<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>1561-3194</journal-id>
<journal-title><![CDATA[Revista de Ciencias Médicas de Pinar del Río]]></journal-title>
<abbrev-journal-title><![CDATA[Rev Ciencias Médicas]]></abbrev-journal-title>
<issn>1561-3194</issn>
<publisher>
<publisher-name><![CDATA[Editorial Ciencias Médicas]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S1561-31942019000400599</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Plasticidad cerebral, una realidad neuronal]]></article-title>
<article-title xml:lang="en"><![CDATA[Brain Plasticity: a neuronal reality]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Sierra Benítez]]></surname>
<given-names><![CDATA[Enrique Marcos]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[León Pérez]]></surname>
<given-names><![CDATA[Mairianny Quianella]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Hospital Universitario Comandante Faustino Pérez  ]]></institution>
<addr-line><![CDATA[Matanzas ]]></addr-line>
<country>Cuba</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>08</month>
<year>2019</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>08</month>
<year>2019</year>
</pub-date>
<volume>23</volume>
<numero>4</numero>
<fpage>599</fpage>
<lpage>609</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://scielo.sld.cu/scielo.php?script=sci_arttext&amp;pid=S1561-31942019000400599&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.sld.cu/scielo.php?script=sci_abstract&amp;pid=S1561-31942019000400599&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.sld.cu/scielo.php?script=sci_pdf&amp;pid=S1561-31942019000400599&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[RESUMEN  Introducción:  el objeto más complejo descubierto hasta ahora en cualquier parte del universo es el órgano que ocupa el espacio comprendido entre nuestras orejas: el cerebro. No es el elevado número de neuronas individuales lo más relevante del cerebro, sino cómo están organizadas e interconectadas.  Objetivo:  analizar elementos teóricos y experimentales expuestos en la literatura consultada acerca de los mecanismos de plasticidad cerebral.  Métodos:  se realizó un estudio descriptivo a partir de una revisión bibliográfica, desde el punto de vista teórico se utilizaron los métodos histórico-lógico, análisis-síntesis e inductivo-deductivo que permitieron el análisis de las principales teorías generadas por diversos estudios experimentales acera del tema en cuestión.  Desarrollo:  neurocientíficos han estudiado desde entonces este enigma demostrando la existencia por diversos mecanismos de fenómenos que permiten el reordenamiento neuronal y la suplencia de funciones cerebrales en respuesta a diversos eventos patológicos o como resultado del proceso de aprendizaje y memoria.  Conclusiones:  tanto la experimentación animal como los estudios realizados en humanos con el empleo de modernas técnicas no invasivas respaldan las ideas de plasticidad neuronal.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[ABSTRACT  Introduction:  brain is the most complex organ discovered up to date, due to the organization and interconnection of its individual neurons.  Objective:  to analyze theoretical and experimental elements stated in the medical literature reviewed about cerebral plasticity mechanisms.  Methods:  a descriptive study was carried out based on a bibliographic review. From the theoretical point of view historical-logical, analysis-synthesis and inductive-deductive methods were applied, which allowed the analysis of the main theories generated by different experimental studies.  Development:  it has been demonstrated the existence of diverse mechanisms that allocate the neuronal rearrangement and replacement of cerebral functions, in response to diverse pathological events or as a result of learning and memory process.  Conclusions:  both animal testing and studies carried out in human being using modern non-invasive techniques support the ideas of neuronal plasticity.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[PLASTICIDAD]]></kwd>
<kwd lng="es"><![CDATA[PLASTICIDAD NEURONAL]]></kwd>
<kwd lng="es"><![CDATA[SINAPSIS]]></kwd>
<kwd lng="es"><![CDATA[CEREBRO]]></kwd>
<kwd lng="es"><![CDATA[NEUROCIENCIAS]]></kwd>
<kwd lng="en"><![CDATA[PLASTICITY]]></kwd>
<kwd lng="en"><![CDATA[NEURONAL PLASTICITY]]></kwd>
<kwd lng="en"><![CDATA[SYNAPSES]]></kwd>
<kwd lng="en"><![CDATA[CEREBRUM]]></kwd>
<kwd lng="en"><![CDATA[NEUROSCIENCES]]></kwd>
</kwd-group>
</article-meta>
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