<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>1029-3019</journal-id>
<journal-title><![CDATA[MEDISAN]]></journal-title>
<abbrev-journal-title><![CDATA[MEDISAN]]></abbrev-journal-title>
<issn>1029-3019</issn>
<publisher>
<publisher-name><![CDATA[Centro Provincial de Información de Ciencias Médicas]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S1029-30192020000400641</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Caracterización clínica, humoral, laparoscópica e histológica de pacientes con anticuerpos contra el virus de la hepatitis C]]></article-title>
<article-title xml:lang="en"><![CDATA[Clinical, humoral, laparoscopic and histologic characterization of patients with antibodies against the hepatitis C virus]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Caro Fernández]]></surname>
<given-names><![CDATA[Miriam Teresa]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Ortega Solano]]></surname>
<given-names><![CDATA[Guillermo]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Martén Marén]]></surname>
<given-names><![CDATA[Daysi]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Suárez Suárez]]></surname>
<given-names><![CDATA[María Jannine]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[González Purón]]></surname>
<given-names><![CDATA[Mari Blanca]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Universidad de Ciencias Médicas Hospital General Docente Dr. Juan Bruno Zayas Alfonso ]]></institution>
<addr-line><![CDATA[Santiago de Cuba ]]></addr-line>
<country>Cuba</country>
</aff>
<aff id="Af2">
<institution><![CDATA[,Universidad de Ciencias Médicas Hospital Infantil Docente Sur Dr. Antonio María Béguez César ]]></institution>
<addr-line><![CDATA[Santiago de Cuba ]]></addr-line>
<country>Cuba</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>08</month>
<year>2020</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>08</month>
<year>2020</year>
</pub-date>
<volume>24</volume>
<numero>4</numero>
<fpage>641</fpage>
<lpage>652</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://scielo.sld.cu/scielo.php?script=sci_arttext&amp;pid=S1029-30192020000400641&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.sld.cu/scielo.php?script=sci_abstract&amp;pid=S1029-30192020000400641&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.sld.cu/scielo.php?script=sci_pdf&amp;pid=S1029-30192020000400641&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[RESUMEN  Introducción: La hepatitis C es una infección viral que puede presentarse como una afección leve, de pocas semanas de duración, o evolucionar hasta una enfermedad hepática crónica.  Objetivo:  Caracterizar a pacientes con anticuerpos contra el virus de la hepatitis C según variables clínicas, humorales, laparoscópicas e histológicas.  Métodos: Se realizó un estudio observacional, descriptivo, de serie de casos, de 150 pacientes con anticuerpos contra el virus de la hepatitis C, atendidos en la consulta de Hepatología del Hospital General Dr. Juan Bruno Zayas Alfonso de Santiago de Cuba desde diciembre de 2017 hasta igual mes de 2019, a los cuales se les realizó una biopsia hepática por laparoscopia. Como medida de resumen se utilizó el porcentaje.  Resultados:  Predominaron el grupo etario de 61-70 años y el sexo femenino. La vía sanguínea resultó ser la de mayor riesgo para la transmisión del virus de la hepatitis C. A pesar de estar infectados, 45,3 % de los pacientes evolucionaron en algunos momentos de la enfermedad con valores de alanina aminotransferasa normales.  Conclusiones: En los estudios laparoscópicos fueron más frecuentes el hígado normal y la hepatitis crónica, a la vez que primaron estas últimas con lesiones leves y moderadas. Se constató la presencia de lesiones hísticas tanto en los pacientes sintomáticos como asintomáticos.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[ABSTRACT  Introduction:  Hepatitis C is a viral infection that can be presented as a light disorder, during few weeks, or become into a chronic hepatic disease.  Objective:  To characterize patients with antibodies against the hepatitis C virus according to clinical, humoral, laparoscopic and histological variables.  Methods: An observational, descriptive, serial cases study, of 150 patients with antibodies against the hepatitis C virus was carried out, they were assisted in the hepatology service of Dr. Juan Bruno Zayas Alfonso General Hospital in Santiago de Cuba from December, 2017 to the same month in 2019, to whom a hepatic biopsy by laparoscopy was carried out. The percentage was used as summary measure.  Results:  There was a prevalence of the 61-70 age group and the female sex. The higher risk for the transmission of hepatitis C virus was by blood. In spite of being infected, the 45.3 % of patients had a clinical course in some moments of the disease with normal alanine aminotransferase values.  Conclusions:  In the laparoscopic studies the normal liver and chronic hepatitis were more frequent, at the same time that these last ones prevailed with light and moderate lesions. The presence of tissue lesions was verified either in the symptomatic or asymptomatic patients.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[virus de la hepatitis C]]></kwd>
<kwd lng="es"><![CDATA[infección viral]]></kwd>
<kwd lng="es"><![CDATA[anticuerpo contra el virus de la hepatitis C]]></kwd>
<kwd lng="en"><![CDATA[hepatitis C virus]]></kwd>
<kwd lng="en"><![CDATA[viral infection]]></kwd>
<kwd lng="en"><![CDATA[antibody against hepatitis C virus]]></kwd>
</kwd-group>
</article-meta>
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