with carbamazepine and phenytoin. It affected equally young people of both sexes. Poor oral hygiene and chronic inflammatory periodontal disease were present.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[enfermedades de las encías]]></kwd>
<kwd lng="es"><![CDATA[hiperplasia gingival]]></kwd>
<kwd lng="es"><![CDATA[agrandamiento gingival]]></kwd>
<kwd lng="es"><![CDATA[fármaco inducido]]></kwd>
<kwd lng="en"><![CDATA[gingival diseases]]></kwd>
<kwd lng="en"><![CDATA[gingival enlargement]]></kwd>
<kwd lng="en"><![CDATA[induced drug]]></kwd>
<kwd lng="en"><![CDATA[gingival hyperplasia]]></kwd>
</kwd-group>
</article-meta>
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