<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>1727-897X</journal-id>
<journal-title><![CDATA[MediSur]]></journal-title>
<abbrev-journal-title><![CDATA[Medisur]]></abbrev-journal-title>
<issn>1727-897X</issn>
<publisher>
<publisher-name><![CDATA[Universidad de Ciencias Médicas de Cienfuegos, Centro Provincial de Ciencias Médicas, Provincia de Cienfuegos.]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S1727-897X2021000601021</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Esplenomegalia gigante por enfermedad de Gaucher]]></article-title>
<article-title xml:lang="en"><![CDATA[Giant splenomegaly due to Gaucher disease]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Sardiñas Ponce]]></surname>
<given-names><![CDATA[Raysy]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Guerra Leal]]></surname>
<given-names><![CDATA[Obel Alcides]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Verdecia]]></surname>
<given-names><![CDATA[Servando Roig]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Hospital General Docente Dr. Enrique Cabrera Cossío  ]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>12</month>
<year>2021</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>12</month>
<year>2021</year>
</pub-date>
<volume>19</volume>
<numero>6</numero>
<fpage>1021</fpage>
<lpage>1027</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://scielo.sld.cu/scielo.php?script=sci_arttext&amp;pid=S1727-897X2021000601021&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.sld.cu/scielo.php?script=sci_abstract&amp;pid=S1727-897X2021000601021&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.sld.cu/scielo.php?script=sci_pdf&amp;pid=S1727-897X2021000601021&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[RESUMEN La enfermedad de Gaucher es la enfermedad más frecuente del grupo de las enfermedades de depósito lisosomal, la cual pertenece a los errores innatos del metabolismo. Se produce acumulación de glucocerebrósidos en diferentes órganos y como consecuencia, el desarrollo de síntomas y signos multisistémicos que se establecen de manera crónica y progresiva, tales como: visceromegalias, destrucción ósea y citopenias periféricas. Se presenta un paciente masculino de 43 años con diagnóstico de esta enfermedad desde la infancia, que desarrolló esplenomegalia gigante con hiperesplenismo, por lo que requirió esplenectomía, obteniéndose buenos resultados con el tratamiento quirúrgico.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[ABSTRACT Gaucher disease is the most common disease of the lysosomal storage diseases group comprised within innate errors of metabolism. There is glucocerebrosides accumulation in different organs and as a consequence, the development of symptoms and multisystemic signs that are established in a chronic and progressive way, such as: visceromegaly, bone destruction and peripheral cytopenias. A 43-years-old male patient is presented with a diagnosis of this disease since childhood, who developed giant splenomegaly with hypersplenism, for which he required splenectomy, obtaining good results with surgical treatment.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[enfermedad de Gaucher]]></kwd>
<kwd lng="es"><![CDATA[esplenomegalia]]></kwd>
<kwd lng="es"><![CDATA[esplenectomía]]></kwd>
<kwd lng="en"><![CDATA[Gaucher´s disease]]></kwd>
<kwd lng="en"><![CDATA[splenomegaly]]></kwd>
<kwd lng="en"><![CDATA[splenectomy]]></kwd>
</kwd-group>
</article-meta>
</front><back>
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</article>
