<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>1727-897X</journal-id>
<journal-title><![CDATA[MediSur]]></journal-title>
<abbrev-journal-title><![CDATA[Medisur]]></abbrev-journal-title>
<issn>1727-897X</issn>
<publisher>
<publisher-name><![CDATA[Universidad de Ciencias Médicas de Cienfuegos, Centro Provincial de Ciencias Médicas, Provincia de Cienfuegos.]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S1727-897X2022000100146</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Trombocitopenia inducida por heparina de bajo peso molecular en un paciente con COVID-19]]></article-title>
<article-title xml:lang="en"><![CDATA[Low molecular weight heparin-induced thrombocytopenia in a patient with COVID-19]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Ortiz Legrá]]></surname>
<given-names><![CDATA[Ruber]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Pérez Castillo]]></surname>
<given-names><![CDATA[Mayvi]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Peña Batista]]></surname>
<given-names><![CDATA[Andrés Pavel]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Hospital General Universitario Dr. Gustavo Aldereguía Lima  ]]></institution>
<addr-line><![CDATA[Cienfuegos ]]></addr-line>
<country>Cuba</country>
</aff>
<aff id="Af2">
<institution><![CDATA[,Universidad de Ciencias Médicas de Cienfuegos  ]]></institution>
<addr-line><![CDATA[Cienfuegos ]]></addr-line>
<country>Cuba</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>02</month>
<year>2022</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>02</month>
<year>2022</year>
</pub-date>
<volume>20</volume>
<numero>1</numero>
<fpage>146</fpage>
<lpage>153</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://scielo.sld.cu/scielo.php?script=sci_arttext&amp;pid=S1727-897X2022000100146&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.sld.cu/scielo.php?script=sci_abstract&amp;pid=S1727-897X2022000100146&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.sld.cu/scielo.php?script=sci_pdf&amp;pid=S1727-897X2022000100146&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[RESUMEN Aunque el sistema respiratorio resulta el más afectado por la COVID-19, hoy conocemos que también predispone a la enfermedad tromboembólica, debido a la excesiva inflamación, activación plaquetaria, disfunción endotelial y estasis que suele ocasionar. La aplicación profiláctica de heparinas de bajo peso molecular ha sido una de las principales recomendaciones en pacientes hospitalizados por esta emergencia sanitaria, práctica no exenta de eventos secundarios, y que tiene entre sus complicaciones más graves la trombocitopenia. Con el propósito de alertar sobre la aparición de esta entidad y evitar mayores complicaciones, se expone un caso en el cual se constató trombocitopenia luego de recibir siete dosis de enoxaparina, y que luego de 48 horas de suspenderse esta, comenzó el ascenso progresivo del número de plaquetas, hasta alcanzar sus niveles de normalidad.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[ABSTRACT Although the respiratory system is the most affected by COVID-19, today we know that it also predisposes to thromboembolic disease, due to the excessive inflammation, platelet activation, endothelial dysfunction and stasis that it usually causes. The prophylactic application of low molecular weight heparins has been one of the main recommendations in patients hospitalized for this health emergency, a practice that is not exempt from secondary events, and which has thrombocytopenia among its most serious complications. In order to alert about the appearance of this entity and avoid further complications, a case is presented in which thrombocytopenia was found after receiving seven doses of enoxaparin, and after 48 hours of suspending this, the progressive rise of platelets in number began, until they reach their normal levels.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[Infecciones por coronavirus]]></kwd>
<kwd lng="es"><![CDATA[trombocitopenia]]></kwd>
<kwd lng="es"><![CDATA[heparina de bajo-peso-molecular]]></kwd>
<kwd lng="en"><![CDATA[Coronavirus infections]]></kwd>
<kwd lng="en"><![CDATA[thrombocytopenia]]></kwd>
<kwd lng="en"><![CDATA[heparin, low-molecular-weight]]></kwd>
</kwd-group>
</article-meta>
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