<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>1029-3019</journal-id>
<journal-title><![CDATA[MEDISAN]]></journal-title>
<abbrev-journal-title><![CDATA[MEDISAN]]></abbrev-journal-title>
<issn>1029-3019</issn>
<publisher>
<publisher-name><![CDATA[Centro Provincial de Información de Ciencias Médicas]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S1029-30192018000800674</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Reacciones adversas a medicamentos antirretrovirales en pacientes con virus de la inmunodeficiencia humana]]></article-title>
<article-title xml:lang="en"><![CDATA[Adverse reactions to antirretroviral drugs in patients with the human inmunodeficiency virus]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Mendo Alcolea]]></surname>
<given-names><![CDATA[Neity]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Mesa Perez]]></surname>
<given-names><![CDATA[Eduardo de Jesús]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Neyra Barrios]]></surname>
<given-names><![CDATA[Rafael]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Berenguer Gournaluses]]></surname>
<given-names><![CDATA[Lázaro]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Nieto Muñiz]]></surname>
<given-names><![CDATA[Graciela]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Universidad de Ciencias Médicas  ]]></institution>
<addr-line><![CDATA[Santiago de Cuba ]]></addr-line>
<country>Cuba</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>10</month>
<year>2018</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>10</month>
<year>2018</year>
</pub-date>
<volume>22</volume>
<numero>8</numero>
<fpage>674</fpage>
<lpage>682</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://scielo.sld.cu/scielo.php?script=sci_arttext&amp;pid=S1029-30192018000800674&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.sld.cu/scielo.php?script=sci_abstract&amp;pid=S1029-30192018000800674&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.sld.cu/scielo.php?script=sci_pdf&amp;pid=S1029-30192018000800674&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[RESUMEN Se efectuó un estudio descriptivo y transversal de 40 pacientes con VIH pertenecientes al Policlínico Docente &#8220;Frank País García&#8221; de Santiago de Cuba, con vistas a identificar las reacciones adversas a medicamentos antirretrovirales durante el primer semestre de 2018. En la casuística, la mayoría de las notificaciones las realizaron los especialistas en Medicina General Integral (61,4 %), seguidos por los de Medicina Interna y los licenciados en Enfermería (8,8 y 17,6 %, respectivamente); asimismo, entre los efectos adversos predominantes figuraron las náuseas, la cefalea y los mareos, fundamentalmente con los esquemas terapéuticos constituidos por lamivudina-zidovudina-nevirapina y zidovudina-nevirapina-efavirenz. Se concluye que durante el tratamiento antirretroviral la mayoría de dichas reacciones fueron clasificadas como definitivas, independientemente del esquema terapéutico prescrito y las enfermedades concomitantes.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[ABSTRACT A descriptive and cross sectional study of 40 patients with HIV belonging to the Teaching Polyclinic "Frank País García" in Santiago de Cuba was carried out with the aim of identifying the adverse reactions to antirretroviral drugs during the first semester of 2018. Most of the notifications were carried out by specialists in Comprehensive General Medicine (61,4%) in the case material, followed by those of Internal Medicine and Licentiate in Nursing (8,8 and 17,6%, respectively); also, among the predominant adverse effects there were nauseas, migraine and sickness, fundamentally with the therapeutic schemes constituted by lamivudina-zidovudina-nevirapina and zidovudina-nevirapina-efavirenz. It is concluded that during antirretroviral treatment most of these reactions were classified as definitive, independently of the prescribed therapeutic scheme and the concomitant diseases.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[VIH]]></kwd>
<kwd lng="es"><![CDATA[medicamentos antirretrovirales]]></kwd>
<kwd lng="es"><![CDATA[reacción adversa]]></kwd>
<kwd lng="es"><![CDATA[farmacovigilancia]]></kwd>
<kwd lng="es"><![CDATA[atención primaria de salud]]></kwd>
<kwd lng="en"><![CDATA[HIV]]></kwd>
<kwd lng="en"><![CDATA[antirretroviral drugs]]></kwd>
<kwd lng="en"><![CDATA[adverse reaction]]></kwd>
<kwd lng="en"><![CDATA[pharmacosurveillance]]></kwd>
<kwd lng="en"><![CDATA[primary health care]]></kwd>
</kwd-group>
</article-meta>
</front><back>
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