<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>1028-9933</journal-id>
<journal-title><![CDATA[Revista Información Científica]]></journal-title>
<abbrev-journal-title><![CDATA[Rev. inf. cient.]]></abbrev-journal-title>
<issn>1028-9933</issn>
<publisher>
<publisher-name><![CDATA[Universidad de Ciencias Médicas Guantánamo]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S1028-99332020000200134</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Reacciones cutáneas adversas medicamentosas en el Hospital General Docente &#8220;Dr. Agostinho Neto&#8221;, Guantánamo 2018-2019]]></article-title>
<article-title xml:lang="en"><![CDATA[Adverse cutaneous reactions to drugs (CDRs) at the General Teaching Hospital &#8220;Dr. Agostinho Neto&#8221;, Guantánamo 2018-2019]]></article-title>
<article-title xml:lang="pt"><![CDATA[Reações cutâneas adversas a medicamentos no Hospital Geral de Ensino &#8220;Dr. Agostinho Neto&#8221;, Guantánamo 2018-2019]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Rojas-Caraballo]]></surname>
<given-names><![CDATA[Nivia]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Machado-Mora]]></surname>
<given-names><![CDATA[Yarianna]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Lagos-Ordoñez]]></surname>
<given-names><![CDATA[Kathy Julissa]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Bordelois-Abdo]]></surname>
<given-names><![CDATA[José Antonio]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Mozo-Bigñotte]]></surname>
<given-names><![CDATA[Aymeé]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Hospital General Docente &#8220;Dr. Agostinho Neto&#8221;  ]]></institution>
<addr-line><![CDATA[ Guantánamo]]></addr-line>
<country>Cuba</country>
</aff>
<aff id="Af2">
<institution><![CDATA[,Hospital Escuela Universitaria de Honduras  ]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
<country>Honduras</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>04</month>
<year>2020</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>04</month>
<year>2020</year>
</pub-date>
<volume>99</volume>
<numero>2</numero>
<fpage>134</fpage>
<lpage>141</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://scielo.sld.cu/scielo.php?script=sci_arttext&amp;pid=S1028-99332020000200134&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.sld.cu/scielo.php?script=sci_abstract&amp;pid=S1028-99332020000200134&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.sld.cu/scielo.php?script=sci_pdf&amp;pid=S1028-99332020000200134&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[RESUMEN  Introducción: En Guantánamo no se encuentra ningún estudio que aborde las reacciones cutáneas adversas medicamentosas (RCAM), necesidad sentida por el claustro de dermatólogos del territorio.  Objetivo: Caracterizar las reacciones cutáneas adversas medicamentosas en pacientes atendidos en el Servicio de Dermatología del Hospital General Docente &#8220;Dr. Agostinho Neto&#8221; de Guantánamo en el período 2018-2019.  Método:  Se realizó un estudio descriptivo y transversal con todos los pacientes (N=75) con el diagnóstico de reacciones cutáneas adversas medicamentosas remitidos a la consulta de Dermatología del Hospital General Docente &#8220;Dr. Agostinho Neto&#8221;, se precisó el medicamento que originó la reacción, diagnóstico clínico, tipo de reacción, tiempo de evolución desde la ingestión del fármaco hasta la aparición de los síntomas, número de reacciones y conducta médica.  Resultados: Estas reacciones fueron más comunes en pacientes que utilizaron ibuprofeno( 18,7 %), la forma clínica más frecuente fue el eritema multiforme menor (82,7 %), sobre todo fueron reacciones leves (94,8 %), que se presentaron con más frecuencia a los 10 ± 2,1 días de utilizar el fármaco. El 97,4 % de los pacientes se trató de modo ambulatorio.  