<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>0034-7531</journal-id>
<journal-title><![CDATA[Revista Cubana de Pediatría]]></journal-title>
<abbrev-journal-title><![CDATA[Rev Cubana Pediatr]]></abbrev-journal-title>
<issn>0034-7531</issn>
<publisher>
<publisher-name><![CDATA[Centro Nacional de Información de Ciencias MédicasEditorial Ciencias Médicas]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S0034-75312020000300010</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Caracterización clínica epidemiológica de pacientes pediátricos con zika en epidemia]]></article-title>
<article-title xml:lang="en"><![CDATA[Clinical-epidemiological characterization of pediatric patients with zika in epidemic]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Tejeda Hernández]]></surname>
<given-names><![CDATA[Olga Olivia]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Amaro Rodríguez]]></surname>
<given-names><![CDATA[Lázara]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Sosa Palacios]]></surname>
<given-names><![CDATA[Oramis]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Hospital Pediátrico &#8220;Leonor Pérez&#8221; Departamento de Pediatría ]]></institution>
<addr-line><![CDATA[La Habana ]]></addr-line>
<country>Cuba</country>
</aff>
<aff id="Af2">
<institution><![CDATA[,Hospital Pediátrico Docente &#8220;William Soler&#8221; Departamento de Pediatría ]]></institution>
<addr-line><![CDATA[La Habana ]]></addr-line>
<country>Cuba</country>
</aff>
<aff id="Af3">
<institution><![CDATA[,Hospital Pediátrico Docente &#8220;William Soler&#8221; Departamento Docente ]]></institution>
<addr-line><![CDATA[La Habana ]]></addr-line>
<country>Cuba</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>09</month>
<year>2020</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>09</month>
<year>2020</year>
</pub-date>
<volume>92</volume>
<numero>3</numero>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://scielo.sld.cu/scielo.php?script=sci_arttext&amp;pid=S0034-75312020000300010&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.sld.cu/scielo.php?script=sci_abstract&amp;pid=S0034-75312020000300010&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.sld.cu/scielo.php?script=sci_pdf&amp;pid=S0034-75312020000300010&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[RESUMEN  Introducción:  El zika es considerado una virosis emergente, nunca antes presente en Cuba.  Objetivo:  Caracterizar desde el punto de vista clínico epidemiológico a pacientes pediátricos con zika confirmado.  Métodos:  Estudio descriptivo transversal realizado en el Hospital Pediátrico &#8220;Leonor Pérez&#8221; entre 2016- 2017, en el transcurso de la epidemia. Se analizaron 140 historias clínicas de pacientes con zika confirmado por reacción en cadena de la polimerasa en suero y orina. Se midieron variables clínicas, de laboratorio y se calculó la tasa asistida.  Resultados:  La tasa asistida fue 44,35 × 100 casos sospechosos. De las historias clínicas analizadas, 72,1 % correspondió al sexo masculino y el grupo de edad de 10 a 15 años. La reacción en cadena de la polimerasa fue positiva en mayor porcentaje en orina que en suero: 52,1 y 40,7 % respectivamente y en correspondencia con el día de toma de la muestra de orina. El exantema estuvo presente en 84,3 % de pacientes y la fiebre en 70 %. El prurito, ojos rojos, cefalea, malestar general, dolor retroocular, odinofagia, artralgia, anorexia y edemas, se observó en menos de 35 % de los casos. Los promedios de los componentes del hemograma con diferencial y la eritrosedimentación fueron normales.  Conclusiones:  El exantema y la fiebre son los síntomas de mayor presencia y el estudio en orina por reacción en cadena de la polimerasa informa mayor número de pacientes positivos que en suero, según el momento del ingreso. Los complementarios de rutina son poco sugerentes de zika en los casos sospechosos.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[ABSTRACT  Introduction:  Zika virus is considerd as an emergent virus with no previous presence in the Cuban population.  Objective:  To characterize clinically patients with confirmed Zika virus.  Methods:  Descriptive cross-sectional study conducted in ´´Leonor Pérez´´ Pediatric Hospital between 2016 and 2017 during the epidemics. There were analyzed 140 clinical records of patients with zika confirmed by chain reaction of polymerase in serum and urine. There were measured clinical and laboratory variables and it was calculated the assisted rate.  Results:  The assisted rate was 44.35 × 100 suspected cases. From the analyzed clinical records, 72.1% corresponded to the male sex and the average age was 10.9 ± 5.5 years. The chain reaction of polimerase was positive in a higher percentage of patients in urine than in serum: 52.1% and 40.7%, respectively and corresponding with the day when the urine sample was taken. Rash was present in 84.3% of the patients and fever in 70.0%. Pruritus, red eyes, cephalalgia, general discomfort, pain behind the eyes, odynophagia, arthralgia, anorexia and edemas were observed in less than 35.0% of the cases. The averages of the components of blood count with differential and the erythrocyte sedimentation were normal.  Conclusions:  Rash and fever are the most frequent symptoms and the study of urine by chain reaction of polimerase informs of a higher number of positive patients than in the study of serum, according to the time of admittion. The routine complementary tests are not suggestive of zika in suspected cases.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[zika]]></kwd>
<kwd lng="es"><![CDATA[clínica]]></kwd>
<kwd lng="es"><![CDATA[epidemiología]]></kwd>
<kwd lng="es"><![CDATA[pediatría]]></kwd>
<kwd lng="en"><![CDATA[zika]]></kwd>
<kwd lng="en"><![CDATA[clinic]]></kwd>
<kwd lng="en"><![CDATA[epidemiology]]></kwd>
<kwd lng="en"><![CDATA[pediatrics]]></kwd>
</kwd-group>
</article-meta>
</front><back>
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