<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>0864-084X</journal-id>
<journal-title><![CDATA[Nucleus]]></journal-title>
<abbrev-journal-title><![CDATA[Nucleus]]></abbrev-journal-title>
<issn>0864-084X</issn>
<publisher>
<publisher-name><![CDATA[CUBAENERGIA]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S0864-084X2020000100039</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Marcaje de arena sílice con 99mTc para la obtención de un radiotrazador sólido]]></article-title>
<article-title xml:lang="en"><![CDATA[Labeling of silica sand with 99mTc for obtaining a solid radiotracer]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Aguilera Corrales]]></surname>
<given-names><![CDATA[Yuri]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Llanes Montesino]]></surname>
<given-names><![CDATA[Luis Enrique]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Díaz Páez]]></surname>
<given-names><![CDATA[Ahmed]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Espino López]]></surname>
<given-names><![CDATA[Raquel]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Instituto Superior de Tecnologías y Ciencias Aplicadas (InSTEC)  ]]></institution>
<addr-line><![CDATA[ La Habana]]></addr-line>
<country>Cuba</country>
</aff>
<aff id="Af2">
<institution><![CDATA[,Centro de Aplicaciones Tecnológicas y Desarrollo Nuclear (CEADEN)  ]]></institution>
<addr-line><![CDATA[Playa La Habana]]></addr-line>
<country>Cuba</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>06</month>
<year>2020</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>06</month>
<year>2020</year>
</pub-date>
<numero>67</numero>
<fpage>39</fpage>
<lpage>43</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://scielo.sld.cu/scielo.php?script=sci_arttext&amp;pid=S0864-084X2020000100039&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.sld.cu/scielo.php?script=sci_abstract&amp;pid=S0864-084X2020000100039&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.sld.cu/scielo.php?script=sci_pdf&amp;pid=S0864-084X2020000100039&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[Resumen Para la obtención de radiotrazadores sólidos de 99mTc actualmente se necesitan nuevos soportes porosos. Estudios anteriores realizados por otros autores mostraron la posibilidad del marcaje con 99mTc de sedimentos de ríos con alto contenido de aluminosilicatos. En el presente trabajo se desarrolló una metodología para el marcaje de arena sílice con el 99mTcO4- para su uso como radiotrazador sólido. Se realizó el marcaje de la arena sílice previamente tratada y sin tratar empleando concentraciones variables de cloruro y fluoruro estañoso como agentes reductores y diferentes tiempos de marcaje. Se evaluó la influencia de la etapa de tratamiento previo de la arena en los rendimientos de retención del Tc obtenidos. Los cambios en la composición de la arena sílice luego de su tratamiento previo se pudieron constatar a partir de la Microscopía Electrónica de Barrido (SEM-EDS). Los resultados sugirieren el empleo de la arena sílice previamente tratada y de fluoruro estañoso como agente reductor, adicionalmente se propusieron modificaciones a la metodología inicial de tratamiento previo de la arena. Se pudo constatar a partir de la técnica SEM-EDS que el aumento del porciento de retención del Tc en la arena luego de su tratamiento, se debe fundamentalmente a los cambios observados en su composición química y en su estructura. Se logró la obtención de un radiotrazador sólido marcado con 99mTc en soporte de arena sílice con un tiempo de preparación estimado de 4 horas y un rendimiento de retención de 74%.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[Abstract To obtain 99mTc solid radiotracers, new porous supports are currently needed. Previous studies carried out by other authors showed the possibility of 99mTc labeling of sediments from rivers with a high content of aluminosilicates. In the present work a methodology for labeling of silica sand with 99mTcO4- as a prospective solid radiotracer was developed. Labeling of the previously treated and untreated silica sand was carried out using variable concentrations of chloride and stannous fluoride as reducing agents and different labeling times. The influence of the pre-treatment stage of the sand on the obtained Tc retention yields was evaluated. The changes in the composition of the silica sand after its previous treatment could be verified from the Scanning Electron Microscopy (SEM-EDS). The results suggested the use of previously treated silica sand and stannous fluoride as a reducing agent, modifications were proposed to the initial methodology of previous treatment of the sand. It was possible to confirm from the SEM-EDS technique that the increase in the percentage of retention of Tc in the sand after its treatment is mainly due to the observed changes in its chemical composition and structure. It was possible to obtain a 99mTc solid radiotracer on support of silica sand with an estimated preparation time of 4 hours and a retention yield of 74%.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[sílice]]></kwd>
<kwd lng="es"><![CDATA[tecnecio 99]]></kwd>
<kwd lng="es"><![CDATA[agentes reductores]]></kwd>
<kwd lng="es"><![CDATA[marcado]]></kwd>
<kwd lng="es"><![CDATA[técnicas de trazadores]]></kwd>
<kwd lng="es"><![CDATA[compuestos marcados]]></kwd>
<kwd lng="en"><![CDATA[silica]]></kwd>
<kwd lng="en"><![CDATA[technetium 99]]></kwd>
<kwd lng="en"><![CDATA[reducing agents]]></kwd>
<kwd lng="en"><![CDATA[labelling]]></kwd>
<kwd lng="en"><![CDATA[tracer techniques]]></kwd>
<kwd lng="en"><![CDATA[labelled compounds]]></kwd>
</kwd-group>
</article-meta>
</front><back>
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