<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>0034-7507</journal-id>
<journal-title><![CDATA[Revista Cubana de Estomatología]]></journal-title>
<abbrev-journal-title><![CDATA[Rev Cubana Estomatol]]></abbrev-journal-title>
<issn>0034-7507</issn>
<publisher>
<publisher-name><![CDATA[Editorial Ciencias Médicas]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S0034-75072022000300006</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Terapia probiótica multicepa como coadyuvante al tratamiento periodontal convencional]]></article-title>
<article-title xml:lang="en"><![CDATA[Multi-strain probiotic therapy as an adjuvant to conventional periodontal treatment]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Quintero Rojas]]></surname>
<given-names><![CDATA[Jormany]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Varela Rangel]]></surname>
<given-names><![CDATA[Yasmin Yinec]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Gutiérrez Flores]]></surname>
<given-names><![CDATA[Rodolfo]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Salas Osorio]]></surname>
<given-names><![CDATA[Elaysa]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Universidad de Los Andes Facultad de Odontología Departamento de Biopatología, Cátedra de Microbiología]]></institution>
<addr-line><![CDATA[Mérida ]]></addr-line>
<country>Venezuela</country>
</aff>
<aff id="Af2">
<institution><![CDATA[,Universidad de Los Andes Facultad de Odontología Departamento de Medicina Oral, Cátedra de Periodoncia]]></institution>
<addr-line><![CDATA[Mérida ]]></addr-line>
<country>Venezuela</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>09</month>
<year>2022</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>09</month>
<year>2022</year>
</pub-date>
<volume>59</volume>
<numero>3</numero>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://scielo.sld.cu/scielo.php?script=sci_arttext&amp;pid=S0034-75072022000300006&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.sld.cu/scielo.php?script=sci_abstract&amp;pid=S0034-75072022000300006&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.sld.cu/scielo.php?script=sci_pdf&amp;pid=S0034-75072022000300006&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[RESUMEN  Introducción:  La enfermedad periodontal comprende un conjunto de trastornos asociados a la inflamación y a la pérdida de estructuras del soporte dental de origen infeccioso multifactorial. La investigación científica expone un abanico de cepas bacterianas probióticas en el tratamiento periodontal, con propiedades en la inhibición del crecimiento de periodontopatógenos, y mejoras significativas en los parámetros clínicos, cuando se combina con el tratamiento periodontal mecánico.  Objetivo: Describir el efecto de la terapia combinada entre el tratamiento periodontal mecánico tradicional y un gel probiótico multicepa, aplicado a un caso de periodontitis.  Presentación de caso:  Paciente femenino de 53 años de edad, procedente de la comunidad de El Portachuelo, zona rural aledaña a la ciudad de Mérida. Presentó agrandamiento gingival, enrojecimiento y dolor espontáneo en la encía palatina, con concomitantes de sangrado y exudado purulento desde hace seis meses. La realización de un examen clínico periodontal, análisis radiográfico y análisis microbiológico permitieron diagnosticar periodontitis estadio IV grado B. Se aplicó tratamiento periodontal convencional no quirúrgico en combinación con cepas probióticas de Lactobacillus rhamnosus, L acidophilus y L. plantarum, en presentación de un gel adhesivo para la aplicación supra y subgingival y en suspensión vía oral para obtener un efecto sistémico durante 45 días. Los resultados obtenidos fueron favorables con mejoramiento de los parámetros clínicos como índice de sangrado periodontal y profundidad de los sacos periodontales.  Conclusiones:  En concordancia con diversos estudios, se ha demostrado que la terapia probiótica puede ser usada como tratamiento coadyuvante en casos de periodontitis. Se observa una franca y rápida mejoría al utilizar terapias multicepas.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[ABSTRACT  Introduction:  Periodontal disease comprises a set of disorders associated with inflammation and the loss of dental support structures of multifactorial infectious origin. Scientific research exposes a range of probiotic bacterial strains in periodontal treatment, with properties in inhibiting the growth of periodontal pathogens, and significant improvements in clinical parameters, when combined with mechanical periodontal treatment.  Objective:  Describe the effect of combined therapy between traditional mechanical periodontal treatment and a multi-strain probiotic gel, applied to a case of periodontitis.  Case presentation:  A 53-year-old female patient from the community El Portachuelo, a rural area next to the city of Mérida. She presented gingival enlargement, redness and spontaneous pain in the palatine gum, with concomitant bleeding and purulent exudate for six months. A clinical periodontal examination, radiographic analysis and microbiological analysis made it possible to diagnose stage IV grade B periodontitis. Conventional non-surgical periodontal treatment was applied in combination with probiotic strains of Lactobacillus rhamnosus, L. acidophilus and L. plantarum, in presentation of an adhesive gel for supra and subgingival application and in oral suspension to obtain a systemic effect for 45 days. The results obtained were favorable with improvement of clinical parameters such as periodontal bleeding index and depth of periodontal sacs.  Conclusions:  In accordance with several studies, it has been shown that probiotic therapy can be used as an adjuvant treatment in cases of periodontitis. A clear and rapid improvement is observed when using multi-strain therapies.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[probióticos]]></kwd>
<kwd lng="es"><![CDATA[periodontitis]]></kwd>
<kwd lng="es"><![CDATA[Lactobacillus]]></kwd>
<kwd lng="es"><![CDATA[terapia combinada]]></kwd>
<kwd lng="es"><![CDATA[protocolos clínicos]]></kwd>
<kwd lng="en"><![CDATA[probiotics]]></kwd>
<kwd lng="en"><![CDATA[periodontitis]]></kwd>
<kwd lng="en"><![CDATA[Lactobacillus]]></kwd>
<kwd lng="en"><![CDATA[combination therapy]]></kwd>
<kwd lng="en"><![CDATA[clinical protocols]]></kwd>
</kwd-group>
</article-meta>
</front><back>
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