<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>1029-3019</journal-id>
<journal-title><![CDATA[MEDISAN]]></journal-title>
<abbrev-journal-title><![CDATA[MEDISAN]]></abbrev-journal-title>
<issn>1029-3019</issn>
<publisher>
<publisher-name><![CDATA[Centro Provincial de Información de Ciencias Médicas]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S1029-30192020000500810</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Características clinicoepidemiológicas de pacientes con evolución asintomática de la COVID-19 en la provincia de Santiago de Cuba]]></article-title>
<article-title xml:lang="en"><![CDATA[Clinical and epidemiological characteristics of patients with asymptomatic clinical course of COVID-19 in Santiago de Cuba province]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Valdés García]]></surname>
<given-names><![CDATA[Luis Eugenio]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[León Bueno]]></surname>
<given-names><![CDATA[Dayma]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Neira Palacios]]></surname>
<given-names><![CDATA[Arairis]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Jaqueman Dussac]]></surname>
<given-names><![CDATA[Yusmel]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Instituto Finlay de Vacunas  ]]></institution>
<addr-line><![CDATA[La Habana ]]></addr-line>
<country>Cuba</country>
</aff>
<aff id="Af2">
<institution><![CDATA[,Centro Provincial de Higiene, Epidemiología y Microbiología  ]]></institution>
<addr-line><![CDATA[Santiago de Cuba ]]></addr-line>
<country>Cuba</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>10</month>
<year>2020</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>10</month>
<year>2020</year>
</pub-date>
<volume>24</volume>
<numero>5</numero>
<fpage>810</fpage>
<lpage>822</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://scielo.sld.cu/scielo.php?script=sci_arttext&amp;pid=S1029-30192020000500810&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.sld.cu/scielo.php?script=sci_abstract&amp;pid=S1029-30192020000500810&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.sld.cu/scielo.php?script=sci_pdf&amp;pid=S1029-30192020000500810&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[RESUMEN  Introducción:  La COVID-19 es una enfermedad infecciosa causada por el virus SARS-CoV-2, la cual se presenta de forma asintomática en hasta 80 % de los casos a nivel mundial.  Objetivo:  Caracterizar a los pacientes con evolución asintomática de la COVID-19.  Métodos:  Se realizó un estudio observacional, descriptivo y transversal en la provincia de Santiago de Cuba, con recolección retrospectiva de la información, de marzo a mayo del 2020, de 13 pacientes con la enfermedad que no manifestaron cuadro sintomático de esta al establecer el diagnóstico.  Resultados:  De los pacientes que dieron positivo por coronavirus en la provincia, 26,0 % estaban asintomáticos; en estos últimos predominaron los grupos etarios de 20-39 años (38,4 %) y de 60 y más años (30,7 %), así como el sexo femenino (84,6 %). Igualmente, 30,7 % padecía enfermedades crónicas no trasmisibles y 38,5 % resultó ser fuente de contagio a otras personas.  Conclusiones:  La frecuencia de pacientes asintomáticos en Santiago de Cuba fue diferente de la notificada en el resto del país y en otras naciones, lo cual pudo estar condicionado por la no aparición de episodios o brotes y la baja incidencia registrada; no obstante, en el análisis de las variables no existieron discrepancias con los informes sobre pacientes con esta forma clínica de la enfermedad.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[ABSTRACT  Introduction:  The COVID-19 is an infectious disease caused by the SARS-CoV-2 virus, which is presented in an asymptomatic way in up to 80 % of the cases at world level.  Objective:  To characterize the patients with asymptomatic clinical course of the COVID-19.  Methods:  An observational, descriptive and cross-sectional study was carried out in Santiago de Cuba province, with retrospective gathering of the information, from March to May, 2020, belonging to 13 patients with diagnosis of the disease and no symptomatic manifestation of it.  Results:  Of the patients with positive results for coronavirus in the province, 26,0 % were asymptomatic; there was a predominance of the 20-39 years-old (38,4 %), and the 60 and more years (30,7 %) in these age groups, as well as of the female sex (84,6 %). Equally, 30,7 % suffered from non-communicable chronic diseases and 38,5 % turned out to be infection source to other people.  Conclusions:  The frequency of asymptomatic patients in Santiago de Cuba was different from that notified in the rest of the country and in other nations, which could be conditioned by the absence of episodes or outbreaks and the low registered incidence; nevertheless, in the analysis of the variables there were no discrepancies with the reports on patients with this clinical form of the disease.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[COVID-19]]></kwd>
<kwd lng="es"><![CDATA[coronavirus SARS-CoV-2]]></kwd>
<kwd lng="es"><![CDATA[reacción en cadena de la polimerasa]]></kwd>
<kwd lng="es"><![CDATA[enfermedades asintomáticas]]></kwd>
<kwd lng="en"><![CDATA[COVID-19]]></kwd>
<kwd lng="en"><![CDATA[coronavirus SARS-CoV-2]]></kwd>
<kwd lng="en"><![CDATA[polymerase chain reaction]]></kwd>
<kwd lng="en"><![CDATA[asymptomatic diseases]]></kwd>
</kwd-group>
</article-meta>
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