<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>0034-7523</journal-id>
<journal-title><![CDATA[Revista Cubana de Medicina]]></journal-title>
<abbrev-journal-title><![CDATA[Rev. Cuban de Med]]></abbrev-journal-title>
<issn>0034-7523</issn>
<publisher>
<publisher-name><![CDATA[Centro Nacional de Información de Ciencias MédicasEditorial Ciencias Médicas]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S0034-75232022000400014</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Factores relacionados con la letalidad de la enfermedad pulmonar obstructiva crónica exacerbada]]></article-title>
<article-title xml:lang="en"><![CDATA[Factors related to lethality in exacerbated chronic obstructive pulmonary disease]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Elías Sierra]]></surname>
<given-names><![CDATA[Reinaldo]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Elías Armas]]></surname>
<given-names><![CDATA[Karla Sucet]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Choo Ubals]]></surname>
<given-names><![CDATA[Tania]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Bordelois Abdo]]></surname>
<given-names><![CDATA[Max Santiago]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Hospital General Docente &#8220;Dr. Agostinho Neto&#750;  ]]></institution>
<addr-line><![CDATA[ Guantánamo]]></addr-line>
<country>Cuba</country>
</aff>
<aff id="Af2">
<institution><![CDATA[,Policlínica &#8220;Omar Ranedo Pubillones&#750;  ]]></institution>
<addr-line><![CDATA[ Guantánamo]]></addr-line>
<country>Cuba</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>12</month>
<year>2022</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>12</month>
<year>2022</year>
</pub-date>
<volume>61</volume>
<numero>4</numero>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://scielo.sld.cu/scielo.php?script=sci_arttext&amp;pid=S0034-75232022000400014&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.sld.cu/scielo.php?script=sci_abstract&amp;pid=S0034-75232022000400014&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.sld.cu/scielo.php?script=sci_pdf&amp;pid=S0034-75232022000400014&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[RESUMEN  Introducción: La letalidad de la enfermedad pulmonar obstructiva crónica agudizada es un problema no resuelto en las unidades de cuidados intensivos.  Objetivo:  Identificar los factores relacionados con la letalidad de pacientes con exacerbación de la enfermedad pulmonar obstructiva crónica, egresados de la unidad de cuidados intensivos en el Hospital Dr. &#8220;Agostinho Neto&#750; de Guantánamo, en el período comprendido de 2019 a 2020.  Métodos:  Se realizó un estudio tipo caso-control donde se utilizaron variables sociodemográficas (edad, sexo, estado nutricional, comorbilidad, hábitos tóxicos), y otras en relación con la enfermedad pulmonar obstructiva crónica (fenotipo, severidad, diagnósticos asociados, indicadores gasométricos, tratamiento con ventilación mecánica, complicaciones, estado al egreso, causas de muerte).  Resultados: El mayor número de pacientes se caracterizó por: tener más de 60 años (n=45), ser hombres (n=46), con más de 10 años de evolución de la enfermedad (n=37), bajo peso (n=35), y tres o más comorbilidades (n=41) y la más común fue el corazón pulmonar crónico (n=36), una puntuación Sequential Organ Failure Assessment Score y Acute Physiology and Chronic Health Evaluation II) elevada, fumadores (n=47), entre otro aspectos.  Conclusiones: Los factores más asociados con la letalidad fueron la puntuación de la escala Sequential Organ Failure Assessment Score) igual o mayor de 16 puntos, la hipoxemia igual o mayor de 60 mmHg y la realización de traqueostomía 5 días o más de ventilación mecánica.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[ABSTRACT  Introduction:  The lethality of exacerbated chronic obstructive pulmonary disease is an unresolved problem in intensive care units.  Objective:  To identify the factors related to the lethality of patients with exacerbation of chronic obstructive pulmonary disease, discharged from the intensive care unit in the Dr. &#8220;Agostinho Neto&#750; Hospital of Guantánamo, from 2019 to 2020.  Methods:  A case-control study was carried out using sociodemographic variables (age, gender, nutritional status, comorbidity, toxic habits), and other variables related to chronic obstructive pulmonary disease (phenotype, severity, associated diagnoses, gasometric indicators, treatment with mechanical ventilation, complications, status at discharge, causes of death).  Results:  The largest number of patients were characterized by: being over 60 years old (n=45), male (n=46), with more than 10 years of disease evolution (n=37), underweight (n=35), and three or more comorbidities (n=41) and the most common was chronic pulmonary heart (n=36), high Sequential Organ Failure Assessment Score and Acute Physiology and Chronic Health Evaluation II), smokers (n=47), among other aspects.  Conclusions:  The factors most associated with lethality were Sequential Organ Failure Assessment Score) score equal to or greater than 16 points, hypoxemia equal to or greater than 60 mmHg, and performance of tracheostomy 5 or more days of mechanical ventilation.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[enfermedades pulmonar obstructiva crónica]]></kwd>
<kwd lng="es"><![CDATA[mortalidad]]></kwd>
<kwd lng="es"><![CDATA[análisis de riesgo]]></kwd>
<kwd lng="en"><![CDATA[chronic obstructive pulmonary disease]]></kwd>
<kwd lng="en"><![CDATA[mortality]]></kwd>
<kwd lng="en"><![CDATA[risk analysis]]></kwd>
</kwd-group>
</article-meta>
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