<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>1727-897X</journal-id>
<journal-title><![CDATA[MediSur]]></journal-title>
<abbrev-journal-title><![CDATA[Medisur]]></abbrev-journal-title>
<issn>1727-897X</issn>
<publisher>
<publisher-name><![CDATA[Universidad de Ciencias Médicas de Cienfuegos, Centro Provincial de Ciencias Médicas, Provincia de Cienfuegos.]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S1727-897X2019000500633</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Diabetes y malformaciones congénitas. Cienfuegos, 2005-2015]]></article-title>
<article-title xml:lang="en"><![CDATA[Diabetes and congenital malformations. Cienfuegos, 2005-2015]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Padrón Aguilera]]></surname>
<given-names><![CDATA[Oramis Isabel]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Santos Solí]]></surname>
<given-names><![CDATA[Maylé]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Vázquez Martínez]]></surname>
<given-names><![CDATA[Vivian Rosa]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Torres González]]></surname>
<given-names><![CDATA[Cristóbal Jorge]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Barberis Pérez]]></surname>
<given-names><![CDATA[Gladys Bárbara]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Universidad de Ciencias Médicas de Cienfuegos Facultad de Ciencias Médicas ]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
<country>Cuba</country>
</aff>
<aff id="Af2">
<institution><![CDATA[,Hospital General Universitario Gustavo Aldereguía Lima  ]]></institution>
<addr-line><![CDATA[Cienfuegos Cienfuegos]]></addr-line>
<country>Cuba</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>10</month>
<year>2019</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>10</month>
<year>2019</year>
</pub-date>
<volume>17</volume>
<numero>5</numero>
<fpage>633</fpage>
<lpage>640</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://scielo.sld.cu/scielo.php?script=sci_arttext&amp;pid=S1727-897X2019000500633&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.sld.cu/scielo.php?script=sci_abstract&amp;pid=S1727-897X2019000500633&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.sld.cu/scielo.php?script=sci_pdf&amp;pid=S1727-897X2019000500633&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[RESUMEN  Fundamento:  la diabetes constituye el trastorno metabólico que más repercusión tiene sobre la salud materna y su descendencia, con mayor énfasis en las malformaciones congénitas.  Objetivo:  describir las malformaciones congénitas en hijos de madres diabéticas en la provincia de Cienfuegos.  Métodos:  estudio de serie de casos realizado en Cienfuegos, desde enero de 2005 a diciembre de 2015, sobre fetos y neonatos con malformaciones congénitas hijos de madres diabéticas. Los datos se obtuvieron del modelo del Registro Cubano de Malformaciones Congénitas y Prenatales y otros documentos del departamento de archivos del Hospital Materno de Cienfuegos y del Centro Provincial de Genética Médica. Se analizaron variables sociodemográficas, maternas, tipo de malformación y el diagnóstico pre y posnatal según el caso.  Resultados:  la incidencia de malformaciones en hijos de madres diabéticas fue del 3,4 %; predominaron las malformaciones mayores, dentro de ellas, las cardiovasculares. No existieron diferencias en la aparición de malformaciones entre la diabetes mellitus pregestacional y la gestacional. Los factores de riesgo más frecuentes fueron: el sobrepeso materno, las enfermedades no transmisibles y el uso de medicamentos en el embarazo.  Conclusiones:  en los hijos de madres diabéticas predominaron las malformaciones congénitas cardiovasculares y se relacionaron con el sobrepeso y la comorbilidad materna.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[ABSTRACT  Foundation:  diabetes is the metabolic disorder with the greatest impact on maternal health and its offspring, with greater emphasis on congenital malformations.  Objective:  to describe congenital malformations in children of diabetic mothers in the province of Cienfuegos.  Methods:  case series study conducted in Cienfuegos, from January 2005 to December 2015, on fetuses and neonates with congenital malformations, children of diabetic mothers. The data were obtained from the model of the Cuban Registry of Congenital and Prenatal Malformations and other documents of the archives department of the Maternity Hospital of Cienfuegos and the Provincial Center of Medical Genetics. We analyzed socio- demographic, maternal variables, type of malformation and pre and postnatal diagnosis according to the case.  Results:  the incidence of malformations in children of diabetic mothers was 3.4%; Major malformations predominated, including cardiovascular malformations. There were no differences in the appearance of malformations between pre-gestational and gestational diabetes mellitus. The most frequent risk factors were: maternal overweight, non-communicable diseases and the use of drugs in pregnancy.  Conclusions:  congenital cardiovascular malformations predominated in children of diabetic mothers and were related to overweight and maternal comorbidity.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[diabetes mellitus]]></kwd>
<kwd lng="es"><![CDATA[embarazo]]></kwd>
<kwd lng="es"><![CDATA[anomalías congénitas]]></kwd>
<kwd lng="en"><![CDATA[diabetes mellitus]]></kwd>
<kwd lng="en"><![CDATA[pregnancy]]></kwd>
<kwd lng="en"><![CDATA[congenital abnormalities]]></kwd>
</kwd-group>
</article-meta>
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<surname><![CDATA[Gómez Baute]]></surname>
<given-names><![CDATA[R]]></given-names>
</name>
<name>
<surname><![CDATA[González Iglesias]]></surname>
<given-names><![CDATA[Y.]]></given-names>
</name>
</person-group>
<article-title xml:lang=""><![CDATA[Evaluación de la eficacia diagnóstica por ultrasonografía en malformaciones congénitas mayores]]></article-title>
<source><![CDATA[Rev Cubana Obstet Ginecol]]></source>
<year>2002</year>
<volume>128</volume>
<numero>3</numero>
<issue>3</issue>
<page-range>14</page-range></nlm-citation>
</ref>
</ref-list>
</back>
</article>