Conclusiones: Las RCAM no constituyen en un problema de salud en el Servicio de Dermatología del Hospital General Docente &#8220;Dr. Agostinho Neto&#8221;, éstas presentan un espectro clínico coherente con lo que se refrenda en la literatura científica, pero se connota que el diagnóstico no suele ser con la precocidad que se demanda, pues los pacientes suelen solicitar evaluación médica luego de un periodo superior a siete días.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[ABSTRACT  Introduction: No studies in reference to adverse cutaneous reactions to drugs (CDRs) have been found at Guantanamo, need felt by the local dermatology faculty.  Objective: Characterize the adverse cutaneous reactions to drugs in patients treated at the Dermatology Service of the General Teaching Hospital "Dr. Agostinho Neto" in Guantanamo, period 2018-2019.  Method: A descriptive and transversal study was carried out with all patients (N=75) with the diagnosis of adverse cutaneous reactions to drugs referred to the Dermatology Clinic of the General Teaching Hospital "Dr. Agostinho Neto, the drug that caused the reaction, clinical diagnosis, type of reaction, time from ingestion of the drug until the symptoms appeared, number of reactions and medical behaviour were specified.  Results:  These reactions were more common in patients using ibuprofen (18.7%), the most frequent clinical form was erythema multiforme minor (82.7%), above all were mild reactions (94.8%), which occurred more often at 10 ± 2.1 days of using the drug. 97.4% of patients were treated on an outpatient basis.  Conclusions: The (CDRs) does not constitute a health problem in the Dermatology Service of the General Teaching Hospital "Dr. Agostinho Neto", they present a clinical spectrum consistent with what is endorsed in the scientific literature, but it is noted that the diagnosis is not usually as early as demand, because patients usually request medical evaluation after a period exceeding seven days.]]></p></abstract>
<abstract abstract-type="short" xml:lang="pt"><p><![CDATA[RESUMO  Introdução:  Em Guantánamo, não há estudos que abordem as reações cutâneas adversas a medicamentos (RCAM), uma necessidade sentida pelo claustro dos dermatologistas no território.  Objetivo:  Caracterizar as reações cutâneas adversas a medicamentos em pacientes atendidos no Serviço de Dermatologia do Hospital Geral de Ensino &#8220;Dr. Agostinho Neto&#8221; de Guantánamo no período 2018-2019.  Método:  Foi realizado um estudo descritivo e transversal com todos os pacientes (N=75) com diagnóstico de reações cutâneas adversas a medicamentos encaminhados ao serviço de Dermatologia do Hospital Geral de Ensino "Dr. Agostinho Neto&#8221;, o medicamento que causou a reação, diagnóstico clínico, tipo de reação, tempo de evolução da ingestão do medicamento até o aparecimento de sintomas, número de reações e comportamento médico.  Resultados:  Essas reações foram mais comuns em pacientes que usaram ibuprofeno (18,7%), a forma clínica mais frequente foi eritema multiforme menor (82,7%), principalmente reações leves (94,8%), apresentou com maior frequência dentro de 10 ± 2,1 dias após o uso do medicamento. 97,4% dos pacientes foram tratados ambulatorialmente.  Conclusões:  As RCAMs não constituem um problema de saúde no Serviço de Dermatologia do Hospital Geral de Ensino &#8220;Dr. Agostinho Neto&#8221;, estes apresentam um espectro clínico consistente com o que é endossado na literatura científica, mas há conotação de que o diagnóstico geralmente não é com a demanda precoce, uma vez que os pacientes geralmente solicitam avaliação médica após um período superior a sete dias]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[reacciones cutáneas]]></kwd>
<kwd lng="es"><![CDATA[reacciones adversas medicamentosas]]></kwd>
<kwd lng="es"><![CDATA[toxicodermias]]></kwd>
<kwd lng="en"><![CDATA[cutaneous reactions]]></kwd>
<kwd lng="en"><![CDATA[adverse cutaneous reactions to drugs]]></kwd>
<kwd lng="en"><![CDATA[toxicodermas]]></kwd>
<kwd lng="pt"><![CDATA[reações cutâneas]]></kwd>
<kwd lng="pt"><![CDATA[reações]]></kwd>
</kwd-group>
</article-meta>
</front><back>
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