<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>0034-7523</journal-id>
<journal-title><![CDATA[Revista Cubana de Medicina]]></journal-title>
<abbrev-journal-title><![CDATA[Rev cubana med]]></abbrev-journal-title>
<issn>0034-7523</issn>
<publisher>
<publisher-name><![CDATA[Centro Nacional de Información de Ciencias MédicasEditorial Ciencias Médicas]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S0034-75232019000400004</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Caracterización clínico-espirométrica de pacientes asmáticos con síntomas nocturnos]]></article-title>
<article-title xml:lang="en"><![CDATA[Clinical-spirometric characterization of asthmatic patients with nocturnal symptoms]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Díaz Luis]]></surname>
<given-names><![CDATA[Osbel]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Legrá Despaigne]]></surname>
<given-names><![CDATA[Adis]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Fernández Olivera]]></surname>
<given-names><![CDATA[Norma]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Sarduy Paneque]]></surname>
<given-names><![CDATA[Manuel Arbelio]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Terry Valles]]></surname>
<given-names><![CDATA[Otilia María]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Morales Jiménez]]></surname>
<given-names><![CDATA[Emilio Luis]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Hospital Neumológico Docente Benéfico-Jurídico  ]]></institution>
<addr-line><![CDATA[La Habana ]]></addr-line>
<country>Cuba</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>12</month>
<year>2019</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>12</month>
<year>2019</year>
</pub-date>
<volume>58</volume>
<numero>4</numero>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://scielo.sld.cu/scielo.php?script=sci_arttext&amp;pid=S0034-75232019000400004&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.sld.cu/scielo.php?script=sci_abstract&amp;pid=S0034-75232019000400004&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.sld.cu/scielo.php?script=sci_pdf&amp;pid=S0034-75232019000400004&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[RESUMEN  Introducción:  Los síntomas nocturnos son frecuentes en asmáticos y pueden relacionarse con la gravedad, el grado de control del asma y la función pulmonar.  Objetivos:  Determinar las características demográficas, clínicas y espirométricas de pacientes asmáticos con síntomas nocturnos, que acuden a consulta externa de neumología. Métodos: Se realizó un estudio descriptivo transversal en 50 pacientes asmáticos con síntomas nocturnos, atendidos por consulta externa en el Hospital Neumológico Benéfico Jurídico, en el período comprendido de mayo de 2017 a mayo de 2018.  Resultados:  Predominó el sexo femenino (74,0 %), la edad entre 40 y 59 años (52,0 %), los antecedentes familiares de asma o alergia (60,0 %) y múltiples comorbilidades asociadas (78,0 %). La hipersomnia diurna estuvo presente en 80,0 % de los casos, con una frecuencia significativamente elevada en pacientes con asma persistente moderada y severa, disminución de la reversibilidad aguda al broncodilatador, mal control de la enfermedad y limitación de la actividad física.  Conclusiones:  Los síntomas nocturnos en los pacientes asmáticos son frecuentes y se relacionan con la hipersomnia diurna, la gravedad del asma, el grado de control, la respuesta al broncodilatador y limitación de la actividad física.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[ABSTRACT  Introduction:  Nighttime symptoms are frequent in asthmatics and can be related to severity, degree of asthma control and lung function.  Objectives:  To determine the demographic, clinical and spirometric characteristics of asthmatic patients with nocturnal symptoms, who go to an outpatient pulmonology clinic.  Methods:  A descriptive cross-sectional study was conducted in 50 asthmatic patients with nocturnal symptoms, they were assisted in the outpatient consultation at the Hospital Neumológico Benéfico Jurídico, from May 2017 to May 2018.  Results:  Female sex (74.0 %), age ranging 40 and 59 years (52.0 %), family history of asthma or allergy (60.0%) and multiple associated comorbidities (78.0 %) predominated. Daytime hypersomnia was present in 80.0 % of cases, with significantly elevated frequency in patients with moderate and severe persistent asthma, decreased acute reversibility to the bronchodilator, poor disease control, and limited physical activity.  Conclusions:  Nocturnal symptoms in asthmatic patients are frequent and are related to daytime hypersomnia, asthma severity, degree of control, response to the bronchodilator and limitation of physical activity.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[Síntomas nocturnos]]></kwd>
<kwd lng="es"><![CDATA[hipersomnia diurna]]></kwd>
<kwd lng="es"><![CDATA[grado de control del asma]]></kwd>
<kwd lng="es"><![CDATA[gravedad del asma]]></kwd>
<kwd lng="es"><![CDATA[respuesta al broncodilatador]]></kwd>
<kwd lng="en"><![CDATA[nocturnal symptoms]]></kwd>
<kwd lng="en"><![CDATA[daytime hypersomnia]]></kwd>
<kwd lng="en"><![CDATA[degree of asthma control]]></kwd>
<kwd lng="en"><![CDATA[asthma severity]]></kwd>
<kwd lng="en"><![CDATA[response to the bronchodilator]]></kwd>
</kwd-group>
</article-meta>
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