<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>1561-3194</journal-id>
<journal-title><![CDATA[Revista de Ciencias Médicas de Pinar del Río]]></journal-title>
<abbrev-journal-title><![CDATA[Rev Ciencias Médicas]]></abbrev-journal-title>
<issn>1561-3194</issn>
<publisher>
<publisher-name><![CDATA[Editorial Ciencias Médicas]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S1561-31942022000600019</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Nefritis túbulo intersticial aguda por cefalexina, a propósito de un caso]]></article-title>
<article-title xml:lang="en"><![CDATA[Acute tubulointerstitial nephritis due to cephalexin. Apropos of a case]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Pineda-Daniel]]></surname>
<given-names><![CDATA[Oderkys]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Fortún-Prieto]]></surname>
<given-names><![CDATA[Adalberto]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Carballo-Gutierrez]]></surname>
<given-names><![CDATA[Javier Luis]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Hernández-Luis]]></surname>
<given-names><![CDATA[José Jairan]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Universidad de Ciencias Médicas de Pinar del Río Hospital Augusto César Sandino ]]></institution>
<addr-line><![CDATA[Pinar del Río ]]></addr-line>
<country>Cuba</country>
</aff>
<aff id="Af2">
<institution><![CDATA[,Universidad de Ciencias Médicas de Pinar del Río. Hospital Clínico Quirúrgico Docente León Cuervo Rubio ]]></institution>
<addr-line><![CDATA[Pinar del Río ]]></addr-line>
<country>Cuba</country>
</aff>
<aff id="Af3">
<institution><![CDATA[,Universidad de Ciencias Médicas de Pinar del Río Hospital General Docente Abel Santamaría Cuadrado ]]></institution>
<addr-line><![CDATA[Pinar del Río. ]]></addr-line>
<country>Cuba</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>12</month>
<year>2022</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>12</month>
<year>2022</year>
</pub-date>
<volume>26</volume>
<numero>6</numero>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://scielo.sld.cu/scielo.php?script=sci_arttext&amp;pid=S1561-31942022000600019&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.sld.cu/scielo.php?script=sci_abstract&amp;pid=S1561-31942022000600019&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.sld.cu/scielo.php?script=sci_pdf&amp;pid=S1561-31942022000600019&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[RESUMEN  Introducción:  la nefritis túbulo intersticial aguda se refiere a un tipo de daño renal que afecta principalmente el intersticio y ocasiona lesión aguda potencialmente reversible. Su curso puede ser subclínico o con deterioro progresivo, hasta evolucionar hacia la enfermedad renal crónica. Su manejo incluye la suspensión del fármaco responsable y la utilización de esteroides cuando la condición es de origen medicamentoso o autoinmune. Si se identifica de forma oportuna y se trata adecuadamente, su pronóstico generalmente es favorable.  Presentación de caso:  se reporta una paciente joven con historia de buena salud, que después de un proceder estomatológico recibió tratamiento con cefalexina oral durante siete días y desarrolló nefritis túbulo intersticial aguda comprobada clínica e histológicamente que respondió satisfactoriamente al tratamiento habitual de la enfermedad, lo que indica la necesidad de tener en cuenta su posibilidad, aún en situaciones clínicas habituales, e incrementar los conocimientos de los profesionales médicos sobre este trastorno que puede, incluso, ser causa de enfermedad renal crónica así como evitar el uso de antibióticos cuando no son una estricta necesidad.  Conclusiones:  la nefritis túbulo intersticial aguda es una complicación que puede estar presente después del uso de cefalosporinas, incluidas las de primera generación administrada por vía oral, en el tratamiento de enfermedades comunes con un pronóstico favorable.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[ ABSTRACT  Introduction:  acute tubulointerstitial nephritis refers to a type of renal damage that mainly affects the interstitium and causes potentially reversible acute injury. Its course may be subclinical or with progressive deterioration, until it evolves into chronic renal disease. Its management includes the suspension of the responsible drug and the use of steroids when the condition is of drug or autoimmune origin. If identified in a timely manner and adequately treated, its prognosis is generally favorable.  Case presentation:  we report a young patient with a history of good health, who after a stomatological procedure received treatment with oral cephalexin for seven days and developed acute tubulointerstitial nephritis clinically and histologically proven that responded satisfactorily to the usual treatment of the disease, which indicates the need to take into account its possibility, even in usual clinical situations, and increase the knowledge of medical professionals about this disorder that can even be a cause of chronic kidney disease and avoid the use of antibiotics when they are not a strict necessity.  Conclusions:  acute tubulointerstitial nephritis is a complication that may be present after the use of cephalosporins, including those of the first generation administered orally, in the treatment of common diseases with a favorable prognosis.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[LESIÓN RENAL AGUDA]]></kwd>
<kwd lng="es"><![CDATA[NEFRITIS TÚBULO INTERSTICIAL]]></kwd>
<kwd lng="es"><![CDATA[CEFALEXINA]]></kwd>
<kwd lng="es"><![CDATA[BIOPSIA]]></kwd>
<kwd lng="en"><![CDATA[ACUTE KIDNEY INJURY]]></kwd>
<kwd lng="en"><![CDATA[NEPHRITIS, INTERSTITIAL]]></kwd>
<kwd lng="en"><![CDATA[CEPHALEXIN]]></kwd>
<kwd lng="en"><![CDATA[BIOPSY]]></kwd>
</kwd-group>
</article-meta>
</front><back>
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