<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>1025-0255</journal-id>
<journal-title><![CDATA[Revista Archivo Médico de Camagüey]]></journal-title>
<abbrev-journal-title><![CDATA[AMC]]></abbrev-journal-title>
<issn>1025-0255</issn>
<publisher>
<publisher-name><![CDATA[Universidad de Ciencias Médicas de Camagüey]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S1025-02552018000500694</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Marcadores serológicos de infección por el virus de la hepatitis B en estudiantes de la Escuela Latinoamericana de Medicina]]></article-title>
<article-title xml:lang="en"><![CDATA[Serological markers of infection for the hepatitis B virus in students of the Latin American School of Medicine]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Gordillo Hernández]]></surname>
<given-names><![CDATA[Aned]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Centro Provincial de Higiene, Epidemiología y Microbiología de La Habana  ]]></institution>
<addr-line><![CDATA[La Habana ]]></addr-line>
<country>Cuba</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>10</month>
<year>2018</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>10</month>
<year>2018</year>
</pub-date>
<volume>22</volume>
<numero>5</numero>
<fpage>694</fpage>
<lpage>707</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://scielo.sld.cu/scielo.php?script=sci_arttext&amp;pid=S1025-02552018000500694&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.sld.cu/scielo.php?script=sci_abstract&amp;pid=S1025-02552018000500694&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.sld.cu/scielo.php?script=sci_pdf&amp;pid=S1025-02552018000500694&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[RESUMEN  Fundamento: la hepatitis B es un importante problema de salud a nivel mundial. Según la OMS, se estima que 2 000 millones de personas han sido infectadas y más de 360 millones son portadores crónicos. El diagnóstico de la hepatitis B se ha realizado a través de técnicas serológicas para detectar diferentes marcadores virales.  Objetivo:  determinar el comportamiento de los marcadores serológicos del virus de la hepatitis B (VHB) en estudiantes de la Escuela Latinoamericana de Medicina durante el primer trimestre de 2017.  Métodos:  se realizó un estudio descriptivo de corte transversal entre enero y marzo de 2017, con estudiantes de la Escuela Latinoamericana de Medicina. Se estudiaron 762 muestras clínicas que se recibieron en el Centro Provincial de Higiene, Epidemiología y Microbiología. Para el diagnóstico se utilizaron los estuches de reactivos UltramicroELISA para detectar anti-HBc total, UltramicroELISA para descubrir HBsAg y su prueba confirmatoria, UltramicroELISA para revelar anticuerpos de tipo IgM al antígeno core y UltramicroELISA para detectar anticuerpos al antígeno de superficie, todos producidos por el Centro de Inmunoensayo de La Habana, Cuba.  Resultados: la mayor prevalencia se encontró en el estadio de infección resuelta, seguido del de ventana inmunológica, infección aguda e infección crónica, para un 5,25 % (n=40) de estudiantes universitarios que han tenido contacto previo con el VHB. Por otra parte, el 94,75 % (n=722) no se identificaron marcadores virales con las pruebas serológicas empleadas, definidos como susceptibles. La positividad para el estadio de infección aguda fue mayor en hombres, mientras que para el estadio de infección crónica fue mayor en mujeres.  Conclusiones:  los resultados obtenidos demuestran la posibilidad de incrementar la eficiencia en el diagnóstico y la vigilancia epidemiológica del VHB.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[ABSTRACT  Background: the hepatitis B is an important worldwide health problem. According to the WHO, it is estimated that 2000 million people have been infected and more of 360 million they are chronic carriers. The diagnosis of the hepatitis B has been done through immunological techniques to detect different viral markers.  Objective: to determine the behavior of the serological markers of the hepatitis B virus (VHB) in students of the Latin American School of Medicine during the first quarter of 2017.  Methods: a descriptive cross section study was carried out between January and March, 2017, with students of the Latin-American School of Medicine. There were studied 762 clinical samples that were received in the Provincial Center of Hygiene, Epidemiology and Microbiology. For the diagnosis the cases of reagents UltramicroELISA were used to detect entire anti-HBc, UltramicroELISA to discover HBsAg and its confirmatory test, UltramicroELISA to reveal antibodies of IgM type to the core antigen and UltramicroELISA to detect antibodies to the surface antigen, all produced by the Center of Immune-trial of Havana, Cuba.  Results: the biggest prevalence found in the stage of resolute infection, followed by the one of immunological window, acute infection and chronic infection, for a 5.25 % (n=40) of university students that have had previous contact with the VHB. On the other hand, in 94.75 % (n=722) they did not identify viral markers with the serologic tests used, defined like susceptible. The positiveness for the stage of acute infection was major in men, while for the stage of chronic infection he was older in women.  Conclusions:  the obtained results demonstrate the possibility of incrementing the efficiency in the diagnosis and the epidemiological surveillance of the VHB.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[BIOMARCADORES]]></kwd>
<kwd lng="es"><![CDATA[PRUEBAS SEROLÓGICAS]]></kwd>
<kwd lng="es"><![CDATA[VIRUS DE LA HEPATITIS B]]></kwd>
<kwd lng="es"><![CDATA[MONITOREO EPIDEMIOLÓGICO]]></kwd>
<kwd lng="es"><![CDATA[ESTUDIANTES DE MEDICINA]]></kwd>
<kwd lng="en"><![CDATA[BIOMARKERS]]></kwd>
<kwd lng="en"><![CDATA[SEROLOGIC TESTS]]></kwd>
<kwd lng="en"><![CDATA[HEPATITIS B VIRUS]]></kwd>
<kwd lng="en"><![CDATA[EPIDEMIOLOGICAL MONITORING]]></kwd>
<kwd lng="en"><![CDATA[STUDENTS, MEDICAL]]></kwd>
</kwd-group>
</article-meta>
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