<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>1028-9933</journal-id>
<journal-title><![CDATA[Revista Información Científica]]></journal-title>
<abbrev-journal-title><![CDATA[Rev. inf. cient.]]></abbrev-journal-title>
<issn>1028-9933</issn>
<publisher>
<publisher-name><![CDATA[Universidad de Ciencias Médicas Guantánamo]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S1028-99332023000100065</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Influencia de la enfermedad periodontal en la aterosclerosis]]></article-title>
<article-title xml:lang="en"><![CDATA[Influence of periodontal disease on aterosclerosis]]></article-title>
<article-title xml:lang="pt"><![CDATA[Influência da doença periodontal na aterosclerose]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Miranda-Anchundia]]></surname>
<given-names><![CDATA[Andrea Katherine]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Valbuena-Salazar]]></surname>
<given-names><![CDATA[Gabriela Alejandra]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Zambrano-Salazar]]></surname>
<given-names><![CDATA[Denisse Francisca]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Universidad Regional Autónoma de Los Andes  ]]></institution>
<addr-line><![CDATA[ Quevedo]]></addr-line>
<country>Ecuador</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>00</month>
<year>2023</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>00</month>
<year>2023</year>
</pub-date>
<volume>102</volume>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://scielo.sld.cu/scielo.php?script=sci_arttext&amp;pid=S1028-99332023000100065&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.sld.cu/scielo.php?script=sci_abstract&amp;pid=S1028-99332023000100065&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.sld.cu/scielo.php?script=sci_pdf&amp;pid=S1028-99332023000100065&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[RESUMEN  Introducción: La enfermedad periodontal ha sido identificada como un factor de riesgo para enfermedades del corazón. La falta de hábitos de higiene bucal asociados a factores de riesgo puede conducir al desarrollo de periodontitis, lo que conducirá a un aumento de mediadores inflamatorios en la sangre, lo que es un riesgo potencial para el desarrollo del proceso de aterosclerosis.  Objetivo: Evaluar en la literatura la influencia de la enfermedad periodontal en las enfermedades cardiovasculares, especialmente en relación con la aterosclerosis.  Método: Consistió en una búsqueda en libros y artículos científicos, con la utilización de palabras clave asociadas, así como artículos seleccionados en las bases de datos SciELO, PubMed, Scopus, de lo cual se obtuvieron alrededor de 40 bibliografías, que fueron decantadas a 35, de ellas el 50 % actualizadas. Resultados: estudios de metaanálisis apoyan una relación causal entre la enfermedad periodontal y la cardiopatía, lo que demuestra que el riesgo de desarrollar algunas complicaciones vasculares se encontró aumentado en pacientes con problemas periodontales.  Conclusiones:  Se hace relevante evaluar la relación de estas enfermedades y los mecanismos implicados, para poder elaborar medidas preventivas.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[ABSTRACT  Introduction:  Periodontal disease has been identified as a risk factor for heart disease. The lack of oral hygiene habits associated with risk factors can lead to the development of periodontitis, which will lead to an increase in inflammatory mediators in the blood, which is a potential risk for the development of the atherosclerosis process.  Objective:  To evaluate in the literature the influence of periodontal disease on cardiovascular diseases, especially in relation to atherosclerosis.  Method:  It consisted of a search in books and scientific articles, with the use of associated keywords, as well as selected articles in the SciELO, PubMed, Scopus databases, from which around 40 bibliographies were obtained, which were narrowed down to 35, of them 50% updated.  Results:  Meta-analysis studies support a causal relationship between periodontal disease and heart disease, demonstrating that the risk of developing some vascular complications was found to be increased in patients with periodontal problems.  Final considerations:  It is relevant to evaluate the relationship between these diseases and the mechanisms involved, in order to develop preventive measures.]]></p></abstract>
<abstract abstract-type="short" xml:lang="pt"><p><![CDATA[RESUMO  Introdução:  A doença periodontal tem sido apontada como fator de risco para doenças cardíacas. A falta de hábitos de higiene bucal associada a fatores de risco pode levar ao desenvolvimento de periodontite, o que levará ao aumento de mediadores inflamatórios no sangue, o que representa um risco potencial para o desenvolvimento do processo de aterosclerose.  Objetivo:  Avaliar na literatura a influência da doença periodontal nas doenças cardiovasculares, principalmente em relação à aterosclerose.  Método:  Consistiu na busca em livros e artigos científicos, com utilização de palavras-chave associadas, bem como em artigos selecionados nas bases de dados SciELO, PubMed, Scopus, dos quais foram obtidas cerca de 40 bibliografias, que foram reduzidas a 35, de eles 50% atualizados.  Resultados:  Estudos de meta-análise apoiam uma relação causal entre doença periodontal e doença cardíaca, demonstrando que o risco de desenvolver algumas complicações vasculares foi aumentado em pacientes com problemas periodontais.  Considerações finais:  É relevante avaliar a relação entre estas doenças e os mecanismos envolvidos, para desenvolver medidas preventivas.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[aterosclerosis]]></kwd>
<kwd lng="es"><![CDATA[enfermedad periodontal]]></kwd>
<kwd lng="es"><![CDATA[factor de riesgo]]></kwd>
<kwd lng="es"><![CDATA[periodontitis]]></kwd>
<kwd lng="en"><![CDATA[atherosclerosis]]></kwd>
<kwd lng="en"><![CDATA[periodontal disease]]></kwd>
<kwd lng="en"><![CDATA[risk factor]]></kwd>
<kwd lng="en"><![CDATA[periodontitis]]></kwd>
<kwd lng="pt"><![CDATA[aterosclerose]]></kwd>
<kwd lng="pt"><![CDATA[doença periodontal]]></kwd>
<kwd lng="pt"><![CDATA[fator de risco]]></kwd>
<kwd lng="pt"><![CDATA[periodontite]]></kwd>
</kwd-group>
</article-meta>
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