<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>1029-3019</journal-id>
<journal-title><![CDATA[MEDISAN]]></journal-title>
<abbrev-journal-title><![CDATA[MEDISAN]]></abbrev-journal-title>
<issn>1029-3019</issn>
<publisher>
<publisher-name><![CDATA[Centro Provincial de Información de Ciencias Médicas]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S1029-30192019000300534</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Evolución histórica de las técnicas estadísticas y las metodologías para el estudio de la causalidad en ciencias médicas]]></article-title>
<article-title xml:lang="en"><![CDATA[Historical changes of the statistical techniques and the methodologies for the study of the causality in medical sciences]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Sagaró del Campo]]></surname>
<given-names><![CDATA[Nelsa María]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Zamora Matamoros]]></surname>
<given-names><![CDATA[Larisa]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Universidad de Ciencias Médicas  ]]></institution>
<addr-line><![CDATA[Santiago de Cuba ]]></addr-line>
<country>Cuba</country>
</aff>
<aff id="Af2">
<institution><![CDATA[,Universidad de Oriente  ]]></institution>
<addr-line><![CDATA[Santiago de Cuba ]]></addr-line>
<country>Cuba</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>06</month>
<year>2019</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>06</month>
<year>2019</year>
</pub-date>
<volume>23</volume>
<numero>3</numero>
<fpage>534</fpage>
<lpage>556</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://scielo.sld.cu/scielo.php?script=sci_arttext&amp;pid=S1029-30192019000300534&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.sld.cu/scielo.php?script=sci_abstract&amp;pid=S1029-30192019000300534&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.sld.cu/scielo.php?script=sci_pdf&amp;pid=S1029-30192019000300534&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[RESUMEN Las técnicas estadísticas constituyen las herramientas matemáticas que permiten el análisis causal de los problemas de salud; de ahí la importancia de conocer cómo ha sido su desarrollo a lo largo del tiempo, por lo cual el objetivo de este trabajo fue elaborar una síntesis de la evolución histórica de las técnicas y metodologías empleadas en la investigación médica en relación con los modelos de causalidad que han primado en cada momento histórico. A tales efectos, se realizó una amplia revisión documental y, para una mejor comprensión, se dividió la evolución en cinco etapas, según el desarrollo alcanzado en las técnicas estadísticas. Asimismo, se describen los principales hechos y las características fundamentales de cada época y se destaca la regresión logística binaria como la técnica más empleada.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[ABSTRACT The statistical techniques constitute the mathematical tools that allow the causal analysis of the health problems; that is why it is import to know about their development through time, reason why the objective of this work was to elaborate a synthesis of the historical course of the techniques and methodologies used in the medical investigation in connection with the causality models that have prevailed in each historical moment. To such effects, a wide documental review was carried out and, for a better understanding, the changes were divided in five stages, according to the development reached in the statistical techniques. Also, the main facts and the fundamental characteristics of each stage are described and the binary logistical regression is highlighted as the most used technique.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[historia de la estadística]]></kwd>
<kwd lng="es"><![CDATA[causalidad en medicina]]></kwd>
<kwd lng="es"><![CDATA[modelos de causalidad]]></kwd>
<kwd lng="es"><![CDATA[técnicas estadísticas]]></kwd>
<kwd lng="es"><![CDATA[análisis estadístico implicativo]]></kwd>
<kwd lng="en"><![CDATA[history of statistics]]></kwd>
<kwd lng="en"><![CDATA[causality in medicine]]></kwd>
<kwd lng="en"><![CDATA[causality models]]></kwd>
<kwd lng="en"><![CDATA[statistical techniques]]></kwd>
<kwd lng="en"><![CDATA[statistical implicative analysis]]></kwd>
</kwd-group>
</article-meta>
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