<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>1561-3194</journal-id>
<journal-title><![CDATA[Revista de Ciencias Médicas de Pinar del Río]]></journal-title>
<abbrev-journal-title><![CDATA[Rev Ciencias Médicas]]></abbrev-journal-title>
<issn>1561-3194</issn>
<publisher>
<publisher-name><![CDATA[Editorial Ciencias Médicas]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S1561-31942022000100009</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Macroangiopatía diabética y autotransplante de células madre]]></article-title>
<article-title xml:lang="en"><![CDATA[Diabetic Macroangiopathy and Stem Cell Autotransplantation]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Moreira Martínez]]></surname>
<given-names><![CDATA[Marta Marisel]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Conchado Martínez]]></surname>
<given-names><![CDATA[Julio Héctor]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Hernández Rojas]]></surname>
<given-names><![CDATA[Ana Lidia]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Hernández Díaz]]></surname>
<given-names><![CDATA[Aida Rosa]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Ramos Miranda]]></surname>
<given-names><![CDATA[Rosmery]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Hernández Moreira]]></surname>
<given-names><![CDATA[Marta Yaimara]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Universidad de Ciencias Médicas de Pinar del Río Hospital General Docente &#8220;Abel Santamaría Cuadrado&#8221;.  ]]></institution>
<addr-line><![CDATA[Pinar del Rio ]]></addr-line>
<country>Cuba</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>02</month>
<year>2022</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>02</month>
<year>2022</year>
</pub-date>
<volume>26</volume>
<numero>1</numero>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://scielo.sld.cu/scielo.php?script=sci_arttext&amp;pid=S1561-31942022000100009&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.sld.cu/scielo.php?script=sci_abstract&amp;pid=S1561-31942022000100009&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.sld.cu/scielo.php?script=sci_pdf&amp;pid=S1561-31942022000100009&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[RESUMEN  Introducción: es evidente el potencial terapéutico de las células madre en el tratamiento de arteriopatías periféricas.  Objetivo:  evaluar la seguridad y eficacia del procedimiento en la Macroangiopatía Diabética.  Métodos:  estudio observacional, prospectivo y longitudinal, que incluyó a 50 pacientes. Se monitorearon durante 12 meses con el índice de presiones, la distancia de claudicación y la evaluación del dolor. El análisis se fundamentó en la determinación de los valores medios, los por cientos y la aplicación de los test de proporciones y de Duncan.  Resultados:  predominaron los pacientes masculinos y el grupo de 60-70 años. En el primer mes de tratamiento mejoró el dolor y la distancia de claudicación de manera significativa. En ningún caso se observó efectos adversos secundarios al tratamiento  Conclusiones:  resultó un procedimiento eficaz y sin complicaciones, lo que estimula a la continuación de los estudios clínicos en este campo.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[ABSTRACT  Introduction:  the therapeutic potential of stem cells in the treatment of peripheral arteriopathy is evident.  Objective:  to assess the safety and efficacy of the procedure in diabetic macroangiopathy.  Methods:  an observational, prospective and longitudinal study, which included 50 patients. They were monitored for 12 months with blood pressure index, claudication distance and pain assessment. The analysis was based on the determination of mean values, percentile values and the application of proportions and Duncan's test.  Results:  male patients and the age group from 60-70 years old predominated. In the first month of treatment, pain and claudication distance improved significantly. No adverse side effects were observed in any case.  Conclusions:  the procedure was effective and without complications, which encourages the continuation of clinical studies in this field.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[CÉLULAS MADRE]]></kwd>
<kwd lng="es"><![CDATA[CLAUDICACIÓN INTERMITENTE]]></kwd>
<kwd lng="es"><![CDATA[CMN-SP AUTÓLOGAS]]></kwd>
<kwd lng="es"><![CDATA[INDICÉ TOBILLO-BRAZO]]></kwd>
<kwd lng="en"><![CDATA[STEM CELLS]]></kwd>
<kwd lng="en"><![CDATA[INTERMITTENT CLAUDICATION]]></kwd>
<kwd lng="en"><![CDATA[AUTOLOGOUS CMN-SP, ANKLE-ARM INDEX.]]></kwd>
</kwd-group>
</article-meta>
</front><back>
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