<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>0034-7507</journal-id>
<journal-title><![CDATA[Revista Cubana de Estomatología]]></journal-title>
<abbrev-journal-title><![CDATA[Rev Cubana Estomatol]]></abbrev-journal-title>
<issn>0034-7507</issn>
<publisher>
<publisher-name><![CDATA[Editorial Ciencias Médicas]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S0034-75072020000100002</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Calcificaciones pulpares en pacientes con diabetes mellitus]]></article-title>
<article-title xml:lang="en"><![CDATA[Pulp calcifications in patients with diabetes mellitus]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Araya]]></surname>
<given-names><![CDATA[Pilar]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Vega-Marcich]]></surname>
<given-names><![CDATA[Macarena]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Olivares]]></surname>
<given-names><![CDATA[Karla]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Wilhelm]]></surname>
<given-names><![CDATA[Carol]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Chaple Gil]]></surname>
<given-names><![CDATA[Alain Manuel]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Fernández]]></surname>
<given-names><![CDATA[Eduardo]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
<xref ref-type="aff" rid="Aaf"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Toro]]></surname>
<given-names><![CDATA[Mauricio]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
<xref ref-type="aff" rid="Aaf"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Universidad Andres Bello Facultad de Odontología ]]></institution>
<addr-line><![CDATA[Santiago de Chile ]]></addr-line>
<country>Chile</country>
</aff>
<aff id="Af2">
<institution><![CDATA[,Universidad de Ciencias Médicas de La Habana Facultad de Ciencias Médicas "Victoria de Girón" ]]></institution>
<addr-line><![CDATA[La Habana ]]></addr-line>
<country>Cuba</country>
</aff>
<aff id="Af3">
<institution><![CDATA[,Universidad Autónoma de Chile Instituto de Ciencias Biomédicas ]]></institution>
<addr-line><![CDATA[Santiago de Chile ]]></addr-line>
<country>Chile</country>
</aff>
<aff id="Af4">
<institution><![CDATA[,Universidad de Chile Facultad de Odontología Departamento de Odontología Restauradora]]></institution>
<addr-line><![CDATA[Santiago de Chile ]]></addr-line>
<country>Chile</country>
</aff>
<aff id="Af5">
<institution><![CDATA[,Universidad de Chile Facultad de Odontología Departamento de Prótesis Dental]]></institution>
<addr-line><![CDATA[Santiago de Chile ]]></addr-line>
<country>Chile</country>
</aff>
<aff id="Af6">
<institution><![CDATA[,Universidad Politécnica y Artística del Paraguay  ]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
<country>Paraguay</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>03</month>
<year>2020</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>03</month>
<year>2020</year>
</pub-date>
<volume>57</volume>
<numero>1</numero>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://scielo.sld.cu/scielo.php?script=sci_arttext&amp;pid=S0034-75072020000100002&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.sld.cu/scielo.php?script=sci_abstract&amp;pid=S0034-75072020000100002&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.sld.cu/scielo.php?script=sci_pdf&amp;pid=S0034-75072020000100002&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[RESUMEN  Introducción:  Las células de la pulpa dental tienen la capacidad, ante estímulos locales y sistémicos, de activar a la osteopontina, formando calcificaciones pulpares, bloqueando los conductos radiculares y modificando la anatomía interna; de manera que se intensifican en personas con diabetes mellitus.  Objetivo:  Determinar si existe mayor presencia de calcificaciones a nivel de cámara pulpar en pacientes con diabetes mellitus versus pacientes sin diabetes mellitus.  Métodos:  Se realizó un estudio de casos y controles, analítico, transversal y retrospectivo. Se utilizaron los registros clínicos y las radiografías digitales periapicales de pacientes de las clínicas odontológicas de pregrado (Prótesis, Restauradora, Integral, Periodoncia) y de postgrado (Periodoncia e Implantología quirúrgica) de la Universidad Andrés Bello - Chile, entre los años 2017 y 2018. Se seleccionó una muestra de 617 dientes (45 pacientes) luego de ser aplicados los criterios de exclusión e inclusión en la base de datos clínica. La muestra completó dos grupos, grupo de casos (22 pacientes): dientes de pacientes con diabetes mellitus 228 dientes indemnes y el grupo de control (23 pacientes): dientes de pacientes sin diabetes mellitus 389 dientes indemnes. Se realizó una calibración previa entre los investigadores para la identificación y clasificación de calcificaciones pulpares durante el análisis radiográfico de estas. Se realizaron inferencias estadísticas de chi cuadrado para establecer significación de los resultados obtenidos.  Resultados:  Los dientes de 22 pacientes diabéticos presentaron más calcificaciones camerales que los dientes de 23 pacientes no diabéticos, para 50 % de dientes calcificados en pacientes diabéticos (n=114) y 26 % en pacientes no diabéticos (n=101); este resultado fue estadísticamente significativo (pvalor&lt; 0,001).  Conclusiones:  Los pacientes con diabetes mellitus demostraron que son más propensos a formar calcificaciones camerales debido al aumento de glucosa presente en la sangre que activa a la osteopontina.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[ABSTRACT  Introduction:  Dental pulp cells have the capacity to respond to local and systemic stimuli by activating osteopontin, forming pulp calcifications, blocking root canals and modifying internal anatomy, in such a way that they intensify in people with diabetes mellitus.  Objective:  Determine whether there is a greater presence of calcifications in the pulp chamber of patients with diabetes mellitus vs. patients without diabetes mellitus.  Methods:  An analytical cross-sectional retrospective case-control study was conducted of medical records and digital periapical radiographs of patients attending undergraduate dental clinics (prosthesis, restoration, comprehensive, periodontics) and graduate dental clinics (periodontics and surgical implantology) of Andrés Bello University, Chile, in the period 2017-2018. A sample was selected of 617 teeth (45 patients) from the clinical database upon applying exclusion and inclusion criteria. The sample was divided into two groups: a case group, formed by 228 undamaged teeth from 22 patients with diabetes mellitus, and a control group, formed by 389 undamaged teeth from 23 patients without diabetes mellitus. Prior calibration was performed by the researchers to identify and classify the pulp calcifications during their radiographic analysis. Chi-squared statistical inferences were made to establish the significance of the results obtained.  Results:  The teeth from the 22 diabetic patients had more chamber calcifications than the teeth from the 23 nondiabetic patients, for 50% calcified teeth in diabetic patients (n= 114) and 26% in nondiabetic patients (n= 101). This result was statistically significant (p-value&lt; 0.001).  Conclusions:  Patients with diabetes mellitus were found to be more prone to form chamber calcifications, due to the increase in glucose present in the blood which activates osteopontin.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[calcificaciones de la pulpa dental]]></kwd>
<kwd lng="es"><![CDATA[calcificación de dientes]]></kwd>
<kwd lng="es"><![CDATA[diabetes mellitus]]></kwd>
<kwd lng="en"><![CDATA[dental pulp calcifications]]></kwd>
<kwd lng="en"><![CDATA[tooth calcification]]></kwd>
<kwd lng="en"><![CDATA[diabetes mellitus]]></kwd>
</kwd-group>
</article-meta>
</front><back>
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