<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>1682-0037</journal-id>
<journal-title><![CDATA[Revista Cubana de Angiología y Cirugía Vascular]]></journal-title>
<abbrev-journal-title><![CDATA[Rev Cubana Angiol Cir Vasc]]></abbrev-journal-title>
<issn>1682-0037</issn>
<publisher>
<publisher-name><![CDATA[Centro Nacional de Información de Ciencias MédicasEditorial Ciencias Médicas]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S1682-00372020000200009</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Recidiva de úlcera del pie en pacientes diabéticos tratados con Heberprot-P®]]></article-title>
<article-title xml:lang="en"><![CDATA[Foot ulcer recurrence in diabetic patients who received heberprot-p® treatment]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Castañeira Jorge]]></surname>
<given-names><![CDATA[Elaine]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Febles Sanabria]]></surname>
<given-names><![CDATA[Ridel Jesús]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Hospital Universitario Clínico-Quirúrgico Comandante &#8220;Faustino Pérez Hernández&#8221;  ]]></institution>
<addr-line><![CDATA[Matanzas ]]></addr-line>
<country>Cuba</country>
</aff>
<aff id="Af2">
<institution><![CDATA[,Universidad de Ciencias Médicas de Matanzas  ]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
<country>Cuba</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>08</month>
<year>2020</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>08</month>
<year>2020</year>
</pub-date>
<volume>21</volume>
<numero>2</numero>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://scielo.sld.cu/scielo.php?script=sci_arttext&amp;pid=S1682-00372020000200009&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.sld.cu/scielo.php?script=sci_abstract&amp;pid=S1682-00372020000200009&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.sld.cu/scielo.php?script=sci_pdf&amp;pid=S1682-00372020000200009&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[RESUMEN  Introducción:  El Heberprot-P® es un medicamento novedoso y único en su tipo, prescrito para la terapia de la úlcera del pie diabético.  Objetivo:  Evaluar la frecuencia y las características de la recidiva de úlcera del pie en pacientes diabéticos tratados con Heberprot-P®.  Métodos: Se realizó una investigación descriptiva-retrospectiva. La población estuvo constituida por 16 pacientes con recidiva de úlcera de pie diabético de los 841 tratados con Heberprot-P® en policlínicos y hospitales de la provincia de Matanzas desde enero hasta diciembre de 2018. Las variables revisadas fueron llevadas a una base de datos, y los resultados obtenidos se tabularon y se expresaron en frecuencias absolutas y relativas. Se respetaron las consideraciones éticas requeridas para este estudio.  Resultados: El grupo de edades 61-75 años y los diabéticos de tipo 2 fueron los más afectados, y no existieron diferencias entre ambos sexos. El pie diabético neuropático con una severidad Wagner 2 se manifestó con mayor frecuencia. Asimismo, a partir de la primera lesión y la recidiva se observó un gran número de pacientes con la enfermedad entre las 13 y 16 semanas, y al 56,2 % de estos se les administró, durante la primera lesión, de 6 a 12 dosis de Heberprot-P®. El cierre total de la lesión en el desenlace fue lo más encontrado en la población de estudio, y el 1,9 % de los pacientes tratados presentó una recidiva de esta.  Conclusiones:  Quedaron expuestas la frecuencia y las características de la recidiva de la úlcera del pie en los pacientes diabéticos tratados con Heberprot-P®.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[ABSTRACT  Introduction:  Heberprot-P® is a novel medicine, unique among its kind, prescribed for diabetic foot ulcer therapy.  Objective:  To evaluate frequency and characteristics of foot ulcer recurrence among diabetic patients treated with Heberprot-P®.  Methods:  A descriptive-retrospective research was carried out. The study population consisted of 16 patients with diabetic foot ulcer recurrence from among the 841 treated with Heberprot-P® in polyclinics and hospitals in Matanzas Province from January to December 2018. The variables reviewed were taken to a database, and the results obtained were represented in charts and expressed in absolute and relative frequencies. The ethical considerations required for this study were respected.  Results:  The age group 61-75 years and type 2 diabetic patients were the most affected. There were no differences between both sexes. Neuropathic diabetic foot with Wagner 2 severity appeared more frequently. Likewise, after the first injury and recurrence, a large number of patients with the disease were observed at 13-16 weeks, 56.2% of whom, were administered, during the first injury, 6-12 doses of Heberprot-P®. The total closure of the lesion was the most found outcome in the study population, and 1.9% of the treated patients presented recurrence of this.  Conclusions:  The frequency and characteristics of foot ulcer recurrence in diabetic patients treated with Heberprot-P® were exposed.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[diabetes mellitus]]></kwd>
<kwd lng="es"><![CDATA[úlcera del pie diabético]]></kwd>
<kwd lng="es"><![CDATA[recidiva]]></kwd>
<kwd lng="en"><![CDATA[diabetes mellitus]]></kwd>
<kwd lng="en"><![CDATA[diabetic foot ulcer]]></kwd>
<kwd lng="en"><![CDATA[recurrence]]></kwd>
</kwd-group>
</article-meta>
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</article>
